Jehan A. Mohammad
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View article: Association between intelectin-1, sleep quality, and insulin resistance in infertile women of reproductive age
Association between intelectin-1, sleep quality, and insulin resistance in infertile women of reproductive age Open
Intelectin-1, in addition to its anti-inflammatory activity, may play a role in the pathogenesis of type II diabetes and sleep disorders. However, its exact role in humans still requires further investigation. This study was conducted on 1…
View article: Leptin: Biological Functions and Metabolic Regulation in Type 2 Diabetes Mellitus
Leptin: Biological Functions and Metabolic Regulation in Type 2 Diabetes Mellitus Open
View article: IRISIN, OBESITY AND TYPE II DIABETES MELLITUS
IRISIN, OBESITY AND TYPE II DIABETES MELLITUS Open
Background: Irisin is an exercise-induced cytokine that is expressed as a biologically active peptide in many organs and tissues. Physical exercise and coldness are the main triggers for irisin release. Many studies have found that the lev…
View article: Comparative evaluation of serum apelin, visfatin, and lipid levels in overweight hypertensive patients on enalapril versus telmisartan therapy
Comparative evaluation of serum apelin, visfatin, and lipid levels in overweight hypertensive patients on enalapril versus telmisartan therapy Open
Objectives. Visfatin and apelin are two adipokines that recently gained a special interest in hypertension research as they may have a role in the pathogenesis of hypertension and are closely related to the renin-angiotensin system. This s…
View article: Comparative Effects of Candesartan Versus Enalapril on Apelin, Visfatin, and Lipid Levels in Non-obese Hypertensive Patients
Comparative Effects of Candesartan Versus Enalapril on Apelin, Visfatin, and Lipid Levels in Non-obese Hypertensive Patients Open
Lower apelin and higher visfatin levels are associated with newly diagnosed patients with hypertension. Interestingly, the findings suggest that ACE inhibition and angiotensin receptor blockade by enalapril and candesartan, respectively, p…
View article: RESISTIN IN RHEUMATOID ARTHRITIS
RESISTIN IN RHEUMATOID ARTHRITIS Open
Rheumatoid arthritis (RA) is a chronic multisystem illness that affects millions of individuals.The primary goal of RA therapy is to improve patients' quality of life by reducing pain severity, preserving or improving functional capability…
View article: Effects of Angiotensin Receptor Blockers on Apelin and Visfatin in Hypertension
Effects of Angiotensin Receptor Blockers on Apelin and Visfatin in Hypertension Open
Angiotensin receptor blockers (ARBs) are crucial in the management of cardiovascular diseases, by targeting the renin-angiotensin system, which plays a vital role in cardiovascular health. These drugs control hypertension and fluid imbalan…
View article: THE ROLE OF VASPIN IN RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS
THE ROLE OF VASPIN IN RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS Open
Background: Adipo(cyto)kines are substances derived from adipose tissue that influence central processes in the body like inflammation, in addition to their effect on metabolism. Adipocytokines are implicated in inflammatory pathways that …
View article: Levels of adiponectin, malondialdehyde and lipid profile in women with polycystic ovary syndrome
Levels of adiponectin, malondialdehyde and lipid profile in women with polycystic ovary syndrome Open
View article: Adipsin and Leptin Levels in Type 2 Diabetic Patients on Sitagliptin and Metformin Versus Metformin Therapy
Adipsin and Leptin Levels in Type 2 Diabetic Patients on Sitagliptin and Metformin Versus Metformin Therapy Open
Adipsin is low and leptin is high in diabetic patients which support its possible use as a biomarker for type 2 diabetes. Accordingly, the modification of these adipokines, via the use of drug therapy, has advantageous effects on the cardi…
View article: Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management
Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management Open
Background: Angiotensin-converting enzyme (ACE) Inhibitors are medications pivotal in cardiovascular disease management, impacting the renin-angiotensin system which plays a critical role in cardiovascular health. These inhibitors not only…
View article: Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management
Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management Open
View article: ASSESSMENT OF OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN TYPE 1 DIABETES MELLITUS
ASSESSMENT OF OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN TYPE 1 DIABETES MELLITUS Open
Increased oxidative stress appears to be a risk factor for insulin resistance, dyslipidemia, β-cell dysfunction, impaired glucose tolerance, and, eventually, diabetes mellitus.The majority of research shows that oxidative stress plays a ro…
View article: HYPERLIPIDEMIA CONNOTED VITIATION OF SERUM ADIPOKINES AND REDOX IMBALANCES
HYPERLIPIDEMIA CONNOTED VITIATION OF SERUM ADIPOKINES AND REDOX IMBALANCES Open
Background and objectives: Atherosclerosis is the underlying pathology of ischemic heart disease.There are many aggravating metabolic and oxidant parameters which are participating together overwhelming the pathology of vascular stenosis.A…
View article: THERAPEUTIC USE OF METFORMIN IN THYROID CANCER
THERAPEUTIC USE OF METFORMIN IN THYROID CANCER Open
Thyroid cancer is a rare type of malignancy.However, thyroid cancer constitutes more than 90 % of endocrine tumors.Metformin (N', N'-dimethybiguanide) is the most commonly prescribed drug in the world, and the annual number of prescription…
View article: Hepcidin as a Potential Biomarker for the Diagnosis of Anemia
Hepcidin as a Potential Biomarker for the Diagnosis of Anemia Open
There are several blood-based markers to assess iron stores, but they all have some limitations. Hepcidin, a low-molecular-weight peptide hormone, is produced mainly by the liver. It is the main regulator of iron homeostasis by preventing …
View article: Figure 1 from: Mohammad JA, Almulathanon AAY, Fathi FH (2021) Assessment of the effects of metformin and glibenclamide on the concentration of selected trace elements in type 2 diabetic patients. Pharmacia 68(4): 845-849. https://doi.org/10.3897/pharmacia.68.e72080
Figure 1 from: Mohammad JA, Almulathanon AAY, Fathi FH (2021) Assessment of the effects of metformin and glibenclamide on the concentration of selected trace elements in type 2 diabetic patients. Pharmacia 68(4): 845-849. https://doi.org/10.3897/pharmacia.68.e72080 Open
Figure 1 Effects of metformin versus glibenclamide on serum concentrations of A) Cu, B) Zn, and C) Mg in type 2 diabetic patients.* indicates statistically significant differences compared to the control group (**p < 0.01; ***p < 0.001; **…
View article: Assessment of the effects of metformin and glibenclamide on the concentration of selected trace elements in type 2 diabetic patients
Assessment of the effects of metformin and glibenclamide on the concentration of selected trace elements in type 2 diabetic patients Open
Metformin and glibenclamide may have beneficial effects on the levels of trace elements in diabetic patients. The aim of the current study was to assess the effects of metformin and glibenclamide on the concentrations of copper (Cu), zinc …
View article: Hepcidin as a Potential Biomarker for Diagnosis of Anaemia
Hepcidin as a Potential Biomarker for Diagnosis of Anaemia Open
There are several blood-based markers to assess iron stores, but they all have some limitations.Hepcidin, a low-molecular-weight peptide hormone, is mainly produced by liver.It is the main regulator of iron homeostasis through prevention i…
View article: Comparative evaluation of cystatin C and neutrophil gelatinase-associated lipocalin in patients with thalassemia major versus thalassemia intermedia
Comparative evaluation of cystatin C and neutrophil gelatinase-associated lipocalin in patients with thalassemia major versus thalassemia intermedia Open
Kidney disorders are long-term complications in thalassemia patients, especially with the high life expectancy of these patients. Proper evaluation of kidney impairment in β-thalassemia patients can be difficult due to higher intake of iro…
View article: Evaluation the effects of insulin on oxidant/antioxidant status in type 1 diabetic patients
Evaluation the effects of insulin on oxidant/antioxidant status in type 1 diabetic patients Open
Earlier works have revealed increased generation of reactive oxygen species (ROS) and decreased antioxidant levels in type 1 diabetes mellitus (T1DM). The current study aimed to investigate the effect of mixed insulin therapy on oxidative …
View article: Silent hyperlipidaemia modulated vascular endothelial markers
Silent hyperlipidaemia modulated vascular endothelial markers Open
The aetiology of ischemic heart diseases is mainly based on atherosclerosis of coronary artery. Inflammation and oxidative reactions are initiating and aggravating the illness resulting in pathological remodelling of vasculaturze at site o…
View article: Comparative effects of metformin and glibenclamide on the redox balance in type 2 diabetic patients
Comparative effects of metformin and glibenclamide on the redox balance in type 2 diabetic patients Open
It is known that there is a strong association between oxidative stress and insulin resistance in type 2 diabetes mellitus (T2DM). Although the role of glibenclamide in diabetes treatment has been evaluated, there is only limited evidence …
View article: Assessment the effects of insulin on adiponectin, nitric oxide, myeloperoxidase and lipid profile in type 1 diabetic patients
Assessment the effects of insulin on adiponectin, nitric oxide, myeloperoxidase and lipid profile in type 1 diabetic patients Open
Type 1 diabetes (T1DM) is well recognized risk factor cardiovascular disease (CVD). Insulin therapy is recommended for all patients with type 1 diabetes. Previous findings showed that diabetes impairs endothelial function and increased glu…