Jeremy T Llaniguez
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View article: Quantitative and Qualitative Behavioral Measurements to Assess Pain in Axolotls (<i>Ambystoma mexicanum</i>)
Quantitative and Qualitative Behavioral Measurements to Assess Pain in Axolotls (<i>Ambystoma mexicanum</i>) Open
Effective pain relief in animals relies on the ability to discern pain and assess its severity. However, few objective measures exist to assess the presence and severity of pain in axolotls, and few resources are available regarding drugs …
View article: Noninvasive quantification of SIRT1 expression–activity and pharmacologic inhibition in a rat model of intracerebral glioma using 2-[18F]BzAHA PET/CT/MRI
Noninvasive quantification of SIRT1 expression–activity and pharmacologic inhibition in a rat model of intracerebral glioma using 2-[18F]BzAHA PET/CT/MRI Open
Background Several studies demonstrated that glioblastoma multiforme progression and recurrence is linked to epigenetic regulatory mechanisms. Sirtuin 1 (SIRT1) plays an important role in glioma progression, invasion, and treatment respons…
View article: Management of Multiple Protozoan Ectoparasites in a Research Colony of Axolotls (<i>Ambystoma mexicanum</i>)
Management of Multiple Protozoan Ectoparasites in a Research Colony of Axolotls (<i>Ambystoma mexicanum</i>) Open
Axolotls (Ambystoma mexicanum) from a research colony presented with multifocal, white chalky to gray skin lesions, a diffuse whitish to blue hue to the integument, and friable gill filaments. Skin scrapings and wet mounts revealed …
View article: Molecular imaging HDACs class IIa expression-activity and pharmacologic inhibition in intracerebral glioma models in rats using PET/CT/(MRI) with [18F]TFAHA
Molecular imaging HDACs class IIa expression-activity and pharmacologic inhibition in intracerebral glioma models in rats using PET/CT/(MRI) with [18F]TFAHA Open
HDAC class IIa enzymes (HDAC4, 5, 7, 9) are important for glioma progression, invasion, responses to TMZ and radiotherapy, and prognosis. In this study, we demonstrated the efficacy of PET/CT/(MRI) with [ 18 F]TFAHA for non-invasive and qu…