Jens Köllermann
YOU?
Author Swipe
View article: Influence of PSA level at salvage radiotherapy on metastasis-free survival following radical prostatectomy
Influence of PSA level at salvage radiotherapy on metastasis-free survival following radical prostatectomy Open
View article: Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer Open
Current treatments for advanced prostate cancer (PCa) primarily target the androgen receptor (AR) pathway. However, the emergence of castration-resistant prostate cancer (CRPC) and resistance to AR pathway inhibitors (APPIs) remains ongoin…
View article: More micrometastases, more recurrence? The role of qPCR of PSA mRNA in lymph nodes during prostatectomy
More micrometastases, more recurrence? The role of qPCR of PSA mRNA in lymph nodes during prostatectomy Open
View article: Epigenetic profiling of prostate cancer reveals potential prognostic signatures
Epigenetic profiling of prostate cancer reveals potential prognostic signatures Open
View article: Histopathologic, Molecular, and Clinical Profiling of Lymphoepithelioma-like Carcinoma of the Bladder
Histopathologic, Molecular, and Clinical Profiling of Lymphoepithelioma-like Carcinoma of the Bladder Open
Lymphoepithelioma-like carcinoma of the bladder (LELC-B) is a rare histologic subtype characterized by strong immune cell (IC) infiltrates. A better prognosis and favorable response rates to immune checkpoint inhibitors have been described…
View article: Organ-confined pT2 ISUP4/5 vs. nonorgan confined pT3/4 ISUP2 vs. ISUP3 prostate cancer: Differences in biochemical recurrence-free survival after radical prostatectomy
Organ-confined pT2 ISUP4/5 vs. nonorgan confined pT3/4 ISUP2 vs. ISUP3 prostate cancer: Differences in biochemical recurrence-free survival after radical prostatectomy Open
View article: Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer Open
Current treatments for advanced prostate cancer (PCa) primarily target the androgen receptor (AR) pathway. However, the emergence of castration-resistant prostate cancer (CRPC) and resistance to AR pathway inhibitors (APSIs) remains ongoin…
View article: Transition from Transrectal to Transperineal MRI-Fusion Prostate Biopsy Does Not Comprise Detection Rates of Clinically Significant Prostate Cancer at a Tertiary Care Center
Transition from Transrectal to Transperineal MRI-Fusion Prostate Biopsy Does Not Comprise Detection Rates of Clinically Significant Prostate Cancer at a Tertiary Care Center Open
Background: A remarkable paradigm shift has emerged regarding the preferred prostate biopsy approach, favoring the transperineal (TP) over the transrectal (TR) approach due to the reduced risk of severe urinary tract infections. However, i…
View article: Fluoreszenzbasierte Konfokalmikroskopie – vollständige Digitalisierung der Pathologie
Fluoreszenzbasierte Konfokalmikroskopie – vollständige Digitalisierung der Pathologie Open
View article: Feasibility of Next-generation Sequencing of Liquid Biopsy (Circulating Tumor DNA) Samples and Tumor Tissue from Patients with Metastatic Prostate Cancer in a Real-world Clinical Setting in Germany
Feasibility of Next-generation Sequencing of Liquid Biopsy (Circulating Tumor DNA) Samples and Tumor Tissue from Patients with Metastatic Prostate Cancer in a Real-world Clinical Setting in Germany Open
Our study shows that genetic tests for both tumor tissue and blood samples results in higher rates of detection of BRCA1/2 gene alterations in patients with metastatic prostate cancer.
View article: Real-World Evidence of Tumor and Patient Characteristics and Survival with Avelumab Maintenance after Chemotherapy for Advanced and Metastatic Urothelial Carcinoma
Real-World Evidence of Tumor and Patient Characteristics and Survival with Avelumab Maintenance after Chemotherapy for Advanced and Metastatic Urothelial Carcinoma Open
Introduction: Despite the prospective randomized controlled JAVELIN Bladder 100 trial, no real-world evidence exists regarding tumor characteristics, adverse events (AEs), and survival of avelumab maintenance (AVM)-treated pa…
View article: Metastatic Squamous Cell Carcinoma of the Urinary Bladder: Urgent Call for New Therapies
Metastatic Squamous Cell Carcinoma of the Urinary Bladder: Urgent Call for New Therapies Open
Background: Squamous cell carcinoma (SCC) of the urinary bladder is the most common non-urothelial variant histology. Currently, upfront radical cystectomy is the gold standard for non-metastatic SCC of the bladder. However, …
View article: Comparison of peri- and intraoperative outcomes of open vs robotic-assisted partial nephrectomy for renal cell carcinoma: a propensity-matched analysis
Comparison of peri- and intraoperative outcomes of open vs robotic-assisted partial nephrectomy for renal cell carcinoma: a propensity-matched analysis Open
View article: Intraoperative Molecular Positron Emission Tomography Imaging for Intraoperative Assessment of Radical Prostatectomy Specimens
Intraoperative Molecular Positron Emission Tomography Imaging for Intraoperative Assessment of Radical Prostatectomy Specimens Open
In this report, we examined prostatectomy and lymphadenectomy specimens for suspicious positron emission tomography (PET) signals after preoperative tracer injection. It was found that in all cases, a good signal could be visualized, with …
View article: Impact of Age on Long-Term Urinary Continence after Robotic-Assisted Radical Prostatectomy
Impact of Age on Long-Term Urinary Continence after Robotic-Assisted Radical Prostatectomy Open
Aim and Objectives: We aimed to test the impact of age on long-term urinary continence (≥12 months) in patients undergoing robotic-assisted radical prostatectomy. Methods and Materials: We relied on an institutional tertiary-care database …
View article: Optimizing identification of consensus molecular subtypes in muscle-invasive bladder cancer: a comparison of two sequencing methods and gene sets using FFPE specimens
Optimizing identification of consensus molecular subtypes in muscle-invasive bladder cancer: a comparison of two sequencing methods and gene sets using FFPE specimens Open
View article: External Tertiary-Care-Hospital Validation of the Epidemiological SEER-Based Nomogram Predicting Downgrading in High-Risk Prostate Cancer Patients Treated with Radical Prostatectomy
External Tertiary-Care-Hospital Validation of the Epidemiological SEER-Based Nomogram Predicting Downgrading in High-Risk Prostate Cancer Patients Treated with Radical Prostatectomy Open
We aimed to externally validate the SEER-based nomogram used to predict downgrading in biopsied high-risk prostate cancer patients treated with radical prostatectomy (RP) in a contemporary European tertiary-care-hospital cohort. We relied …
View article: Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis
Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis Open
View article: Overexpression of KMT9α Is Associated with Aggressive Basal-like Muscle-Invasive Bladder Cancer
Overexpression of KMT9α Is Associated with Aggressive Basal-like Muscle-Invasive Bladder Cancer Open
Muscle-invasive bladder cancer (MIBC) is associated with limited response rates to systemic therapy leading to a significant risk of recurrence and death. A recently discovered histone methyltransferase KMT9, acts as an epigenetic regulato…
View article: Addendum: Sequencing of <i>BRCA1/2</i>-alterations using NGS-based technology: annotation as a challenge
Addendum: Sequencing of <i>BRCA1/2</i>-alterations using NGS-based technology: annotation as a challenge Open
View article: Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology Open
View article: Additional file 5 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Additional file 5 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology Open
Additional file 5: Feature values for PIN-4 stain.
View article: Differences in long-term continence rates between prostate cancer patients with extraprostatic vs. organ-confined disease undergoing robotic-assisted radical prostatectomy: An observational studys
Differences in long-term continence rates between prostate cancer patients with extraprostatic vs. organ-confined disease undergoing robotic-assisted radical prostatectomy: An observational studys Open
View article: Additional file 3 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Additional file 3 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology Open
Additional file 3: Feature values for ERG stain.
View article: Additional file 4 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Additional file 4 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology Open
Additional file 4: Feature values for H&E stain.
View article: Additional file 2 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Additional file 2 of Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology Open
Additional file 2: Classification labels (benign=0; malignant=1) for each tissue core.
View article: Abstracts des 74. Kongresses der Deutschen Gesellschaft für Urologie e. V.
Abstracts des 74. Kongresses der Deutschen Gesellschaft für Urologie e. V. Open
View article: The significance of the extent of tissue embedding for the detection of incidental prostate carcinoma on transurethral prostate resection material: the more, the better?
The significance of the extent of tissue embedding for the detection of incidental prostate carcinoma on transurethral prostate resection material: the more, the better? Open
View article: CK5/6 and GATA3 Defined Phenotypes of Muscle-Invasive Bladder Cancer: Impact in Adjuvant Chemotherapy and Molecular Subtyping of Negative Cases
CK5/6 and GATA3 Defined Phenotypes of Muscle-Invasive Bladder Cancer: Impact in Adjuvant Chemotherapy and Molecular Subtyping of Negative Cases Open
Introduction and Objective Identifying patients that benefit from cisplatin-based adjuvant chemotherapy is a major issue in the management of muscle-invasive bladder cancer (MIBC). The purpose of this study is to correlate “luminal” and “b…
View article: Full functional-length urethral sphincter- and neurovascular bundle preservation improves long-term continence rates after robotic-assisted radical prostatectomy
Full functional-length urethral sphincter- and neurovascular bundle preservation improves long-term continence rates after robotic-assisted radical prostatectomy Open