Jeremy To
YOU?
Author Swipe
View article: Retraction Note: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function
Retraction Note: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function Open
Overcoming tumor-mediated immunosuppression and enhancing cytotoxic
T-cell activity within the tumor microenvironment are two central goals of
immuno-oncology (IO) drug discovery initiatives. However, explor…
View article: RETRACTED ARTICLE: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function
RETRACTED ARTICLE: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function Open
View article: High-throughput CRISPR-mediated 3D enrichment platform for functional interrogation of chemotherapeutic resistance
High-throughput CRISPR-mediated 3D enrichment platform for functional interrogation of chemotherapeutic resistance Open
Cancer is a disease of somatic mutations. These cellular mutations compete to dominate their microenvironment and dictate the disease outcome. While a therapeutic approach to target specific driver mutations helps to manage the disease, su…
View article: Co-regulatory networks of human serum proteins link genetics to disease
Co-regulatory networks of human serum proteins link genetics to disease Open
The blood proteome in disease Understanding the function of human blood serum proteins in disease has been limited by difficulties in monitoring their production, accumulation, and distribution. Emilsson et al. investigated human serum pro…
View article: Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets
Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets Open
Recent advances in chemotherapeutics highlight the importance of molecularly-targeted perturbagens. Although these therapies typically address dysregulated cancer cell proteins, there are increasing therapeutic modalities that take into co…