Explanipedia

Confirming Rupture of Membranes with Intra-Amniotic Fluorescein Dye Test Open

Katherine Freedy, Sarah K. Dotters‐Katz, Bobby May, Sloane Mebane, Virginia Y. Watkins , et al. · 2025

We describe two patients presenting with preterm loss of fluid and inconclusive evaluations requiring further assessment. Patient 1 was a 41-year-old G3P1011 at 216/7 weeks; Patient 2 was a 22-year-old G2P1001 at 315/7 weeks. In both, pret…

Pregnancy and Delivery Care for a Patient With a HeartMate 3 Open

Sara I. Jones, H Acuff, R Best, Yen-Yen Gee, Sarah Snow , et al. · 2025

This represents the second reported HM3-supported pregnancy resulting in a live birth. Various barriers to care guided a shared anticoagulation plan, and no hemorrhagic or thrombotic complications occurred. Our intrapartum monitoring strat…

Dietary plant diversity predicts early life microbiome maturation Open

Torin McDonald, Ammara Aqeel, Ben Neubert, A. Bauer, Sharon Jiang , et al. · 2025

Summary Despite established links between the infant gut microbiome and health, how complementary feeding shapes colonization remains unclear. Using FoodSeq, a DNA-based dietary assessment technique, we surveyed food intake across 729 chil…

Dietary Plant Diversity Predicts Early Life Microbiome Maturation Open

Torin McDonald, Ammara Aqeel, Ben Neubert, A. Bauer, Sharon Jiang , et al. · 2025

Corrigendum: The Collection and Application of Autologous Amniotic Fluid to Cesarean Delivery Closure Open

Chad A. Grotegut, Kristin Weaver, Lena Fried, Sarah K. Dotters‐Katz, Jennifer B. Gilner · 2024

[This corrects the article DOI: 10.1055/a-2445-7954.].

The Collection and Application of Autologous Amniotic Fluid to Cesarean Delivery Closure Open

Chad A. Grotegut, Kristin Weaver, Lena Fried, Sarah K. Dotters‐Katz, Jennifer B. Gilner · 2024

Background Amniotic fluid and amnion membranes have been used in surgery specialties to improve wound healing and decrease surgical adhesion formation. Objective The objective was to determine if amniotic fluid could be collected at cesare…

CT-001, a novel fast-clearing factor VIIa, enhanced the hemostatic activity in postpartum samples Open

Derek S. Sim, Cornell R Mallari, Terry Hermiston, Daekyeong Bae, Sul Lee , et al. · 2023

The hemostatic system is upregulated to protect pregnant mothers from hemorrhage during childbirth. Studies of the details just before and after delivery, however, are lacking. Recombinant factor VIIa (rFVIIa) has recently been granted app…

PB1516 CT-001, a Novel Factor VIIa, Demonstrates Enhanced In Vitro Procoagulant Activity in Peripartum Patient Samples Open

Davin Sim, Terry Hermiston, Terrence K. Allen, D. H. Bae, Jennifer B. Gilner , et al. · 2023

Conclusion(s):Our study confirms that in cases of p-TMAs, the agreement between experts is very low.However, the low frequency of primary TMAs might explain the poor IRR found in our study.The new p-TMAs proposal showed the best IRR.

Placenta Accreta Spectrum Open

Brett D. Einerson, Jennifer B. Gilner, Lisa C. Zuckerwise · 2023

Placenta accreta spectrum (PAS) is one of the most dangerous conditions in pregnancy and is increasing in frequency. The risk of life-threatening bleeding is present throughout pregnancy but is particularly high at the time of delivery. Al…

Maternal Cardiovascular Morbidity Events Following Preeclampsia: A Retrospective Cohort Study Open

Marie‐Louise Meng, Zachary Frere, Matthew A. Fuller, Yi‐Ju Li, Ashraf S. Habib , et al. · 2022

BACKGROUND: Patients with preeclampsia are at high risk for long-term cardiovascular events, yet the short-term, acute cardiovascular complications that follow preeclampsia are understudied. The objective of this study was to compare the s…

Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface Open

Liheng Yang, Eleanor C. Semmes, Cristian Ovies, Christina Megli, Sallie R. Permar , et al. · 2022

Infections at the maternal-fetal interface can directly harm the fetus and induce complications that adversely impact pregnancy outcomes. Innate immune signaling by both fetal-derived placental trophoblasts and the maternal decidua must pr…

Transfusion Requirements with Hybrid Management of Placenta Accreta Spectrum Incorporating Targeted Embolization and a Selective Use of Delayed Hysterectomy Open

Luke A. Gatta, Jeremy M. Weber, Jennifer B. Gilner, Paula S. Lee, Chad A. Grotegut , et al. · 2022

Objective This study compares the number of units of red blood cells (RBCs) transfused in patients with placenta accreta spectrum (PAS) treated with or without a multidisciplinary algorithm that includes placental uterine arterial emboliza…

Author response: Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface Open

Liheng Yang, Eleanor C. Semmes, Cristian Ovies, Christina Megli, Sallie R. Permar , et al. · 2022

Symptomatic versus Asymptomatic COVID-19: Does It Impact Placental Vasculopathy? Open

Khaila Ramey-Collier, Amanda M. Craig, Allison Hall, Kristin Weaver, Sarahn M. Wheeler , et al. · 2022

COVID-19 and the Placenta: Impact of Maternal Disease Severity Open

Khaila Ramey-Collier, Amanda M. Craig, Allison Hall, Kristin Weaver, Sarahn M. Wheeler , et al. · 2022

Factors associated with cesarean section in patients with COVID Open

Amanda M. Craig, Khaila Ramey Collier, Kristin Weaver, Sarahn M. Wheeler, Jennifer B. Gilner , et al. · 2021

Serum sFlt-1/PIGF Ratio as a Biological Marker of Preeclampsia in Women with Rheumatic Disease Open

Kateena Addae-Konadu, Amanda M. Eudy, Megan E. B. Clowse, Jennifer B. Gilner · 2021

Preterm birth rates and race disparities pre and post COVID vaccination Open

Jennifer Cate, Amanda M. Craig, Miriam Estin, Kristin Weaver, Jennifer B. Gilner , et al. · 2021

Universal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing for Obstetric Inpatient Units Across the United States Open

Jennifer B. Gilner, Namita Kansal, Joseph Biggio, Shani Delaney, Chad A. Grotegut , et al. · 2021

Background The purpose of this study was to estimate prevalence of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among patients admitted to obstetric inpatient units throughout the United States as det…

Placental uterine artery embolization followed by delayed hysterectomy for placenta percreta: A case series Open

Luke A. Gatta, Paula S. Lee, Jennifer B. Gilner, Jeremy M. Weber, LaMani Adkins , et al. · 2021

Wnt2 Coordinates the Commitment of Mesoderm to Hematopoietic, Endothelial, and Cardiac Lineages in Embryoid Bodies Open

Hong Wang, Jennifer B. Gilner, Victoria L. Bautch, Da Zhi Wang, Brandon J. Wainwright , et al. · 2021

Our recent gene expression profiling analyses demonstrated that Wnt2 is highly expressed in Flk1(+) cells, which serve as common progenitors of endothelial cells, blood cells, and mural cells. In this report, we characterize the role of Wn…

Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface Open

Liheng Yang, Eleanor C. Semmes, Cristian Ovies, Christina Megli, Sallie R. Permar , et al. · 2021

Infections at the maternal-fetal interface can directly harm the fetus and induce complications that adversely impact pregnancy outcomes. Innate immune signaling by both fetal-derived placental trophoblasts and the maternal decidua must pr…

96 Preterm birth disparities at a single United States academic institution during the COVID pandemic Open

Amanda M. Craig, Sarah K. Dotters‐Katz, Kristin Weaver, Jennifer B. Gilner, Geeta K. Swamy , et al. · 2021

Universal SARS-CoV-2 Testing for Obstetric Inpatient Units Across the United States Open

Jennifer B. Gilner, Namita Kansal, Joseph Biggio, Shani Delaney, Chad A. Grotegut , et al. · 2021

Transfusion requirements with hybrid management of placenta accreta spectrum incorporating delayed hysterectomy: a retrospective study Open

Luke A. Gatta, Jeremy M. Weber, Jennifer B. Gilner, Paula Lee, Chad A. Grotegut , et al. · 2020

Acknowledgements:The authors would like to thank the contributions of Michael Miller, MD, Laura Havrilesky, MD MHSc, Sarah Ellestad, MD, Brita Boyd, Mustafa Bashir, MD, Megan Varvoutis, MD, and Isabel V. Rodriguez MD. The latter contribute…

Enrichment of therapeutic hematopoietic stem cell populations from embryonic stem cells Open

Jennifer B. Gilner · 2019

Embryonic Stem Cells (ESC) serve as a versatile and infinite source of primitive stem cells of any developmental lineage, made readily available for study or therapeutic application. The hematopoietic lineage in particular may benefit from…

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway Open

Sanjay Khandelwal, Joann Ravi, Lubica Rauova, Alexandra Johnson, Grace M. Lee , et al. · 2018

The mechanisms by which exposure to heparin initiates antibody responses in many, if not most, recipients are poorly understood. We recently demonstrated that antigenic platelet factor 4 (PF4)/heparin complexes activate complement in plasm…

Closed-Incision Negative-Pressure Therapy in Obese Patients Undergoing Cesarean Delivery: A Randomized Controlled Trial Open

Ravindu Gunatilake, Geeta K. Swamy, Leo R. Brancazio, Michael Smrtka, J. C. Thompson , et al. · 2017

Background Postcesarean wound morbidity is a costly complication of cesarean delivery for which preventative strategies remain understudied. Objective We compared surgical site occurrences (SSOs) in cesarean patients receiving closed-incis…

Novel pathogenic variants in <i>FOXP3</i> in fetuses with echogenic bowel and skin desquamation identified by ultrasound Open

Raymond J. Louie, Queenie K.‐G. Tan, Jennifer B. Gilner, R. Curtis Rogers, Noelle Younge , et al. · 2017

Immunodysregulation, Polyendocrinopathy, Enteropathy, X‐linked (IPEX) syndrome is a rare, X‐linked recessive disease that affects regulatory T cells (Tregs) resulting in diarrhea, enteropathy, eczema, and insulin‐dependent diabetes mellitu…

Chagas Disease Screening in Maternal Donors of Publicly Banked Umbilical Cord Blood, United States Open

James M. Edwards, Jennifer B. Gilner, José Ángel García Hernández, Joanne Kurtzberg, R. Phillips Heine · 2016

To assess patterns of Chagas disease, we reviewed results of screening umbilical cord blood from a US public cord blood bank during 2007-2014. Nineteen maternal donors tested positive for Trypanosoma cruzi parasites (0.04%). Because perina…

Jennifer B. Gilner YOU? Author Swipe