Jenny L. Wilson
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View article: Microglia Display Altered Spatial Morphology and Proteome After Stroke
Microglia Display Altered Spatial Morphology and Proteome After Stroke Open
Microglia are abundantly distributed throughout the central nervous system (CNS) to play critical roles in neural development and homeostasis, and act as immune sentinels to constantly monitor their surrounding neural environment. Given th…
View article: Intravenous Thrombolysis for Pediatric Acute Ischemic Stroke
Intravenous Thrombolysis for Pediatric Acute Ischemic Stroke Open
This cohort study examines function and safety outcomes among children with pediatric acute ischemic stroke treated with intravenous tissue plasminogen activator compared with standard care.
View article: Essential Components of Child Neurology Training: Program Director Consensus Recommendations
Essential Components of Child Neurology Training: Program Director Consensus Recommendations Open
Objective We aimed to develop a program director–derived model of essential components of child neurology residency training. Methods All 79 child neurology residency programs in the United States were invited to submit a block diagram wit…
View article: Microglia are prominent producers of inflammatory cytokines during the hyperacute phase of ischemic stroke
Microglia are prominent producers of inflammatory cytokines during the hyperacute phase of ischemic stroke Open
View article: Pediatric DYT-TOR1A dystonia presenting as functional neurological disorder: A case report
Pediatric DYT-TOR1A dystonia presenting as functional neurological disorder: A case report Open
View article: Consensus Clinical Management Guideline for <i>PLA2G6</i> -Associated Neurodegeneration (PLAN)
Consensus Clinical Management Guideline for <i>PLA2G6</i> -Associated Neurodegeneration (PLAN) Open
This clinical guideline provides recommendations for the evaluation and management of individuals with PLA2G6- associated neurodegeneration (PLAN). PLAN, a neurodegeneration with brain iron accumulation disorder, presents with infantile-on…
View article: Neurological Soft Signs at Presentation in Patients With Pediatric Acute-Onset Neuropsychiatric Syndrome
Neurological Soft Signs at Presentation in Patients With Pediatric Acute-Onset Neuropsychiatric Syndrome Open
Importance Studies of brain imaging and movements during rapid eye movement sleep indicate basal ganglia involvement in pediatric acute-onset neuropsychiatric syndrome (PANS). Characterizing neurological findings that commonly present amon…
View article: Eight Cases of Pediatric Acute-Onset Neuropsychiatric Syndrome with Inflammatory Bowel Disease: Immunologic Intersections
Eight Cases of Pediatric Acute-Onset Neuropsychiatric Syndrome with Inflammatory Bowel Disease: Immunologic Intersections Open
Introduction: Pediatric acute-onset neuropsychiatric syndrome (PANS) is an immune-mediated disease characterized by abrupt onset neurobehavioral changes. Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn’s disease…
View article: Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study
Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study Open
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View article: Prevalence of Neurological Soft Signs at Presentation in Pediatric Acute-Onset Neuropsychiatric Syndrome
Prevalence of Neurological Soft Signs at Presentation in Pediatric Acute-Onset Neuropsychiatric Syndrome Open
Importance Studies of brain imaging and movements during REM sleep indicate basal ganglia involvement in pediatric acute-onset neuropsychiatric syndrome (PANS). Characterizing neurological findings commonly present in patients with PANS co…
View article: Stroke Alters the Function of Enteric Neurons to Impair Smooth Muscle Relaxation and Dysregulates Gut Transit
Stroke Alters the Function of Enteric Neurons to Impair Smooth Muscle Relaxation and Dysregulates Gut Transit Open
Background Gut dysmotility is common after ischemic stroke, but the mechanism underlying this response is unknown. Under homeostasis, gut motility is regulated by the neurons of the enteric nervous system that control contractile/relaxatio…
View article: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and endoplasmic reticulum stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal re…
View article: Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Full text Figures and data Side by side Abstract eLife assessment eLife digest Introduction Results Discussion Materials and methods Data availability References Peer review Author response Article and author information Metrics Abstract P…
View article: Sympathetic-Mediated Intestinal Cell Death Contributes to Gut Barrier Impairment After Stroke
Sympathetic-Mediated Intestinal Cell Death Contributes to Gut Barrier Impairment After Stroke Open
View article: Tenecteplase in Pediatric Stroke: Ready or Not
Tenecteplase in Pediatric Stroke: Ready or Not Open
View article: Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Reviewer #1 (Public Review): Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Reviewer #1 (Public Review): Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Reviewer #2 (Public Review): Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Reviewer #2 (Public Review): Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and endoplasmic reticulum stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal re…
View article: Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays
Author Response: Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: Allelic strengths of encephalopathy-associated <i>UBA5</i> variants correlate between <i>in vivo</i> and <i>in vitro</i> assays
Allelic strengths of encephalopathy-associated <i>UBA5</i> variants correlate between <i>in vivo</i> and <i>in vitro</i> assays Open
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and ER stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder ch…
View article: The Role of Child Neurologists in the Management of Motor Disability in Cerebral Palsy: Establishing the Path Forward
The Role of Child Neurologists in the Management of Motor Disability in Cerebral Palsy: Establishing the Path Forward Open
View article: SIGnature Libraries: A roadmap for the formation of special interest group libraries
SIGnature Libraries: A roadmap for the formation of special interest group libraries Open
Objective “SIGnature Libraries” channel the dynamism of academic society‐based special interest groups (SIG) to systematically identify and provide user‐oriented access to essential literature for a subspecialty field in a manner that keep…
View article: Tenecteplase in Pediatric Stroke: Ready or Not
Tenecteplase in Pediatric Stroke: Ready or Not Open
View article: Brain‐associated innate leukocytes display diverse inflammatory states following experimental stroke
Brain‐associated innate leukocytes display diverse inflammatory states following experimental stroke Open
Previous studies investigating innate leukocyte recruitment into the brain after cerebral ischemia have shown conflicting results. Using distinct cell surface and intracellular markers, the current study evaluated the contributions of inna…
View article: Pediatric Stroke due to Thoracic Outlet Syndrome Treated with Thrombolysis and Thrombectomy: A Case Report
Pediatric Stroke due to Thoracic Outlet Syndrome Treated with Thrombolysis and Thrombectomy: A Case Report Open
Thoracic outlet syndrome (TOS) is a condition that results from the compression of neurovascular structures as they exit the thorax. Arterial ischemic stroke can occur in TOS due to retrograde embolism from the subclavian artery. We descri…
View article: International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic
International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic Open
Background: Data from the early pandemic revealed that 0.62% of children hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had an acute arterial ischemic stroke (AIS). In a larger cohort from June 2020 to Decem…
View article: Lung Imaging Reveals Stroke-Induced Impairment in Pulmonary Intravascular Neutrophil Function, a Response Exacerbated with Aging
Lung Imaging Reveals Stroke-Induced Impairment in Pulmonary Intravascular Neutrophil Function, a Response Exacerbated with Aging Open
In stroke patients, infection is a significant contributor to morbidity and mortality. Moreover, older stroke patients show an increased risk of developing stroke-associated infection, although the mechanisms underlying this increased susc…