Jeremy Reynolds
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View article: Association Between Nutritional Status and Survival in Patients Requiring Treatment for Spinal Metastases
Association Between Nutritional Status and Survival in Patients Requiring Treatment for Spinal Metastases Open
BACKGROUND AND OBJECTIVES: The Patient-Generated Subjective Global Assessment (PG-SGA) is a standardized tool for assessing malnutrition in patients with cancer. The primary aim of this study was to assess the impact of preoperative nutrit…
View article: Anatomy of the Long Thoracic Nerve in Relation to Thoracotomy for Spinal Approaches: How to Avoid Nerve Injury?
Anatomy of the Long Thoracic Nerve in Relation to Thoracotomy for Spinal Approaches: How to Avoid Nerve Injury? Open
BACKGROUND AND OBJECTIVES: Thoracotomy and thoracoscopy are commonly used to access the thoracic spine in cases of vertebral fractures, tumors, spinal deformities, or symptomatic thoracic disc herniations. These procedures involve incision…
View article: An International Delphi Consensus on Defining the Optimal Surgical Composite Outcome in Metastatic Spine Disease
An International Delphi Consensus on Defining the Optimal Surgical Composite Outcome in Metastatic Spine Disease Open
Study Design. Delphi consensus. Objective. To define an optimal surgical composite outcome measure in patients with metastatic spine disease (OSCO-M) through international consensus among key opinion leaders. Materials and Methods. Members…
View article: New options and techniques in reconstructing the sacrum
New options and techniques in reconstructing the sacrum Open
Purpose Sacral tumours, both benign and malignant, often necessitate surgical removal (sacrectomy) to achieve optimal outcomes. However, this procedure disrupts the pelvic ring’s stability, potentially leading to pain and limited mobility.…
View article: Evaluation of Adverse Events and the Impact on Health-Related Outcomes in Patients Undergoing Surgery for Metastatic Spine Tumors: Analysis of the Metastatic Tumor Research and Outcomes Network (MTRON) Registry Dataset
Evaluation of Adverse Events and the Impact on Health-Related Outcomes in Patients Undergoing Surgery for Metastatic Spine Tumors: Analysis of the Metastatic Tumor Research and Outcomes Network (MTRON) Registry Dataset Open
Study Design This study is part of the AO Spine Metastatic Tumor Research and Outcomes Network [MTRON], an international multicenter prospective observational registry including patients with spinal metastases. Objectives This study aims t…
View article: Oxford spinal sarcoma service: excellent oncological outcomes with a centralised multidisciplinary approach to primary spinal tumour care
Oxford spinal sarcoma service: excellent oncological outcomes with a centralised multidisciplinary approach to primary spinal tumour care Open
Centralisation of primary spinal tumour care has led to excellent oncological results comparable to most large spinal tumour centres. In mobile spine primary tumours where EA margins were achieved, our local recurrence rate (2.0%) is one o…
View article: AO Spine Clinical Practice Recommendations: Current Systemic Oncological Treatments with the Largest Impact on Patients with Metastatic Spinal Disease.
AO Spine Clinical Practice Recommendations: Current Systemic Oncological Treatments with the Largest Impact on Patients with Metastatic Spinal Disease. Open
Study Design Literature review with clinical recommendation. Objective To provide the readers with a concise curation of the latest literature in recent advances in systemic oncological therapies and their implications for decision-making …
View article: AO Spine Clinical Practice Recommendations: Current Systemic Oncological Treatments with the Largest Impact on Patients with Metastatic Spinal Disease
AO Spine Clinical Practice Recommendations: Current Systemic Oncological Treatments with the Largest Impact on Patients with Metastatic Spinal Disease Open
Study Design Literature review with clinical recommendation. Objective To provide the readers with a concise curation of the latest literature in recent advances in systemic oncological therapies and their implications for decision-making …
View article: Anatomy of the diaphragmatic crura and other paraspinal structures relevant to en-bloc spondylectomy for lumbar spine tumours
Anatomy of the diaphragmatic crura and other paraspinal structures relevant to en-bloc spondylectomy for lumbar spine tumours Open
Introduction En-bloc spondylectomy in the lumbar spine is a challenging procedure mainly due to a complex prevertebral anatomy. The aim of our study is to describe the anatomy of the diaphragmatic crura and surrounding vascular and neural …
View article: The Effect of Denosumab on Pain and Radiological Improvement in Giant Cell Tumours of the Spine in the Acute Setting
The Effect of Denosumab on Pain and Radiological Improvement in Giant Cell Tumours of the Spine in the Acute Setting Open
Study Design Retrospective Cohort Study. Objectives The current recommended treatment for Giant Cell Tumour (GCT) of the spine is en bloc excision. Denosumab is a monoclonal antibody reducing osteoclast activity that shows promising result…
View article: Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm
Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm Open
Study Design Narrative Review. Objective Contextualized by a narrative review of recent literature, we propose a wound complication prevention and management algorithm for spinal oncology patients. We highlight available strategies and mot…
View article: Anatomical relationship between the greater occipital nerve and the axis: Is it possible to safely insert a percutaneous C2 screw without causing occipital neuralgia?
Anatomical relationship between the greater occipital nerve and the axis: Is it possible to safely insert a percutaneous C2 screw without causing occipital neuralgia? Open
View article: Near-Peer Student-Run Virtual STEM Summer Camp: Lessons Learned
Near-Peer Student-Run Virtual STEM Summer Camp: Lessons Learned Open
The United States Military Academy is uniquely positioned to contribute to our nation’s Science, Technology, Engineering, and Math (STEM) outreach initiatives. As one of the country’s most highly regarded undergraduate engineering schools,…
View article: Latest Developments in Targeted Biological Therapies in the Management of Chordoma and Chondrosarcoma
Latest Developments in Targeted Biological Therapies in the Management of Chordoma and Chondrosarcoma Open
Study Design Systematic review. Objectives The objective of this review paper was to summarize targeted molecular therapy options for spinal chordoma and chondrosarcoma, and to provide an update on the relevant clinical trials open for rec…
View article: Anatomy of the diaphragmatic crura and other paraspinal structures relevant to en-bloc spondylectomy for lumbar spine tumours
Anatomy of the diaphragmatic crura and other paraspinal structures relevant to en-bloc spondylectomy for lumbar spine tumours Open
Introduction: En-bloc spondylectomy in the lumbar spine is a challenging procedure mainly due to a complex prevertebral anatomy. The aim of our study is to describe the anatomy of the diaphragmatic crura and surrounding vascular and neural…
View article: Discrete Zombie Apocalypse: A Mathematical Modeling Course Project
Discrete Zombie Apocalypse: A Mathematical Modeling Course Project Open
For undergraduate mathematical modeling courses, a successful semester project can reinforce key learning objectives while enabling creativity and developing critical thinking skills. However, course directors often struggle in developing …
View article: Extradural Primary Malignant Spinal Tumors in a Population Younger than 25 Years: An Ambispective International Multicenter Study on Onco-Surgical Outcomes
Extradural Primary Malignant Spinal Tumors in a Population Younger than 25 Years: An Ambispective International Multicenter Study on Onco-Surgical Outcomes Open
Extradural malignant primary spinal tumors are rare and outcome data, especially for younger patients, is limited. In a worldwide (11 centers) study (Predictors of Mortality and Morbidity in the Surgical Management of Primary Tumors of the…
View article: Outcomes of Surgical Treatment for Extradural Benign Primary Spinal Tumors in Patients Younger than 25 Years: An Ambispective International Multicenter Study
Outcomes of Surgical Treatment for Extradural Benign Primary Spinal Tumors in Patients Younger than 25 Years: An Ambispective International Multicenter Study Open
Extradural primary spinal tumors were retrospectively analyzed from a prospective database of 1495 cases. All subjects with benign primary tumors under the age of 25 years, who were enrolled between 1990 and 2012 (Median FU was 2.4 years),…
View article: Is intraoperative cell salvage and autogenic transfusion a risk factor for postoperative metastases in spinal chordoma surgery ?
Is intraoperative cell salvage and autogenic transfusion a risk factor for postoperative metastases in spinal chordoma surgery ? Open
View article: The Use of Neo – Adjuvant Denosumab in Treatment of Giant Cell Tumours of the Spine
The Use of Neo – Adjuvant Denosumab in Treatment of Giant Cell Tumours of the Spine Open
Background The current recommended treatment for Giant Cell Tumour of the spine is en bloc excision. Denosumab is a monoclonal RANKL inhibitor that shows promising results when used as a neo – adjuvant treatment. The purpose of this study …
View article: Surgical Management of the Metastatic Spine Disease: A Review of the Literature and Proposed Algorithm
Surgical Management of the Metastatic Spine Disease: A Review of the Literature and Proposed Algorithm Open
Study Design Narrative Review. The spine remains the most common site for bony metastasis. It is estimated that up to 70% of cancer patients harbor secondary spinal disease. And up to 10% will develop a clinically significant lesion. The l…
View article: Neurological Recovery after Early Versus Delayed Surgical Decompression for Acute, Traumatic Spinal Cord Injury: A Prospective, Observational, European Multicentre (SCI-POEM) Study
Neurological Recovery after Early Versus Delayed Surgical Decompression for Acute, Traumatic Spinal Cord Injury: A Prospective, Observational, European Multicentre (SCI-POEM) Study Open
View article: The use of neo - adjuvant denosumab in treatment of giant cell tumours of the spine
The use of neo - adjuvant denosumab in treatment of giant cell tumours of the spine Open
View article: Sacral insufficiency fractures are a risk of massive bleeding during sacrectomy: patient series
Sacral insufficiency fractures are a risk of massive bleeding during sacrectomy: patient series Open
BACKGROUND Sacrectomy carries significant risk of bleeding; however, specific risk factors, apart from medical comorbidities and tumor type, for this life-threatening complication remain unclear. This study describes two cases of massive b…
View article: Calculating Utilities From the Spine Oncology Study Group Outcomes Questionnaire
Calculating Utilities From the Spine Oncology Study Group Outcomes Questionnaire Open
Study Design. General population utility valuation study. Objective. The aim of this study was to develop a technique for calculating utilities from the Spine Oncology Study Group Outcomes Questionnaire v2.0 (SOSGOQ2.0). Summary of Backgro…
View article: Feasibility of achieving planned surgical margins in primary spine tumor: a PTRON study
Feasibility of achieving planned surgical margins in primary spine tumor: a PTRON study Open
OBJECTIVE Oncological resection of primary spine tumors is associated with lower recurrence rates. However, even in the most experienced hands, the execution of a meticulously drafted plan sometimes fails. The objectives of this study were…
View article: The mental health impact of providing spine care during COVID-19
The mental health impact of providing spine care during COVID-19 Open
View article: Preventing iatrogenic facial pressure ulcers during spinal surgery: Prospective trial using a novel method and review of literature
Preventing iatrogenic facial pressure ulcers during spinal surgery: Prospective trial using a novel method and review of literature Open
To assess the outcome of a novel method of preventing facial pressure ulcers in spinal surgery and a review of literature. A prospective trial using a novel method of facial protection using paraffin tulle gras dressing to cover bony promi…
View article: Oxford Video Informed Consent Tool (OxVIC): a pilot study of informed video consent in spinal surgery and preoperative patient satisfaction
Oxford Video Informed Consent Tool (OxVIC): a pilot study of informed video consent in spinal surgery and preoperative patient satisfaction Open
Objectives The British Association of Spinal Surgeons recently called for updates in consenting practice. This study investigates the utility and acceptability of a personalised video consent tool to enhance patient satisfaction in the pre…
View article: Primary Bone Tumor of the Spine—An Evolving Field: What a General Spine Surgeon Should Know
Primary Bone Tumor of the Spine—An Evolving Field: What a General Spine Surgeon Should Know Open
Study Design: A narrative review of the literature. Objective: This article reviews the general principles of treatment and investigation for primary bone tumors of the spine. Furthermore, it explores the emerging alternatives. Methods: A …