Jennifer Schneider
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View article: Evaluation of pharmacokinetics of intravenous protein C concentrate in protein C deficiency: implications for treatment initiation and maintenance
Evaluation of pharmacokinetics of intravenous protein C concentrate in protein C deficiency: implications for treatment initiation and maintenance Open
View article: Psychosocial distress in rural palliative care: Preliminary longitudinal findings using the DADDS
Psychosocial distress in rural palliative care: Preliminary longitudinal findings using the DADDS Open
Objectives Palliative care enhances life, but rural Australia faces significant inequities, and psychosocial distress, an important yet often overlooked aspect, is under-recognized in these settings. This study examines how psychosocial di…
View article: Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer
Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer Open
Drug repurposing has potential to improve outcomes for high-grade serous ovarian cancer (HGSOC). Repurposing drugs with PARP family binding activity may produce cytotoxic effects through the multiple mechanisms of PARP including DNA repair…
View article: <scp>NSW</scp> cannabis medicines advisory service retrospective enquiry analysis to inform clinical guidance resource development
<span>NSW</span> cannabis medicines advisory service retrospective enquiry analysis to inform clinical guidance resource development Open
Background An innovative New South Wales government funded statewide Cannabis Medicines Advisory Service (CMAS) operated between January 2018 and June 2022. The service provided comprehensive patient‐specific and evidence‐based information…
View article: Administration of Levetiracetam via Subcutaneous Infusion for Seizure Control in the Palliative Care Setting: A Narrative Review
Administration of Levetiracetam via Subcutaneous Infusion for Seizure Control in the Palliative Care Setting: A Narrative Review Open
This narrative review aims to summarise the information available on the use of subcutaneous (SC) levetiracetam (LEV) in the adult palliative care setting using clinical texts, databases, journals, and grey literature. A search strategy ut…
View article: Comparison between a single- and a multi-point calibration method using LC-MS/MS for measurement of 5-fluorouracil in human plasma
Comparison between a single- and a multi-point calibration method using LC-MS/MS for measurement of 5-fluorouracil in human plasma Open
View article: Therapeutic drug monitoring in anticancer agents: perspectives of Australian medical oncologists
Therapeutic drug monitoring in anticancer agents: perspectives of Australian medical oncologists Open
Background In the development of anticancer agents for solid tumours, body surface area continues to be used to personalise dosing despite minimal evidence for its use over other dosing strategies. With the development of tyrosine kinase i…
View article: Antibiotics administered as continuous intravenous infusion over 24 hours by elastomeric devices to patients treated at home: a study of infusion efficiency
Antibiotics administered as continuous intravenous infusion over 24 hours by elastomeric devices to patients treated at home: a study of infusion efficiency Open
Background Elastomeric infusion devices or ‘Infusors’ are commonly used to administer 24‐h continuous intravenous infusions to hospital patients at home, a service which can increase hospital capacity. Aim This study sought to determine In…
View article: Phenotype versus genotype to optimize cancer dosing in the clinical setting—focus on 5‐fluorouracil and tyrosine kinase inhibitors
Phenotype versus genotype to optimize cancer dosing in the clinical setting—focus on 5‐fluorouracil and tyrosine kinase inhibitors Open
Cancer medicines often have narrow therapeutic windows; toxicity can be severe and sometimes fatal, but inadequate dose intensity reduces efficacy and survival. Determining the optimal dose for each patient is difficult, with body‐surface …
View article: Mapping the development of applied critical thinking skills in engineering technology majors
Mapping the development of applied critical thinking skills in engineering technology majors Open
Many universities have efforts related to infusing the teaching and learning of critical thinking, particularly for engineering, technology and computing related majors. This paper describes an applied critical thinking initiative at the R…
View article: Setting a Course for Student Success: Standards-Based Curriculum and Capacity-Building across Risk Prevention Management System Domains
Setting a Course for Student Success: Standards-Based Curriculum and Capacity-Building across Risk Prevention Management System Domains Open
Consensus standards aimed at risk mitigation and management have had an increasing presence in society, in response to incidents with significant societal impacts, as well as global efforts to enhance sustainable development and resilience…
View article: Paclitaxel and Therapeutic Drug Monitoring with Microsampling in Clinical Practice
Paclitaxel and Therapeutic Drug Monitoring with Microsampling in Clinical Practice Open
Paclitaxel is an anticancer agent efficacious in various tumors. There is large interindividual variability in drug plasma concentrations resulting in a wide variability in observed toxicity in patients. Studies have shown the time the con…
View article: PB1074 Population Pharmacokinetics of Subcutaneous Protein C Concentrate in Patients with Protein C Deficiency
PB1074 Population Pharmacokinetics of Subcutaneous Protein C Concentrate in Patients with Protein C Deficiency Open
Conclusion(s): All 13 patients had lower APC than the control group at all timepoints.This is in accordance with the increased thrombin generation in the PC group at 60 minutes and suggests that patients with PROC gene variants may have a …
View article: Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer
Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer Open
Background and Purpose: Drug repurposing has potential to improve the care for treatment resistant high-grade serous ovarian cancer (HGSOC). We hypothesised that broadly targeting PARP for drug repurposing would elicit cytotoxic responses …
View article: Impressum: Materialwiss. Werkstofftech. 9/2023
Impressum: Materialwiss. Werkstofftech. 9/2023 Open
View article: Evaluation of the Prescribing Skills Assessment implementation, performance and medical student experience in Australia and New Zealand
Evaluation of the Prescribing Skills Assessment implementation, performance and medical student experience in Australia and New Zealand Open
Aims The UK Prescribing Safety Assessment was modified for use in Australia and New Zealand (ANZ) as the Prescribing Skills Assessment (PSA). We investigated the implementation, student performance and acceptability of the ANZ PSA for fina…
View article: Table of Contents
Table of Contents Open
View article: A Comparison of Real and Virtual Laboratories for Pharmacy Teaching
A Comparison of Real and Virtual Laboratories for Pharmacy Teaching Open
New approaches to teaching and learning in the tertiary setting offer students flexibility for learning and, in a pandemic, suggests ways to provide learning when face-to-face delivery cannot be conducted. Courses that contain a hands-on l…
View article: <scp>NSW</scp> Cannabis Medicines Advisory Service preliminary survey results: enquirer perceptions and patient outcomes
<span>NSW</span> Cannabis Medicines Advisory Service preliminary survey results: enquirer perceptions and patient outcomes Open
Background In 2018, an innovative, State government‐funded cannabis medicines drug information service was established for health professionals in New South Wales (NSW). The NSW Cannabis Medicines Advisory Service (CMAS) provides expert cl…
View article: A framework for economic evaluation of therapeutic drug monitoring—guided dosing in oncology
A framework for economic evaluation of therapeutic drug monitoring—guided dosing in oncology Open
The standard approach for dose individualization of chemotherapy in the oncology setting has long been based on body surface area (BSA) as a measure of body size. However, for many anticancer drugs, administration of dosages based on BSA m…
View article: Overcoming barriers to implementing precision dosing with 5‐fluorouracil and capecitabine
Overcoming barriers to implementing precision dosing with 5‐fluorouracil and capecitabine Open
Despite advances in targeted cancer therapy, the fluoropyrimidines 5‐fluorouracil (5FU) and capecitabine continue to play an important role in oncology. Historically, dosing of these drugs has been based on body surface area. This approach…
View article: Clinic- and Hospital-Based Home Care, Outpatient Parenteral Antimicrobial Therapy (OPAT) and the Evolving Clinical Responsibilities of the Pharmacist
Clinic- and Hospital-Based Home Care, Outpatient Parenteral Antimicrobial Therapy (OPAT) and the Evolving Clinical Responsibilities of the Pharmacist Open
Clinic- and hospital-based home care describes models of care where services commonly associated with hospital inpatient care are provided at the patient’s home or in an outpatient or community-based clinic. Hospital in the Home (HITH), al…
View article: How Online Grading Feedback Might Benefit From a Grounding in Feminist Theory
How Online Grading Feedback Might Benefit From a Grounding in Feminist Theory Open
This chapter explores the application of feminist theory to online grading feedback processes in higher education. Christianakis describes teacher research as a feminist act. This chapter presents the argument that grading feedback can be …
View article: Depression screening in adults by pharmacists in the community: a systematic review
Depression screening in adults by pharmacists in the community: a systematic review Open
Background Improving the identification of depression in adults in primary care can produce clinical and economic benefits. Community Pharmacists may play a role in screening for depression. Objective To systematically review and evaluate …
View article: Student Acceptance of Using Augmented Reality Applications for Learning in Pharmacy: A Pilot Study
Student Acceptance of Using Augmented Reality Applications for Learning in Pharmacy: A Pilot Study Open
Creating engaging learning experiences that are easy to use and support the different learning requirements of university students is challenging. However, improvements in simulation technologies, such as augmented reality (AR) and virtual…
View article: Introducing Augmented Reality Technology to Enhance Learning in Pharmacy Education: A Pilot Study
Introducing Augmented Reality Technology to Enhance Learning in Pharmacy Education: A Pilot Study Open
There is increasing use of augmented reality (AR) technology, which combines the virtual and real world, in the tertiary education sector. AR enables flexibility in student learning, since this technology may be used in the face to face se…
View article: Association of Azithromycin Use With Cardiovascular Mortality
Association of Azithromycin Use With Cardiovascular Mortality Open
These findings suggest that outpatient azithromycin use was associated with an increased risk of cardiovascular death and noncardiovascular death. Causality cannot be established, particularly for noncardiovascular death, owing to the like…
View article: Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer
Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer Open
Cannabis has been used to relieve the symptoms of disease for thousands of years. However, social and political biases have limited effective interrogation of the potential benefits of cannabis and polarised public opinion. Further, the me…
View article: Barriers and Challenges in Performing Pharmacokinetic Studies to Inform Dosing in the Neonatal Population
Barriers and Challenges in Performing Pharmacokinetic Studies to Inform Dosing in the Neonatal Population Open
A number of barriers and challenges must be overcome in order to conduct the pharmacokinetic studies that are urgently needed to inform the selection and dosing of medication in neonates. However, overcoming these barriers can be difficult…
View article: On Matters of Feedback: Supporting the Online Grading Feedback Process with Web-Based, Collaborative Comment Banks
On Matters of Feedback: Supporting the Online Grading Feedback Process with Web-Based, Collaborative Comment Banks Open
This action research study describes how a web-based, feedback comment bank impacts online instructor efficacy as well as attitudes and perceptions associated with the online grading feedback process. Bandura’s work on individual self-effi…