Explanipedia

In vivo translocator protein in females with autism spectrum disorder: a pilot study Open

Chieh-En Jane Tseng, Camila Canales, Rachel E.G. Marcus, Anjali Parmar, Baileigh G. Hightower , et al. · 2024

Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder Open

Stephen K. Siecinski, Stephanie N. Giamberardino, Marina Spanos, Annalise C. Hauser, Jason Gibson , et al. · 2023

Oxytocin (OT), the brain's most abundant neuropeptide, plays an important role in social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum disorder (ASD) have reported mixed results due in part to ASD's comp…

Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder Open

Stephen K. Siecinski, Stephanie N. Giamberardino, Marina Spanos, Annalise C. Hauser, Jason Gibson , et al. · 2022

Oxytocin (OT), the brain’s most abundant neuropeptide, plays an important role in social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum disorder (ASD) have reported mixed results due in part to ASD’s comp…

A randomized double-blind, placebo-controlled pilot trial of mirtazapine for anxiety in children and adolescents with autism spectrum disorder Open

Christopher J. McDougle, Robyn P. Thom, Caitlin Ravichandran, Michelle Palumbo, Laura C. Politte , et al. · 2022

Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder Open

Linmarie Sikich, Alexander Kolevzon, Bryan H. King, Christopher J. McDougle, Kevin Sanders , et al. · 2021

This placebo-controlled trial of intranasal oxytocin therapy in children and adolescents with autism spectrum disorder showed no significant between-group differences in the least-squares mean change from baseline on measures of social or …

[11C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder Open

Nicole R. Zürcher, Marco L. Loggia, Jennifer Mullett, Chieh-En Jane Tseng, Anisha Bhanot , et al. · 2020

Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD individuals, we measured the in vivo expression of the 18 kDa translocator protei…

Accuracy of self-reported history of autoimmune disease: A pilot study Open

Julia A. O’Rourke, Caitlin Ravichandran, Yamini J. Howe, Jennifer Mullett, Christopher J. Keary , et al. · 2019

Research associating the increased prevalence of familial autoimmunity with neuropsychiatric disorders is reliant upon the ascertainment of history of autoimmune diseases from relatives. To characterize the accuracy of self-report, we comp…

Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series Open

Francisca Valdes, Christopher J. Keary, Jennifer Mullett, Michelle Palumbo, Jessica L. Waxler , et al. · 2017

Digital stories as a tool for health promotion and youth engagement Open

Sarah Fletcher, Jennifer Mullett · 2016

Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome Open

Lauren M. McGrath, Joyce M. Oates, Yael G. Dai, Helen F. Dodd, Jessica L. Waxler , et al. · 2016

Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder Open

Lawrence David Scahill, James T. McCracken, Bryan H. King, Carol Rockhill, Bhavik Shah , et al. · 2015

Extended-release guanfacine appears to be safe and effective for reducing hyperactivity, impulsiveness, and distractibility in children with ASD.

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