Jens Soukup
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View article: Acute Kidney Injury During Sepsis and Prognostic Role of Coexistent Chronic Heart Failure
Acute Kidney Injury During Sepsis and Prognostic Role of Coexistent Chronic Heart Failure Open
Background: The recently updated definition of sepsis considers pathophysiologic mechanisms to guide initial therapy. Clearly, generalized recommendations for sepsis therapy may be limited by pre-existing multimorbidity in addition to seps…
View article: Process optimisation: spinal versus general anaesthesia for endourological surgery. A randomised, controlled trial and machine-learning approach
Process optimisation: spinal versus general anaesthesia for endourological surgery. A randomised, controlled trial and machine-learning approach Open
Introduction Data concerning anaesthesia for endourology are rare, and options for it are numerous. Thus, identifying the optimal anaesthesia regimen remains challenging. With this study we aimed to provide the means for selecting optimal …
View article: The influence of different application patterns of propofol on the sedation courses during drug‐induced sleep endoscopy
The influence of different application patterns of propofol on the sedation courses during drug‐induced sleep endoscopy Open
Objective The course of sedation during drug‐induced sleep endoscopy (DISE) depends on the application pattern of the sedative drug. The depth of sedation should imitate light and deep sleep as well. Moreover, there should be as many breat…
View article: ICU- and ventilator-free days with isoflurane or propofol as a primary sedative – A post- hoc analysis of a randomized controlled trial
ICU- and ventilator-free days with isoflurane or propofol as a primary sedative – A post- hoc analysis of a randomized controlled trial Open
Isoflurane via the ACD was not associated with more VFD but with more ICU-FD and less concomitant sedative use.
View article: Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial Open
ICU patients sedated with sevoflurane >48 h may return to spontaneous breathing faster, while the quality of sedation is comparable to a propofol-based sedation regime. Sevoflurane might be considered to be safe for long-term sedation in t…
View article: Hemoadsorption in the critically ill—Final results of the International CytoSorb Registry
Hemoadsorption in the critically ill—Final results of the International CytoSorb Registry Open
The aim of the current paper is to summarize the results of the International CytoSorb Registry. Data were collected on patients of the intensive care unit. The primary endpoint was actual in-hospital mortality compared to the mortality pr…
View article: Therapeutic Plasma Exchanges in Combination with High-Dose Steroid-Induced Immunosuppression as an Ultima Ratio Therapy in Severe Coronavirus Disease 2019 (COVID-19): A Case-Series Report
Therapeutic Plasma Exchanges in Combination with High-Dose Steroid-Induced Immunosuppression as an Ultima Ratio Therapy in Severe Coronavirus Disease 2019 (COVID-19): A Case-Series Report Open
Agata Janikowska,1 Jens Soukup,2 Rainer U Pliquett,1 Rabah Abdel-Rahim1 1Department of Nephrology and Diabetology, Carl-Thiem Hospital, Cottbus, Germany; 2Clinic for Anesthesiology, Intensive Therapy and Palliative Medicine, Carl-Thiem Hos…
View article: Hemoadsorption in ‘Liver Indication’—Analysis of 109 Patients’ Data from the CytoSorb International Registry
Hemoadsorption in ‘Liver Indication’—Analysis of 109 Patients’ Data from the CytoSorb International Registry Open
Background: Our aim is to report the results of the ‘liver indication’ subset of patients in the CytoSorb International Registry. Methods: Structured data were recorded. Treatment characteristics and changes from T1 (start of hemoadsorptio…
View article: The influence of different application patterns on the sedation courses during drug induced sleep endoscopy
The influence of different application patterns on the sedation courses during drug induced sleep endoscopy Open
Background The course of sedation during drug induced sleep endoscopy (DISE) depends on the application pattern of the sedative drug. In order to perform a good evaluation of the upper airway a long transitional period between superficial …
View article: Adsorption therapy in critically ill with septic shock and acute kidney injury: a retrospective and prospective cohort study
Adsorption therapy in critically ill with septic shock and acute kidney injury: a retrospective and prospective cohort study Open
Background Haemoadsorption has been described as an effective way to control increased pro- and anti-inflammatory mediators (“cytokine storm”) in septic shock patients. No prospective or randomised clinical study has yet confirmed these re…