Jenna Ariel Lieberman
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View article: Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants
Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants Open
View article: Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing Open
View article: Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants
Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants Open
Since the start of the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 2 million deaths worldwide. Multiple vaccines have been deployed to date, but the contin…
View article: Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core
Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core Open
View article: mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants Open
View article: mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants Open
To date severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 100 million individuals resulting in over two million deaths. Many vaccines are being deployed to prevent coronavirus disease 2019 (COVID-19) including …
View article: Control of RNA Polymerase II Promoter-Proximal Pausing by DNA Supercoiling
Control of RNA Polymerase II Promoter-Proximal Pausing by DNA Supercoiling Open
View article: Structure of the Mammalian Mediator
Structure of the Mammalian Mediator Open
The Mediator complex plays an essential and multi-faceted role in regulation of RNA polymerase II transcription in all eukaryotes. Structural analysis of yeast Mediator has provided an understanding of the conserved core of the complex and…
View article: ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links
ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links Open
Resolving a DNA-protein cross-link Topoisomerase 2 (TOP2) creates DNA double-strand breaks to regulate DNA topology and is critical for processes such as replication and transcription. A covalent complex between TOP2 and DNA (TOP2cc) is an…
View article: Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme Open
View article: MB-18DYSFUNCTION OF THE CHROMATIN REMODELER Chd7 CAUSES ABNORMAL CEREBELLAR DEVELOPMENT AND ACCELERATES MEDULLOBLASTOMA FORMATION
MB-18DYSFUNCTION OF THE CHROMATIN REMODELER Chd7 CAUSES ABNORMAL CEREBELLAR DEVELOPMENT AND ACCELERATES MEDULLOBLASTOMA FORMATION Open