Jeremiah J. Peiffer
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View article: Bilateral blood flow restriction of the legs worsens acute walking balance of older adults – a full factorial randomised experiment
Bilateral blood flow restriction of the legs worsens acute walking balance of older adults – a full factorial randomised experiment Open
Our findings suggest that BFR results in poorer acute walking balance, with a dose-response relationship for cuff pressure. Supervised walking trials are warranted to further assess the safety of BFR training in community settings and whet…
View article: Prescribing Blood Flow‐Restricted Cycling Using Rating of Perceived Exertion Balances the Physiological and Perceptual Demands in Young Healthy Adults
Prescribing Blood Flow‐Restricted Cycling Using Rating of Perceived Exertion Balances the Physiological and Perceptual Demands in Young Healthy Adults Open
To compare the physiological and perceptual responses during fixed‐power and perceptually regulated cycling, both without and with blood flow restriction (CON PWR , BFR PWR , CON RPE and BFR RPE ). Twelve recreationally active men cycled f…
View article: Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes
Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes Open
Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an ex…
View article: Longitudinal associations between self‐reported exercise levels and cognition in ADAD
Longitudinal associations between self‐reported exercise levels and cognition in ADAD Open
INTRODUCTION This study examined longitudinal associations between self‐reported exercise and cognition, with moderation by sex, in individuals with autosomal dominant Alzheimer's disease (ADAD) mutations. We also examined whether changes …
View article: Effects of HIIT in Cool and Hot on Temperate Performance and Physiological Response in Trained Cyclists
Effects of HIIT in Cool and Hot on Temperate Performance and Physiological Response in Trained Cyclists Open
Boynton, JR, Peiffer, JJ, and Abbiss, CR. Effects of HIIT in cool and hot on temperate performance and physiological response in trained cyclists. J Strength Cond Res 39(3): e485–e495, 2025—This study investigated cardiopulmonary responses…
View article: Systemic hypoxia has a larger effect on reducing the external load at lower exercise intensity during heart rate clamped cycling
Systemic hypoxia has a larger effect on reducing the external load at lower exercise intensity during heart rate clamped cycling Open
The effects of acute hypoxic exposure on mechanical output and internal responses during cycling with heart rate (HR) clamped at lactate thresholds 1 and 2 (LT1 and LT2, respectively) were investigated. On separate days, 12 trained males c…
View article: Longitudinal associations between self‐reported exercise levels and Alzheimer’s related biomarkers in Autosomal Dominant Alzheimer’s Disease
Longitudinal associations between self‐reported exercise levels and Alzheimer’s related biomarkers in Autosomal Dominant Alzheimer’s Disease Open
Background Accumulating evidence indicates exercise may delay or prevent the onset of Alzheimer’s disease (AD). To our knowledge, no study has investigated the longitudinal impact of exercise on AD‐related biomarkers in individuals with Au…
View article: Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease Open
INTRODUCTION We investigated longitudinal associations between self‐reported exercise and Alzheimer's disease (AD)‐related biomarkers in individuals with autosomal dominant AD (ADAD) mutations. METHODS Participants were 308 ADAD mutation c…
View article: Exploration of Alzheimer's disease-related gene expression following high-intensity and moderate-intensity exercise interventions
Exploration of Alzheimer's disease-related gene expression following high-intensity and moderate-intensity exercise interventions Open
Exercise does not change AD-related gene expression in cognitively unimpaired older adults. Several gene expression targets have been identified for further study.
View article: Estimating cardiorespiratory fitness in older adults using the international physical activity questionnaire
Estimating cardiorespiratory fitness in older adults using the international physical activity questionnaire Open
Introduction Non-exercise estimates of cardiorespiratory fitness hold great utility for epidemiological research and clinical practice. Older adults may yield the greatest benefit from fitness estimates due to limited capacity to undergo s…
View article: Automatic adjustment of cycle ergometer power output to accurately clamp heart rate
Automatic adjustment of cycle ergometer power output to accurately clamp heart rate Open
We assessed the accuracy and inter-sessional reliability of traditional (manual) compared to automatic (AutoHR) heart rate (HR) clamping methods during submaximal intensity continuous cycling. On separate occasions, thirteen males cycled a…
View article: Continuous blood flow restriction during repeated‐sprint exercise increases peripheral but not systemic physiological and perceptual demands
Continuous blood flow restriction during repeated‐sprint exercise increases peripheral but not systemic physiological and perceptual demands Open
This study examined the impact of continuous blood flow restriction (BFR) during repeated‐sprint exercise (RSE) on acute performance, peripheral, systemic physiological, and perceptual responses. In a randomized crossover design, 26 adult …
View article: The impact of exercise on blood-based biomarkers of Alzheimer’s disease in cognitively unimpaired older adults
The impact of exercise on blood-based biomarkers of Alzheimer’s disease in cognitively unimpaired older adults Open
View article: A comparison of physiological and perceptual responses to fixed‐power and perceptually regulated cycling with and without blood flow restriction in trained cyclists
A comparison of physiological and perceptual responses to fixed‐power and perceptually regulated cycling with and without blood flow restriction in trained cyclists Open
This study compared physiological and perceptual responses between cycling prescribed using fixed‐power (PWR) and fixed rating of perceived exertion (RPE), when performed with blood flow restricted (BFR PWR and BFR RPE ) and unrestricted (…
View article: Can period-related symptoms predict menstrual manipulation among Australian female cyclists?
Can period-related symptoms predict menstrual manipulation among Australian female cyclists? Open
This study explored the extent of menstrual manipulation and its associated impact on period-related symptoms and training disruptions in Australian Female Cyclists. 205 female cyclists, from recreational to elite level, participated in an…
View article: Recovery following exercise-induced fatigue: Influence of a single heart rate clamped cycling session under systemic hypoxia
Recovery following exercise-induced fatigue: Influence of a single heart rate clamped cycling session under systemic hypoxia Open
We investigated whether a single heart rate clamped cycling session under systemic hypoxia affects the recovery of physical and psycho-physiological responses from residual fatigue compared to normoxia. On separate occasions, twelve traine…
View article: The Improvement in Exercise Performance during Reduced Muscle Mass Exercise is Associated with an Increase in Femoral Blood Flow in Older and Younger Endurance-Trained Athletes
The Improvement in Exercise Performance during Reduced Muscle Mass Exercise is Associated with an Increase in Femoral Blood Flow in Older and Younger Endurance-Trained Athletes Open
This study investigated whether the improved performance observed with maximal self-paced single-leg (SL), compared with double-leg (DL) cycling, is associated with enhanced femoral blood flow and/or altered tissue oxygenation. The hyperae…
View article: Dose-response effects of exercise on mental health in community-dwelling older adults: Exploration of genetic moderators
Dose-response effects of exercise on mental health in community-dwelling older adults: Exploration of genetic moderators Open
View article: The influence of baseline sleep on exercise‐induced cognitive change in older adults: A randomised clinical trial
The influence of baseline sleep on exercise‐induced cognitive change in older adults: A randomised clinical trial Open
Background Observational studies consistently demonstrate that physical activity is associated with enhanced cognitive function and reduced risk for dementia. However, there remains significant heterogeneity in study findings regarding the…
View article: The intensity of a resistance exercise session can be quantified by the work rate of exercise
The intensity of a resistance exercise session can be quantified by the work rate of exercise Open
Purpose Athletes regularly perform resistance training, yet it is unknown how best to monitor its intensity. This study compared different resistance exercise intensity metrics to determine their sensitivity to manipulating work rate (via …
View article: The effect of acute exercise on objectively measured sleep and cognition in older adults
The effect of acute exercise on objectively measured sleep and cognition in older adults Open
Background Exercise can improve cognition in aging, however it is unclear how exercise influences cognition, and sleep may partially explain this association. The current study aimed to investigate whether objectively measured sleep mediat…
View article: Physical characteristics of male elite wheelchair basketball athletes prior to the Paralympic Games
Physical characteristics of male elite wheelchair basketball athletes prior to the Paralympic Games Open
View article: The influence of baseline sleep on exercise‐induced cognitive change in cognitively unimpaired older adults: A randomised clinical trial
The influence of baseline sleep on exercise‐induced cognitive change in cognitively unimpaired older adults: A randomised clinical trial Open
Objectives Observational studies consistently demonstrate that physical activity is associated with elevated cognitive function, however, there remains significant heterogeneity in cognitive outcomes from randomized exercise interventions.…
View article: Acute Performance, Physiological and Perceptual Responses to Repeated-Sprint Exercise with Continuous or Intermittent Blood Flow Restriction
Acute Performance, Physiological and Perceptual Responses to Repeated-Sprint Exercise with Continuous or Intermittent Blood Flow Restriction Open
View article: Maintenance of internal load despite a stepwise reduction in external load during moderate intensity heart rate clamped cycling with acute graded normobaric hypoxia in males
Maintenance of internal load despite a stepwise reduction in external load during moderate intensity heart rate clamped cycling with acute graded normobaric hypoxia in males Open
Increasing hypoxia severity reduces cycling power output and arterial oxygen saturation in a stepwise fashion without affecting exercise responses between sea-level and simulated altitudes up to 3500 m despite breathing difficulty being el…
View article: The velocity of resistance exercise does not accurately assess repetitions‐in‐reserve
The velocity of resistance exercise does not accurately assess repetitions‐in‐reserve Open
This study assessed the reliability of mean concentric bar velocity from 3‐ to 0‐repetitions in reserve (RIR) across four sets in different exercises (bench press and prone row) and with different loads (60 and 80% 1‐repetition maximum; 1R…
View article: Automatic heart rate clamp: A practical tool to control internal and external training loads during aerobic exercise
Automatic heart rate clamp: A practical tool to control internal and external training loads during aerobic exercise Open
OPINION article Front. Physiol., 07 April 2023Sec. Exercise Physiology Volume 14 - 2023 | https://doi.org/10.3389/fphys.2023.1170105
View article: Blood flow restricted walking alters gait kinematics
Blood flow restricted walking alters gait kinematics Open
This study investigated the impact of blood flow restriction (BFR) during treadmill walking on gait kinematics. Twenty‐one participants completed one familiarisation and four experimental sessions, including two walking speeds (moderate [5…
View article: Exercise-induced responses in matrix metalloproteinases and osteopontin are not moderated by exercise format in males with overweight or obesity
Exercise-induced responses in matrix metalloproteinases and osteopontin are not moderated by exercise format in males with overweight or obesity Open
View article: Load-velocity relationships and predicted maximal strength: A systematic review of the validity and reliability of current methods
Load-velocity relationships and predicted maximal strength: A systematic review of the validity and reliability of current methods Open
Maximal strength can be predicted from the load-velocity relationship (LVR), although it is important to understand methodological approaches which ensure the validity and reliability of these strength predictions. The aim of this systemat…