Jerilynn C. Prior
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View article: SUN-109 Feasibility of Cyclic Progesterone and Spironolactone for PCOS-specific Health-Related Quality of Life—a six-month, Phase II, single arm, single center, open-label study
SUN-109 Feasibility of Cyclic Progesterone and Spironolactone for PCOS-specific Health-Related Quality of Life—a six-month, Phase II, single arm, single center, open-label study Open
Disclosure: K. Nelson: None. J. Singer: None. A. Pederson: None. D. Kalidasan: None. J. Prior: None. Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that significantly decreases health-related quality of life (HRQoL). C…
View article: SAT-128 Prospective 1-year Menstrual CycleBreast Tenderness and Swelling Experiences—data from healthy regularly cycling women initially proven normally ovulatory on two consecutive cycles
SAT-128 Prospective 1-year Menstrual CycleBreast Tenderness and Swelling Experiences—data from healthy regularly cycling women initially proven normally ovulatory on two consecutive cycles Open
Disclosure: M. Wood: None. J.C. Prior: None. S. Shirin: None. A. Goshtasebi: None. Breast tenderness and swelling are associated with premenstrual symptoms but have not been well described in healthy, normally cycling women with known ovul…
View article: MON-154 Breast areolar diameter in healthy menstruating women—a single cycle cross-sectional study of associations with body size and ovulatory characteristics
MON-154 Breast areolar diameter in healthy menstruating women—a single cycle cross-sectional study of associations with body size and ovulatory characteristics Open
Disclosure: A.V. Baaske: None. S. Shirin: None. C. Bos: None. D. Kalidasan: None. J.C. Prior: None. Background: Tanner Breast Stage 3 (TB3, at menarche) and Tanner 5 (TB5, once ovulatory cycles established), despite being similar with an “…
View article: Feeling of self-worth in healthy premenopausal women—relationships with menstrual cycles and ovulation over 1-year in the prospective ovulation cohort
Feeling of self-worth in healthy premenopausal women—relationships with menstrual cycles and ovulation over 1-year in the prospective ovulation cohort Open
Self-Worth is an over-arching evaluation of a person’s sense of individual value. Self-worth, however, is an underappreciated concept. It has rarely been reported related to physiological data; we found no studies related to the menstrual …
View article: Ovulatory and anovulatory cycle phase influences on QT interval dynamics during the menstrual cycle
Ovulatory and anovulatory cycle phase influences on QT interval dynamics during the menstrual cycle Open
Background Ovarian hormones affect cardiovascular health yet few sufficient-sized studies with reliable ovulatory documentation have assessed the QTc-hormonal relationship. This study investigated QTc changes across ovulatory and anovulato…
View article: Breast tenderness and swelling experiences related to menstrual cycles and ovulation in healthy premenopausal women: Secondary analysis of the 1-year “Prospective Ovulation Cohort”
Breast tenderness and swelling experiences related to menstrual cycles and ovulation in healthy premenopausal women: Secondary analysis of the 1-year “Prospective Ovulation Cohort” Open
Breast tenderness and swelling are associated with premenstrual symptoms but are not well described in healthy women. In this 1-year prospective observational study, we examined daily breast tenderness and swelling to determine whether dif…
View article: Energy Intake and Appetite in Laboratory and Free-Living Conditions are Consistent Across Menstrual Cycle Phases
Energy Intake and Appetite in Laboratory and Free-Living Conditions are Consistent Across Menstrual Cycle Phases Open
View article: Retraction Note: A one-year observational cohort study of menstrual cramps and ovulation in healthy, normally ovulating women
Retraction Note: A one-year observational cohort study of menstrual cramps and ovulation in healthy, normally ovulating women Open
View article: Prospective 1-year assessment of within-woman variability of follicular and luteal phase lengths in healthy women prescreened to have normal menstrual cycle and luteal phase lengths
Prospective 1-year assessment of within-woman variability of follicular and luteal phase lengths in healthy women prescreened to have normal menstrual cycle and luteal phase lengths Open
STUDY QUESTION What is the relative length variance of the luteal phase compared to the follicular phase within healthy, non-smoking, normal-weight, proven normally ovulatory, premenopausal women with normal-length menstrual cycles? SUMMAR…
View article: Associations of Early Prolonged Secondary Amenorrhea in Women With and Without HIV
Associations of Early Prolonged Secondary Amenorrhea in Women With and Without HIV Open
Background The menstrual cycle is a critical indicator of women's health. Early prolonged secondary amenorrhea increases risks for morbidity and mortality. Menstrual cycle research in women with HIV is inconsistent and often lacks an adequ…
View article: Author Correction: Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial
Author Correction: Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial Open
View article: Menstrual Cramps in Anovulatory versus Normally Ovulatory Cycles — SARS-COV-2 Pandemic Daily Data Plus a Meta-Analysis of Cramps and Anovulation
Menstrual Cramps in Anovulatory versus Normally Ovulatory Cycles — SARS-COV-2 Pandemic Daily Data Plus a Meta-Analysis of Cramps and Anovulation Open
This is the first documentation of more intense and frequent cramps in anovulatory cycles. However, meta-analysis showing the presence of symptomatic cramps in both ovulatory and anovulatory cycles documented they were twice as prevalent i…
View article: Sedentary behavior does not predict low BMD nor fracture—population-based Canadian Multicentre Osteoporosis Study
Sedentary behavior does not predict low BMD nor fracture—population-based Canadian Multicentre Osteoporosis Study Open
Sedentary behavior (SB) or sitting is associated with multiple unfavorable health outcomes. Bone tissue responds to imposed gravitational and muscular strain with there being some evidence suggesting a causal link between SB and poor bone …
View article: Experiences of women living with Polycystic Ovary Syndrome: A pilot case-control, single-cycle, daily Menstrual Cycle Diary study during the SARS-CoV-2 pandemic
Experiences of women living with Polycystic Ovary Syndrome: A pilot case-control, single-cycle, daily Menstrual Cycle Diary study during the SARS-CoV-2 pandemic Open
Polycystic Ovary Syndrome (PCOS) affects many people and is often distressing. Much medical literature about diagnosis and treatment exists, but little is known about PCOS menstrual cycle-related experiences except that cycles tend to be f…
View article: Don’t ignore perimenopause
Don’t ignore perimenopause Open
We agree with Lega and colleagues[1][1] that menopausal hormone therapy (MHT) has been shown in randomized controlled trials (RCTs) to be effective and safe for treating problematic vasomotor symptoms related to menopause. We also agree th…
View article: Long‐Term Change in Bone Mineral Density in Women Living With <scp>HIV</scp>: A 10‐Year Prospective Controlled Cohort Study
Long‐Term Change in Bone Mineral Density in Women Living With <span>HIV</span>: A 10‐Year Prospective Controlled Cohort Study Open
Women living with HIV (WLWH) may be at higher risk for osteoporosis and fragility fractures. However, limited prospective data describe long‐term trajectories of bone mineral density (BMD) in WLWH versus women without HIV. Thus, in this pr…
View article: Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial
Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial Open
This study tested progesterone for perimenopausal hot flush ± night sweat (vasomotor symptom, VMS) treatment. It was a double-blind, randomized trial of 300 mg oral micronized progesterone@bedtime versus placebo for 3-months (m) after a 1-…
View article: Age at Natural Menopause in Women Living with HIV: A Cross-Sectional Study Comparing Self-Reported and Biochemical Data
Age at Natural Menopause in Women Living with HIV: A Cross-Sectional Study Comparing Self-Reported and Biochemical Data Open
Early menopause ( 0.05). Overall, HIV status per se was not statistically associated with an earlier age at menopause, emphasizing the importance of comparing socio-demographically similar women in reproductive health and HIV research.
View article: Lower anti-Müllerian hormone levels are associated with HIV in reproductive age women and shorter leukocyte telomere length among late reproductive age women
Lower anti-Müllerian hormone levels are associated with HIV in reproductive age women and shorter leukocyte telomere length among late reproductive age women Open
Objectives: We sought to better understand factors associated with ovarian aging in women with HIV (WWH). Design: HIV has been associated with diminished fertility, younger age at menopause, and shorter leukocyte telomere length (LTL), a m…
View article: 26 Combined hormonal contraceptive use is not protective against musculoskeletal conditions or injuries: A systematic review with data from 5-million women
26 Combined hormonal contraceptive use is not protective against musculoskeletal conditions or injuries: A systematic review with data from 5-million women Open
Introduction Half of young women start combined hormonal contraceptive (CHC) use for non-contraceptive reasons including 'controlling' their menstrual cycle to prevent injuries. These decisions should be evidence-based. This study assessed…
View article: OR15-6 Epidemic of Subclinical Ovulatory Disturbances During SARS-COV2 Pandemic—an Experiment of Nature
OR15-6 Epidemic of Subclinical Ovulatory Disturbances During SARS-COV2 Pandemic—an Experiment of Nature Open
During the SARS-COV2 pandemic (COVID-19) many studies have examined changes in women's stress, depression/anxiety, reproduction, plus post-vaccination cycle/flow changes1. Although there are retrospective basal temperature data2, we lack m…
View article: Letter to the Editor From Nelson et al: “Understanding the Link Between Obesity and Severe COVID-19 Outcomes: Causal Mediation by Systemic Inflammatory Response”
Letter to the Editor From Nelson et al: “Understanding the Link Between Obesity and Severe COVID-19 Outcomes: Causal Mediation by Systemic Inflammatory Response” Open
View article: Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea
Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea Open
OPINION article Front. Endocrinol., 19 October 2022Sec. Reproduction Volume 13 - 2022 | https://doi.org/10.3389/fendo.2022.893889
View article: RETRACTED ARTICLE: A one-year observational cohort study of menstrual cramps and ovulation in healthy, normally ovulating women
RETRACTED ARTICLE: A one-year observational cohort study of menstrual cramps and ovulation in healthy, normally ovulating women Open
View article: Assessing the role of adolescent hormonal contraceptive use on risk for depression: a 3-year longitudinal study protocol
Assessing the role of adolescent hormonal contraceptive use on risk for depression: a 3-year longitudinal study protocol Open
Background The incidence of depression in human females rises steadily throughout adolescence, a critical period of pubertal maturation marked by increasing levels of gonadal hormones including estrogens and progesterone. These gonadal hor…
View article: Prospective analyses of sex/gender-related publication decisions in general medical journals: editorial rejection of population-based women’s reproductive physiology
Prospective analyses of sex/gender-related publication decisions in general medical journals: editorial rejection of population-based women’s reproductive physiology Open
Objective To assess whether editorial desk rejection at general medical journals (without peer review) of two clinical research manuscripts may relate to author gender or women’s physiology topics. Given evidence for bias related to women …
View article: Factors associated with contraceptive use among women living with HIV in Canada: a controlled, cross-sectional study
Factors associated with contraceptive use among women living with HIV in Canada: a controlled, cross-sectional study Open
Background Multiple contraindications to combined hormonal contraceptives (CHC) use exist. The impact of these factors on contraceptive choice, particularly among women living with HIV (WLWH), is not well understood. We measured and compar…
View article: “The pill” suppresses adolescent bone growth, no matter the estrogen dose
“The pill” suppresses adolescent bone growth, no matter the estrogen dose Open
We appreciated the recent CMAJ article about adolescent contraception.[1][1] We especially support the statement that long-acting reversible contraceptive agents, such as implants and intrauterine devices, are ideally first-line methods fo…
View article: Where’s the break? Critique of radiographic vertebral fracture diagnostic methods
Where’s the break? Critique of radiographic vertebral fracture diagnostic methods Open
View article: Cyclic Progesterone Therapy in Androgenic Polycystic Ovary Syndrome (PCOS)—A 6-Month Pilot Study of a Single Woman’s Experience Changes
Cyclic Progesterone Therapy in Androgenic Polycystic Ovary Syndrome (PCOS)—A 6-Month Pilot Study of a Single Woman’s Experience Changes Open
Background and Objectives: Women with androgenic Polycystic Ovary Syndrome (PCOS) have increased endometrial cancer risk that cyclic progesterone will prevent; it may also reverse PCOS’s neuroendocrine origins. This pilot study’s purpose w…