Min Jung Kim
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View article: Optimized prediction of breast cancer tumor microenvironment using MRI-based intratumoral and peritumoral radiomics: a prospective study
Optimized prediction of breast cancer tumor microenvironment using MRI-based intratumoral and peritumoral radiomics: a prospective study Open
Objective The tumor microenvironment (TME), composed of non-tumor elements such as stromal matrix and immune cells, plays a critical role in tumor progression, metastasis, and treatment response. This study aimed to investigate the associa…
View article: Integrative multi-omics of matched primary and liver metastatic colorectal cancer organoids identifies putative molecular targets
Integrative multi-omics of matched primary and liver metastatic colorectal cancer organoids identifies putative molecular targets Open
View article: Aortic Stenosis in End-Stage Renal Disease: Incidence, Prevalence, and Mortality in a National Korean Cohort
Aortic Stenosis in End-Stage Renal Disease: Incidence, Prevalence, and Mortality in a National Korean Cohort Open
Background/Objectives: Aortic stenosis (AS) is an increasingly recognized end-stage renal disease (ESRD) complication. This study aimed to identify AS incidence and prevalence in Korean patients with ESRD, assess the effect of AS on all-ca…
View article: GenX induces neuroinflammatory responses in BV2 microglial cells through mTOR signaling-mediated inhibition of autophagy
GenX induces neuroinflammatory responses in BV2 microglial cells through mTOR signaling-mediated inhibition of autophagy Open
Hexafluoropropylene oxide dimer acid (HFPO-DA), commonly known as GenX, can traverse the blood-brain barrier and infiltrate brain tissue, leading to nervous system damage that primarily manifests as neuroinflammation and neuronal apoptosis…
View article: Comparative risk of retinal microvascular disorders in patients with gout initiating febuxostat versus allopurinol: a population-based cohort study
Comparative risk of retinal microvascular disorders in patients with gout initiating febuxostat versus allopurinol: a population-based cohort study Open
Despite recent accumulation on cardiovascular (CV) safety data on xanthine oxidase inhibitors (XOIs) among gout patients, assessment has been largely limited to macro- than micro-vascular disorders, prompting the investigation on the latte…
View article: Factors associated with matching into highly ranked U.S. neurosurgical residencies
Factors associated with matching into highly ranked U.S. neurosurgical residencies Open
Highly ranked neurosurgery residencies consistently favor graduates of highly ranked medical schools who demonstrate strong research productivity. Each incremental h-index point raises top program match likelihood by 12-18 %. In contrast, …
View article: Electrochemical Microneedles for Real-Time Monitoring in Interstitial Fluid: Emerging Technologies and Future Directions
Electrochemical Microneedles for Real-Time Monitoring in Interstitial Fluid: Emerging Technologies and Future Directions Open
Conventional blood-based detection methods for biomarkers and analytes face significant limitations, including complex processing, variability in blood components, and the inability to provide continuous monitoring. These challenges hinder…
View article: Correction: Scientific validation of traditionally used omija (Schisandra chinensis) extract mixture for postprandial glucose regulation
Correction: Scientific validation of traditionally used omija (Schisandra chinensis) extract mixture for postprandial glucose regulation Open
View article: Perfluorooctanoic acid (PFOA) activates astrogliosis-associated neuroinflammation through ER stress-autophagy axis
Perfluorooctanoic acid (PFOA) activates astrogliosis-associated neuroinflammation through ER stress-autophagy axis Open
Perfluorooctanoic acid (PFOA), a perfluoroalkyl acid, induces neuroinflammation. However, present understanding regarding its fundamental role in neuroinflammation remains limited. Therefore, in this study, we aimed to clarify the potentia…
View article: Innovative Discrete Multi-Wavelength Near-Infrared Spectroscopic (DMW-NIRS) Imaging for Rapid Breast Lesion Differentiation: Feasibility Study
Innovative Discrete Multi-Wavelength Near-Infrared Spectroscopic (DMW-NIRS) Imaging for Rapid Breast Lesion Differentiation: Feasibility Study Open
Background/Objectives: This study evaluated the role of a discrete multi-wavelength near-infrared spectroscopic (DMW-NIRS) imaging device for rapid breast lesion differentiation. Methods: A total of 62 women (mean age, 49.9 years) with ult…
View article: Scientific validation of traditionally used omija (Schisandra chinensis) extract mixture for postprandial glucose regulation
Scientific validation of traditionally used omija (Schisandra chinensis) extract mixture for postprandial glucose regulation Open
According to Dongeuibogam (東醫寶鑑), a UNESCO Memory of the World-registered medical text, Omigalsu (五味喝水) was a traditional Korean beverage formulated from Schisandra chinensis (Turcz.) Baill. (Omija, Schisandra) extract and soybean. It was …
View article: Use of electronic medical records in simulated nursing education and its educational outcomes: A scoping review
Use of electronic medical records in simulated nursing education and its educational outcomes: A scoping review Open
View article: Novel function of TREK-1 in regulating adipocyte differentiation and lipid accumulation
Novel function of TREK-1 in regulating adipocyte differentiation and lipid accumulation Open
K2P (two-pore domain potassium) channels, a diversified class of K + -selective ion channels, have been found to affect a wide range of physiological processes in the body. Despite their established significance in regulating proliferation…
View article: Ultrafast Switching and High-Endurance Nonvolatile Memory Using Ferroelectric Janus Monolayers
Ultrafast Switching and High-Endurance Nonvolatile Memory Using Ferroelectric Janus Monolayers Open
The discovery of two-dimensional semiconducting ferroelectric (SFe) materials marks a pivotal step toward the commercialization of ferroelectric random-access memory. Despite their potential as ideal platforms for ultrafast switching and u…
View article: High cellular prion protein expression in cholangiocarcinoma: A marker for early postoperative recurrence and unfavorable prognosis
High cellular prion protein expression in cholangiocarcinoma: A marker for early postoperative recurrence and unfavorable prognosis Open
BACKGROUND The cellular prion protein (PrPC), traditionally associated with neurodegenerative disorders, plays an important role in cancer progression and metastasis by inhibiting apoptosis. AIM To investigate the influence of PrPC express…
View article: Interactions of the maternal microbiome with diet, stress, and infection influence fetal development
Interactions of the maternal microbiome with diet, stress, and infection influence fetal development Open
Humans and other animals contain multitudes of microorganisms including bacteria, fungi, and viruses, which make up a diverse microbiome. Across body sites including skin, gastrointestinal tract, and oral cavity there are distinct microbia…
View article: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron Open
View article: Chestnut (Castanea crenata S. et Z.) inner shell-A by-product promotes anti-obesity by regulating adipogenesis and lipogenesis-related genes and the AMPK/ACC signaling pathway in high-fat diet-induced obese mice
Chestnut (Castanea crenata S. et Z.) inner shell-A by-product promotes anti-obesity by regulating adipogenesis and lipogenesis-related genes and the AMPK/ACC signaling pathway in high-fat diet-induced obese mice Open
View article: Brief summary of the regulatory frameworks of regenerative medicine therapies
Brief summary of the regulatory frameworks of regenerative medicine therapies Open
The rapid advancements in regenerative medicine (RM), including cell therapies, gene therapies, tissue-engineered products, and combined RM advanced therapies, require the development of regulatory frameworks. The global landscape of regul…
View article: Age-Dependent Performance of Anthropometric Thresholds for Clinical Obesity: Validation of the Lancet Commission Framework in Korean Adults
Age-Dependent Performance of Anthropometric Thresholds for Clinical Obesity: Validation of the Lancet Commission Framework in Korean Adults Open
View article: In Vivo Conductivity of Normal Fibroglandular Tissue Using MR Electrical Properties Tomography: A Comparison With Apparent Diffusion Coefficient
In Vivo Conductivity of Normal Fibroglandular Tissue Using MR Electrical Properties Tomography: A Comparison With Apparent Diffusion Coefficient Open
View article: Integrative Multi-Omics of Matched Primary and Liver Metastatic Colorectal Cancer Organoids Identifies Putative Molecular Targets
Integrative Multi-Omics of Matched Primary and Liver Metastatic Colorectal Cancer Organoids Identifies Putative Molecular Targets Open
View article: Cambodian American Parents Perspectives and Knowledge of Special Education Supports for their Children with Disabilities
Cambodian American Parents Perspectives and Knowledge of Special Education Supports for their Children with Disabilities Open
Knowledge of the special education process has been found to enhance parental involvement with collateral effects of positive school outcomes for students with disabilities. Although research on immigrant families with children with disabi…
View article: Long-term weight patterns and physical activity in gallstones
Long-term weight patterns and physical activity in gallstones Open
While obesity, rapid weight loss, and sedentary lifestyles contribute to gallstones, the impacts of long-term weight patterns and physical activity on gallstone risk have not been extensively studied at the population level. Using Korea's …
View article: Effects of simulated microgravity on colorectal cancer organoids growth and drug response
Effects of simulated microgravity on colorectal cancer organoids growth and drug response Open
Cellular and molecular dynamics of human cells are constantly affected by gravity. Alteration of the gravitational force disturbs the cellular equilibrium, which might modify physiological and molecular characteristics. Nevertheless, biolo…
View article: The Impact of Pembrolizumab as a Salvage Therapy Based on HER2 Expression in Advanced Gastric Cancer
The Impact of Pembrolizumab as a Salvage Therapy Based on HER2 Expression in Advanced Gastric Cancer Open
Immune checkpoint inhibitors (ICIs) are used as salvage treatments for advanced gastric cancer (AGC) regardless of HER2 status. This study assessed the efficacy of ICIs based on HER2 expression in AGC patients who received pembrolizumab as…
View article: Second breast cancer following negative breast MRI: Analysis by interval from surgery and risk factors
Second breast cancer following negative breast MRI: Analysis by interval from surgery and risk factors Open
Objectives This study aims to compare outcomes following a negative surveillance MRI study by surgery-MRI interval and investigate factors associated with second breast cancers in women with a personal history of breast cancer (PHBC). Meth…
View article: Are sporadic colorectal cancers in young patients distinct from those in elderly patients?
Are sporadic colorectal cancers in young patients distinct from those in elderly patients? Open
Aim The aim of this study was to compare the clinicopathological and oncological characteristics of sporadic colorectal cancer (CRC) between young and elderly patients without any genetic mutations that cause hereditary CRC. Method In this…
View article: Determination of the appropriate chemotherapy for patients aged 80 years or older with diffuse large B cell lymphoma
Determination of the appropriate chemotherapy for patients aged 80 years or older with diffuse large B cell lymphoma Open
The optimal chemotherapy for newly diagnosed (ND) diffuse large B-cell lymphoma (DLBCL) in patients aged 80 years or older has not been conclusively determined. Due to the expected toxicities and comorbidities in this age group, intensifyi…
View article: Liquid Chromatography/Tandem Mass Spectrometry Analysis of Sophora flavescens Aiton and Protective Effects against Alcohol-Induced Liver Injury and Oxidative Stress in Mice
Liquid Chromatography/Tandem Mass Spectrometry Analysis of Sophora flavescens Aiton and Protective Effects against Alcohol-Induced Liver Injury and Oxidative Stress in Mice Open
In this study, we investigated the hepatoprotective effects of an ethanol extract of Sophora flavescens Aiton (ESF) on an alcohol-induced liver disease mouse model. Alcoholic liver disease (ALD) was caused by the administration of ethanol …