Jeremy R. Nan
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View article: Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells
Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells Open
Mutations in the protein superoxide dismutase-1 (SOD1) promote its misfolding and aggregation, ultimately causing familial forms of the debilitating neurodegenerative disease amyotrophic lateral sclerosis (ALS). Currently, over 220 (mostly…
View article: Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells
Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells Open
Mutations in the protein superoxide dismutase-1 (SOD1) promote its misfolding and aggregation, ultimately causing familial forms of the debilitating neurodegenerative disease amyotrophic lateral sclerosis (ALS). Currently, over 220 (mostly…