Jennifer Wallace
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View article: CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia
CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia Open
Background We are conducting a Phase 1 clinical study to evaluate the safety and efficacy of escalating doses of autologous CD123-CAR T cells for pediatric patients with r/r CD123-positive AML or ALL. We previously reported (Naik et al, Bl…
View article: Mpox Cases Among Cisgender Women and Pregnant Persons — United States, May 11–November 7, 2022
Mpox Cases Among Cisgender Women and Pregnant Persons — United States, May 11–November 7, 2022 Open
Monkeypox (mpox) cases in the 2022 outbreak have primarily occurred among adult gay, bisexual, and other men who have sex with men (MSM); however, other populations have also been affected (1). To date, data on mpox in cisgender women and …
View article: Hellenism, philhellenism and classical reception: commemorating the 1821 revolution
Hellenism, philhellenism and classical reception: commemorating the 1821 revolution Open
The Greek Revolution of 1821–1829 mobilized the ideas of classical reception and Philhellenism developed over the previous century to appeal for international support for the war. These complicated ideas influenced the ways both Greeks and…
View article: Unlikely Rivals? Integrating Study Abroad into the Political Science Curriculum
Unlikely Rivals? Integrating Study Abroad into the Political Science Curriculum Open
As increasing globalization and political fragmentation highlight the need for students to expand their perspective as “global citizens,” one might expect political science students to be at the forefront of study abroad opportunities. Yet…
View article: The Gift of a Scholarship: The reflective accounts of scholarship recipients attending elite secondary schools in post-apartheid South Africa
The Gift of a Scholarship: The reflective accounts of scholarship recipients attending elite secondary schools in post-apartheid South Africa Open
This study investigates the experiences of scholarship students from historically disadvantaged communities who attend elite secondary schools in South Africa. Specifically, the study analyses the narrated accounts of a sample of former sc…
View article: A3 A PROOF-OF-CONCEPT, PHASE 2 CLINICAL TRIAL OF THE GI SAFETY OF A HYDROGEN SULFIDE-RELEASING ANTI-INFLAMMATORY DRUG (ATB-346)
A3 A PROOF-OF-CONCEPT, PHASE 2 CLINICAL TRIAL OF THE GI SAFETY OF A HYDROGEN SULFIDE-RELEASING ANTI-INFLAMMATORY DRUG (ATB-346) Open
BACKGROUND: Hydrogen sulfide (H(2)S) is a naturally occurring mediator produced by intestinal bacteria and various eukaryotic cells, which can exert protective and analgesic effects. ATB-346 is a H(2)S-releasing derivative of naproxen. In …
View article: Scotland: Wellbeing as Performance Management
Scotland: Wellbeing as Performance Management Open
Scotland was the first of the three devolved legislatures to embark on a wellbeing framework. The framework applies to all government departments and public bodies and aligns their activities by seeking improvements in 11 National Outcomes…
View article: Conclusions and Reflections
Conclusions and Reflections Open
In this concluding section, Wallace brings together the evidence and analysis to argue that the devolved legislatures are engaged in a complex process of policy diffusion and policy learning, among themselves and as part of the global move…
View article: Northern Ireland: Wellbeing as a Vision
Northern Ireland: Wellbeing as a Vision Open
Northern Ireland introduced its wellbeing framework through the draft Programme for Government in 2016. The approach aimed to create a shared vision for a post-conflict society and assist the power-sharing Executive in working together for…
View article: Introduction
Introduction Open
This chapter reviews the main philosophical debates pertaining to wellbeing, drawing a key distinction between personal wellbeing (living well) and societal wellbeing (living well together). The author explores how these translate into mea…
View article: Wales: Wellbeing as Sustainable Development
Wales: Wellbeing as Sustainable Development Open
Wales is at the global forefront on legislation on sustainable development, with the origins of this dating back to the original legislation on devolution in 1998. The most recent legislation, the Well-being of Future Generations Act 2015 …
View article: Wellbeing and Devolution
Wellbeing and Devolution Open
It has been over twenty years since the people of Scotland, Wales and Northern Ireland voted for devolution. Over that time, the devolved legislatures have established themselves and matured their approach to governance. At different times…
View article: Understanding Wellbeing and Devolution in Scotland, Wales and Northern Ireland
Understanding Wellbeing and Devolution in Scotland, Wales and Northern Ireland Open
Wallace provides an overview of the responsibilities of the devolved legislatures of Scotland, Wales and Northern Ireland and how these have developed over the past 20 years. Key facts on each jurisdiction are set out as are the trends in …
View article: Cross-Jurisdictional Analysis
Cross-Jurisdictional Analysis Open
This chapter explores the key components and characteristics of the wellbeing approaches taken by Scotland, Wales and Northern Ireland. Despite different origins, there are remarkable similarities between the approaches taken by the devolv…
View article: TRANSLATIONAL ASPECTS OF PLACE OF HYDROGEN SULFIDE-RELEASING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON THE TOMORROW’S LANDSCAPE FOR STRESSASSOCIATED DISORDERS
TRANSLATIONAL ASPECTS OF PLACE OF HYDROGEN SULFIDE-RELEASING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON THE TOMORROW’S LANDSCAPE FOR STRESSASSOCIATED DISORDERS Open
Non-steroidal anti-infl ammatory drugs (NSAID) are ones of the most widely prescribed drugs in medicine and up-to-date data have expanded their therapeutic role into complex biological processes such as oncogenesis, tissue repair, and diff…
View article: ALLIES OR ADVERSARIES? THE AUTHORITARIAN STATE AND CIVIL SOCIETY IN ENVIRONMENTAL GOVERNANCE: A CASE STUDY OF THE MEKONG DELTA
ALLIES OR ADVERSARIES? THE AUTHORITARIAN STATE AND CIVIL SOCIETY IN ENVIRONMENTAL GOVERNANCE: A CASE STUDY OF THE MEKONG DELTA Open
Natural resources are collective goods that the state has the authority and responsibility to protect from overuse and overexploitation. In order to achieve this protection, the state must rely on the actions of local actors, experts, and …