Jennifer J. Ormsbee
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View article: The CREBRF diabetes-protective <i>rs373863828-A</i> allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry
The CREBRF diabetes-protective <i>rs373863828-A</i> allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry Open
Aim The minor A allele of rs373863828 (CREBRF p.Arg457Gln) is associated with increased body mass index (BMI), but reduced risk of type 2 and gestational diabetes in Polynesian (Pacific peoples and Aotearoa New Zealand Māori) populations. …
View article: Variability in Estimated Modelled Insulin Secretion
Variability in Estimated Modelled Insulin Secretion Open
Background: The ability to measure insulin secretion from pancreatic beta cells and monitor glucose-insulin physiology is vital to current health needs. C-peptide has been used successfully as a surrogate for plasma insulin concentration. …
View article: The Impact of Exogenous Insulin Input on Calculating Hepatic Clearance Parameters
The Impact of Exogenous Insulin Input on Calculating Hepatic Clearance Parameters Open
Objective: Model-based metabolic tests require accurate identification of subject-specific parameters from measured assays. Insulin assays are used to identify insulin kinetics parameters, such as general and first-pass hepatic clearances.…
View article: Estimating endogenous glucose production during exercise using heart rate: implications for diabetes management
Estimating endogenous glucose production during exercise using heart rate: implications for diabetes management Open
Non-invasive, continuous Endogenous glucose production (EGP) estimation during exercise would help manage and automate insulin and glucose dosing during exercise, providing novel information to more effectively close the loop in managing g…
View article: Estimating Increased EGP During Stress Response in Critically Ill Patients
Estimating Increased EGP During Stress Response in Critically Ill Patients Open
Background: Stress-induced hyperglycemia is frequently experienced by critically ill patients and the use of glycemic control (GC) has been shown to improve patient outcomes. For model-based approaches to GC, it is important to understand …
A20 VITAMIN D SUPPLEMENTATION REDUCES THE OCCURRENCE OF COLORECTAL POLYPS IN HIGH-LATITUDE LOCATIONS Open
Background There is suggestive evidence for the role of vitamin D in the development of colorectal cancer (CRC). Furthermore, previous studies have observed associations with vitamin D supplementation and lower incidence of CRC. Due to hig…
View article: Estimating (unidentifiable) enhanced EGP in glycaemic control modelling: Dancing with minions of the Dark Lord
Estimating (unidentifiable) enhanced EGP in glycaemic control modelling: Dancing with minions of the Dark Lord Open
Critically ill patients frequently experience stress-induced hyperglycaemia. Glycaemic control
\n(GC) with insulin therapy can improve patient outcomes, but effective GC is not currently well achieved
\nin most critical care units. STAR is…