Jianying Wang
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View article: Dissecting causal relationships between immune cells, blood metabolites, and diabetic nephropathy
Dissecting causal relationships between immune cells, blood metabolites, and diabetic nephropathy Open
This MR study provides novel genetic evidence of a significant relationship between certain immune cells and DN, with blood metabolites playing a mediating role. These findings offer valuable insights for potential clinical interventions.
View article: Examining the Correlational Interaction of Environmental Fluoride and Selenium and Its Impact on Dental Fluorosis in Coal-Burning Regions of Southwest China
Examining the Correlational Interaction of Environmental Fluoride and Selenium and Its Impact on Dental Fluorosis in Coal-Burning Regions of Southwest China Open
Epidemiological and geochemical evidence suggests that coal-burning fluorosis in Southwest China is mechanistically linked to the presence of fluoride-rich geochemical anomalies. However, the severity of dental fluorosis does not consisten…
View article: CrossGraphNet: a cross-spatiotemporal graph-based method for traffic speed reconstruction using remote sensing vehicle detection
CrossGraphNet: a cross-spatiotemporal graph-based method for traffic speed reconstruction using remote sensing vehicle detection Open
Existing traffic flow modeling approaches typically rely on real-time observations, such as road sensors or GPS trajectories, which constrain their research scope and application scenarios. This study proposes a novel cross-spatiotemporal …
View article: Processability improvement and strength enhancement in laser powder bed fusion of AlMgZr and AlMgZr-Ti alloys
Processability improvement and strength enhancement in laser powder bed fusion of AlMgZr and AlMgZr-Ti alloys Open
The Al3(Ti, Zr) phase, which exhibits a lower formation enthalpy, was incorporated to improve the processability and strength of AlMgZr alloys fabricated by laser powder bed fusion (PBF-LB). The results confirmed that the crack-free AlMgZr…
View article: Acupuncture Action Due to Waves of Negative Potential Travelling in Interstitial Fluid
Acupuncture Action Due to Waves of Negative Potential Travelling in Interstitial Fluid Open
According to traditional Chinese medicine, meridians constitute an invisible network that connects body surface and viscera. Life-supporting substances, Qi and blood, circulate in meridians; acupuncture regulates meridian function. Since m…
View article: S- and N-Co-Doped Carbon-Nanoplate-Encased Ni Nanoparticles Derived from Dual-Ligand-Assembled Ni-MOFs as Efficient Electrocatalysts for the Oxygen Evolution Reaction
S- and N-Co-Doped Carbon-Nanoplate-Encased Ni Nanoparticles Derived from Dual-Ligand-Assembled Ni-MOFs as Efficient Electrocatalysts for the Oxygen Evolution Reaction Open
To achieve the “double carbon” goal, it is urgent to reform the energy system. The oxygen evolution reaction (OER) is a vital semi-reaction for many new energy-storage and conversion devices. Metal nanoparticles embedded in heteroatom-dope…
View article: Small Molecule Kinetic Stabilizers Reduce Amyloidogenicity of Free Light Chain Proteins of Diverse Sequences in λ Light Chain Amyloidosis
Small Molecule Kinetic Stabilizers Reduce Amyloidogenicity of Free Light Chain Proteins of Diverse Sequences in λ Light Chain Amyloidosis Open
In light chain amyloidosis (AL), clonal plasma cells produce free immunoglobulin light chain (FLC) proteins that are unstable and prone to misfolding, fragmentations, and aggregation, primarily affecting the heart and kidney. This instabil…
View article: Effects of In Situ TiB2 on the Microstructural Evolution, Mechanical Properties, and Friction Behavior of the Al-Si-Cu Alloys Processed by Laser Powder-Bed Fusion
Effects of In Situ TiB2 on the Microstructural Evolution, Mechanical Properties, and Friction Behavior of the Al-Si-Cu Alloys Processed by Laser Powder-Bed Fusion Open
In the present study, the densification behavior, microstructural evolution, mechanical properties, and friction behavior of a TiB2/Al8SiCu composite and Al8SiCu alloy manufactured by laser powder-bed fusion (PBF-LB) were systematically in…
View article: High-efficiency laminated luminescent solar concentrators based on carbon dots and nanorings
High-efficiency laminated luminescent solar concentrators based on carbon dots and nanorings Open
Creation of novel fluorescent nanomaterials with high photoluminescence quantum yield (PLQY) will lead to high-efficiency luminescent solar concentrators (LSCs). Herein, two kinds of carbon dots (CDs), e.g., blue and green emissive CDs and…
View article: Fluid Dynamics Investigation in a Cold Flow Model of Internal Recycle Quadruple Fluidized Bed Coal Pyrolyzer
Fluid Dynamics Investigation in a Cold Flow Model of Internal Recycle Quadruple Fluidized Bed Coal Pyrolyzer Open
Internal recycle quadruple fluidized bed pyrolyzer (IR-QFBP) consists of a dual fluidized bed pyrolyzer and a dual fluidized bed combustor and is proposed in this work. It is a new kind of efficient fluidized bed with high pyrolysis and en…
View article: Specific Recognition and Adsorption of Volatile Organic Compounds by Using MIL-125-Based Porous Fluorescence Probe Material
Specific Recognition and Adsorption of Volatile Organic Compounds by Using MIL-125-Based Porous Fluorescence Probe Material Open
The severity of the volatile organic compounds (VOCs) issue calls for effective detection and management of VOC materials. Metal-organic frameworks (MOFs) are organic-inorganic hybrid crystals with promising prospects in luminescent sensin…
View article: A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon Open
Hundreds of pathogenic variants of mitochondrial DNA (mtDNA) have been reported to cause mitochondrial diseases, which still lack effective treatments. It is a huge challenge to install these mutations one by one. We repurposed the DddA-de…
View article: Supplementary Methods, Figure Legends 1-5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Methods, Figure Legends 1-5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Methods, Figure Legends 1-5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies Open
Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
View article: Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Figure 4 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 4 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 4 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 5 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Figure 2 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 2 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 2 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies Open
Supplementary Methods, Figures 1-6, Tables A-C from Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
View article: Supplementary Figure 1 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 1 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 1 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Supplementary Figure 3 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Supplementary Figure 3 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Supplementary Figure 3 from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
View article: Data from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Data from Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity Open
Integrin α5β1 is overexpressed in tumor-associated stroma and cancer cells, and has been implicated in angiogenesis, tumor survival, and metastasis. Antibody-dependent cellular cytotoxicity (ADCC) by immune effector cells has been shown to…