Jenée Mitchell
YOU?
Author Swipe
View article: Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions
Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions Open
Langerhans cell histiocytosis (LCH) lesions contain an inflammatory infiltrate of immune cells including myeloid-derived LCH cells. Cell-signaling proteins within the lesion environment suggest that LCH cells and T cells contribute majorly…
View article: Does CD1a Expression Influence T Cell Function in Patients With Langerhans Cell Histiocytosis?
Does CD1a Expression Influence T Cell Function in Patients With Langerhans Cell Histiocytosis? Open
Langerhans cell histiocytosis lesions are characterized by CD1a+ myeloid lineage LCH cells and an inflammatory infiltrate of cytokines and immune cells, including T cells. T cells that recognize CD1a may be implicated in the pathology of m…
View article: Langerhans cell histiocytosis: A malignant myeloid neoplasm or disorder of immune regulation?
Langerhans cell histiocytosis: A malignant myeloid neoplasm or disorder of immune regulation? Open
Langerhans cell histiocytosis (LCH) is characterised by lesions containing LCH cells, which are myeloid-derived dendritic cells that co-express CD1a and CD207 (langerin). In addition to LCH cells, these lesions also contain an inflammatory…
View article: Patients with both Langerhans cell histiocytosis and Crohn’s disease highlight a common role of interleukin‐23
Patients with both Langerhans cell histiocytosis and Crohn’s disease highlight a common role of interleukin‐23 Open
Aim To present the first case series of patients with Langerhans cell histiocytosis (LCH) also affected by Crohn's disease (CD), both of which are granulomatous diseases, and in LCH investigate the role of interleukin (IL)‐23, which is a w…
View article: Abnormalities in T cell lineages from patients with Langerhans cell histiocytosis
Abnormalities in T cell lineages from patients with Langerhans cell histiocytosis Open
Langerhans cell histiocytosis (LCH) is a rare inflammatory disease characterised by lesions containing CD1a+ myeloid lineage ‘LCH’ cells. Other immune cells such as T cells are also present within LCH lesions and the cytokine milieu sugges…