Jeremy Deisch
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View article: Intracholecystic papillary neoplasm in a child: A case report
Intracholecystic papillary neoplasm in a child: A case report Open
Introduction: Gallbladder (GB) cancer is a well-studied neoplasia that occurs within the mucosal lining of the gallbladder. More recently, a pre-invasive lesion of the gallbladder, known as intracholecystic papillary neoplasm (ICPN), has b…
View article: Artificial intelligence-based epigenomic, transcriptomic and histologic signatures of tobacco use in oral squamous cell carcinoma
Artificial intelligence-based epigenomic, transcriptomic and histologic signatures of tobacco use in oral squamous cell carcinoma Open
Oral squamous cell carcinoma (OSCC) biomarker studies rarely employ multi-omic biomarker strategies and pertinent clinicopathologic characteristics to predict mortality. In this study we determine for the first time a combined epigenetic, …
View article: Unusual presentation of glioblastoma in the brainstem: a case report of a diffuse pontine glioblastoma multiforme and surgical management
Unusual presentation of glioblastoma in the brainstem: a case report of a diffuse pontine glioblastoma multiforme and surgical management Open
Diffuse pontine glioblastoma multiforme is a rare subtype of glioblastoma associated with a poor prognosis. In this case report, we present a unique case of diffuse primary pontine glioblastoma multiforme in a patient without any supratent…
View article: Correction: Neuropathologic findings in a patient with Parry-Romberg syndrome: active cerebral vasculitis and brain injury
Correction: Neuropathologic findings in a patient with Parry-Romberg syndrome: active cerebral vasculitis and brain injury Open
View article: Neuropathologic findings in a patient with Parry-Romberg syndrome: active cerebral vasculitis and brain injury
Neuropathologic findings in a patient with Parry-Romberg syndrome: active cerebral vasculitis and brain injury Open
Purpose Parry-Romberg syndrome (PRS) is a rare disorder characterized by slowly progressive hemifacial atrophy. Although the underlying etiology is unknown, proposed disease mechanisms which include autoimmune, infection, trauma, and other…
View article: Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of <i>OLIG2</i> in Adult Gliomas
Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of <i>OLIG2</i> in Adult Gliomas Open
Isocitrate dehydrogenase (IDH) mutant gliomas are associated with a better prognosis in comparison to adult IDH wild-type glioma and glioma-CpG island methylator phenotypes. Although OLIG2 is mainly expressed in oligodendrocytes in normal …
View article: 72‐year‐old man with right homonymous hemianopia and gait instability
72‐year‐old man with right homonymous hemianopia and gait instability Open
An elderly man presented with right homonymous hemianopia and gait instability. He was found to have a left occipital ring enhancing lesion that was resected. Neuropathologic examination demonstrated a Cladophialophora bantiana brain absce…
View article: Immunoglobulin G4-related disease of the cavernous sinus with orbit invasion – A case report
Immunoglobulin G4-related disease of the cavernous sinus with orbit invasion – A case report Open
Background: Immunoglobulin G4-related disease (IgG4-RD) is a rare systemic disease of unknown etiology. It is characterized by tissue infiltration caused by IgG4 plasma cells and sclerosing inflammation of various body organs. At present, …
View article: Striking MRI Changes of Focal Cortical Dysplasia Over Time
Striking MRI Changes of Focal Cortical Dysplasia Over Time Open
Our observations lead to several clinical suggestions, including closer interval follow-up imaging for nonlesional cases, the addition of postprocessing imaging methods, earlier surgical intervention, and meticulous surgical planning.
View article: Papillary Craniopharyngioma in a Young Child: The Importance of <i>BRAF</i> Mutational Testing
Papillary Craniopharyngioma in a Young Child: The Importance of <i>BRAF</i> Mutational Testing Open
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View article: Concomitant KRAS and BRAF mutations in colorectal cancer
Concomitant KRAS and BRAF mutations in colorectal cancer Open
BRAF and KRAS are two key oncogenes in the RAS/RAF/MEK/MAP-kinase signaling pathway. While previously considered mutually exclusive, concomitant mutations in both KRAS and BRAF genes have been identified in colo…
View article: Atypical Presentation of Gelsolin Amyloidosis in a Man of African Descent with a Novel Mutation in the Gelsolin Gene
Atypical Presentation of Gelsolin Amyloidosis in a Man of African Descent with a Novel Mutation in the Gelsolin Gene Open
BACKGROUND Gelsolin amyloidosis is a very rare systemic disease presenting with a pathognomonic triad of corneal lattice dystrophy, cutis laxa, and polyneuropathy. The disease is mostly restricted to a Finnish population with known mutatio…
View article: 271 Cerebellar Metastasis of Prostatic Ductal Adenocarcinoma, Beyond What We Know
271 Cerebellar Metastasis of Prostatic Ductal Adenocarcinoma, Beyond What We Know Open
Ductal adenocarcinoma is an uncommon and complex subtype of prostatic adenocarcinoma that demonstrates distinct growth patterns and molecular mutation. Herein, we report a case of metastatic ductal adenocarcinoma in cerebellum, which shows…
View article: Aggressive primary hepatic histiocytic sarcoma: case report and literature review
Aggressive primary hepatic histiocytic sarcoma: case report and literature review Open
Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination and early diagnosis of hepatoma, complications of hepatoma, and th…
View article: Post traumatic pulmonary pseudoaneurysm requiring pneumonectomy: a case report
Post traumatic pulmonary pseudoaneurysm requiring pneumonectomy: a case report Open
A 57-year-old male presented with progressive exertional dyspnea, cough, and hemoptysis. He underwent a chest computed tomography (CT) that demonstrated a 27 cm × 20 cm right chest mass that was causing a local mass effect. Pertinent histo…
View article: Serous Cystadenocarcinoma Arising in Presumed Vitelline Duct Remnant: A Case Report and Implications in the Management of Cancer of Unknown Primary
Serous Cystadenocarcinoma Arising in Presumed Vitelline Duct Remnant: A Case Report and Implications in the Management of Cancer of Unknown Primary Open
Background . Malignant neoplasms arising in Meckel’s diverticulum, a vitelline duct remnant, are rare yet well-documented. Case Presentation . A 53-year-old previously healthy female presented with an enlarging midline abdominal wall mass.…
View article: Intravascular Lymphoma With Selective Involvement of Renal Cell Carcinoma
Intravascular Lymphoma With Selective Involvement of Renal Cell Carcinoma Open