John S. Werner
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View article: Exploring the Impact of Generative AI ChatGPT on Critical Thinking in Higher Education: Passive AI-Directed Use or Human–AI Supported Collaboration?
Exploring the Impact of Generative AI ChatGPT on Critical Thinking in Higher Education: Passive AI-Directed Use or Human–AI Supported Collaboration? Open
Generative AI is weaving into the fabric of many human aspects through its transformative power to mimic human-generated content. It is not a mere technology; it functions as a generative virtual assistant, raising concerns about its impac…
View article: Training-induced changes in population receptive field properties in visual cortex: Impact of eccentric vision training on population receptive field properties and the crowding effect
Training-induced changes in population receptive field properties in visual cortex: Impact of eccentric vision training on population receptive field properties and the crowding effect Open
This study aimed to investigate the impact of eccentric-vision training on population receptive field (pRF) estimates to provide insights into brain plasticity processes driven by practice. Fifteen participants underwent functional magneti…
View article: Warm and cool reheated
Warm and cool reheated Open
Among more conventional perceptual attributes, such as hue brightness and saturation, color is universally assigned a value along a warm/cool dimension. The source of this aspect of color experience is uncertain and a subject of current de…
View article: High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography
High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography Open
This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical…
View article: Investigating the causes of stimulus-evoked changes in cone reflectance using a combined adaptive optics SLO-OCT system
Investigating the causes of stimulus-evoked changes in cone reflectance using a combined adaptive optics SLO-OCT system Open
In vivo functional imaging of human photoreceptors is an emerging field, with compelling potential applications in basic science, translational research, and clinical management of ophthalmic disease. Measurements of light-evoked changes i…
View article: Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light
Optoretinogram: optical measurement of human cone and rod photoreceptor responses to light Open
Noninvasive, objective measurement of rod function is as significant as that of cone function, and for retinal diseases such as retinitis pigmentosa and age-related macular degeneration, rod function may be a more sensitive biomarker of di…
View article: Adaptive Changes in Color Vision from Long-Term Filter Usage in Anomalous but Not Normal Trichromacy
Adaptive Changes in Color Vision from Long-Term Filter Usage in Anomalous but Not Normal Trichromacy Open
For over 150 years, spectrally selective filters have been proposed to improve the vision of observers with color vision deficiencies [1]. About 6% of males and <1% of females have anomalies in their gene arrays coded on the X chromosome t…
View article: COVID-19 Contact-Tracing Mobile Apps: Evaluation and Assessment for Decision Makers
COVID-19 Contact-Tracing Mobile Apps: Evaluation and Assessment for Decision Makers Open
A number of groups, from governments to non-profits, have quickly acted to innovate the contact-tracing process: they are designing, building, and launching contact-tracing apps in response to the COVID-19 crisis. A diverse range of approa…
View article: Apps Gone Rogue: Maintaining Personal Privacy in an Epidemic
Apps Gone Rogue: Maintaining Personal Privacy in an Epidemic Open
Containment, the key strategy in quickly halting an epidemic, requires rapid identification and quarantine of the infected individuals, determination of whom they have had close contact with in the previous days and weeks, and decontaminat…
View article: Age-Related Effects on Cross-Modal Duration Perception
Age-Related Effects on Cross-Modal Duration Perception Open
Reliable duration perception of external events is necessary to coordinate perception with action, precisely discriminate speech, and for other daily functions. Visual duration perception can be heavily influenced by concurrent auditory si…
View article: Suprathreshold contrast response in normal and anomalous trichromats
Suprathreshold contrast response in normal and anomalous trichromats Open
Maximum Likelihood Difference Scaling was used to measure suprathreshold contrast response difference scales for low-frequency Gabor patterns modulated along luminance and L-M color directions in normal, protanomalous, and deuteranomalous …
View article: Automated quantification of choriocapillaris anatomical features in ultrahigh-speed optical coherence tomography angiograms
Automated quantification of choriocapillaris anatomical features in ultrahigh-speed optical coherence tomography angiograms Open
In vivo visualization and quantification of choriocapillaris vascular anatomy is a fundamental step in understanding the relation between choriocapillaris degradation and atrophic retinopathies, including geographic atrophy. We describe a …
View article: Optoretinography: optical measurements of human cone and rod photoreceptor responses to light
Optoretinography: optical measurements of human cone and rod photoreceptor responses to light Open
Rods contribute crucially to human vision and their dysfunction precedes cones’ in several retinal diseases. Here we describe light-evoked, functional responses of human rods and cones, measured noninvasively using adaptive optics optical …
View article: Functional retinal imaging using adaptive optics swept-source OCT at 16 MHz
Functional retinal imaging using adaptive optics swept-source OCT at 16 MHz Open
Objective optical assessment of photoreceptor function may permit earlier diagnosis of retinal disease than current methods such as perimetry, electrophysiology, and clinical imaging. In this work, we describe an adaptive optics (AO) optic…
View article: Age-Related Effects on Cross-Modal Duration Perception: Supplementary Material
Age-Related Effects on Cross-Modal Duration Perception: Supplementary Material Open
Reliable duration perception of external events is necessary to coordinate perception with action, precisely discriminate speech, and for other daily functions. Visual duration perception can be heavily influenced by concurrent auditory si…
View article: Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging
Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging Open
Angiographic imaging of the human eye with optical coherence tomography (OCT) is becoming an increasingly important tool in the scientific investigation and clinical management of several blinding diseases, including age-related macular de…
View article: Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases
Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases Open
In retinal raster imaging modalities, fixational eye movements manifest as image warp, where the relative positions of the beam and retina change during the acquisition of single frames. To remove warp artifacts, strip-based registration m…
View article: Functional retinal imaging using adaptive optics swept-source OCT at 1.6MHz
Functional retinal imaging using adaptive optics swept-source OCT at 1.6MHz Open
Objective optical assessment of photoreceptor function may permit earlier diagnosis of retinal disease than current methods such as perimetry, electrophysiology, and clinical imaging. In this work, we describe an adaptive optics (AO) optic…
View article: Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscope
Volumetric imaging of rod and cone photoreceptor structure with a combined adaptive optics-optical coherence tomography-scanning laser ophthalmoscope Open
We have designed and implemented a dual-mode adaptive optics (AO) imaging system that combines spectral domain optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) for in vivo imaging of the human retina. The system s…
View article: Challenges and advantages in wide-field optical coherence tomography angiography imaging of the human retinal and choroidal vasculature at 1.7-MHz A-scan rate
Challenges and advantages in wide-field optical coherence tomography angiography imaging of the human retinal and choroidal vasculature at 1.7-MHz A-scan rate Open
We present noninvasive, three-dimensional, depth-resolved imaging of human retinal and choroidal blood circulation with a swept-source optical coherence tomography (OCT) system at 1065-nm center wavelength. Motion contrast OCT imaging was …
View article: The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography
The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography Open
Band 3 originates from a structure with axial extent similar to a single surface. Correlation with band 2 suggests an origin within the cone photoreceptor. These two observations indicate that band 3 corresponds predominantly to cone outer…
View article: Future developments - Adaptive Optics Applied to Glaucoma Imaging
Future developments - Adaptive Optics Applied to Glaucoma Imaging Open
Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) have substantially advanced ophthalmic imaging by improving the transversal resolution and axial resolution beyond that which can be achieved by the fundus camera. …