Jernej Gašperšič
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View article: Biotechnology and Bioengineering: Volume 120, Number 2, February 2023
Biotechnology and Bioengineering: Volume 120, Number 2, February 2023 Open
View article: Viral and Host Genetic and Epigenetic Biomarkers Related to SARS-CoV-2 Cell Entry, Infection Rate, and Disease Severity
Viral and Host Genetic and Epigenetic Biomarkers Related to SARS-CoV-2 Cell Entry, Infection Rate, and Disease Severity Open
The rapid spread of COVID-19 outbreak lead to a global pandemic declared in March 2020. The common features of corona virus family helped to resolve structural characteristics and entry mechanism of SARS-CoV-2. However, rapid mutagenesis l…
View article: Erythrocytosis: genes and pathways involved in disease development.
Erythrocytosis: genes and pathways involved in disease development. Open
Erythrocytosis is a blood disorder characterised by an increased red blood cell mass. The most common causes of erythrocytosis are acquired and caused by diseases and conditions that are accompanied by hypoxaemia or overproduction of eryth…
View article: Genetic analysis of 39 erythrocytosis and hereditary hemochromatosis‐associated genes in the Slovenian family with idiopathic erythrocytosis
Genetic analysis of 39 erythrocytosis and hereditary hemochromatosis‐associated genes in the Slovenian family with idiopathic erythrocytosis Open
Background Erythrocytosis is a condition with an excessive number of erythrocytes, accompanied by an elevated haemoglobin and/or haematocrit value. Congenital erythrocytosis has a diverse genetic background with several genes involved in e…
View article: Potential of modern circulating cell-free DNA diagnostic tools for detection of specific tumour cells in clinical practice
Potential of modern circulating cell-free DNA diagnostic tools for detection of specific tumour cells in clinical practice Open
Personalized medicine is a developing field of medicine that has gained in importance in recent decades. New diagnostic tests based on the analysis of circulating cell-free DNA (cfDNA) were developed as a tool of diagnosing different cance…
View article: Metabolic Network Modelling of Chinese Hamster Ovary (CHO) Culture Bioreactors Operated as Microbial Cell Factories
Metabolic Network Modelling of Chinese Hamster Ovary (CHO) Culture Bioreactors Operated as Microbial Cell Factories Open
Chinese hamster ovary (CHO) epithelial cells are one of the most used therapeutic medical lines for the production of different biopharmaceutical drugs. They have a high consumption rate with a fast duplication cycle that makes them an ide…
View article: Depletion of human serum albumin in embryo culture media for in vitro fertilization using monolithic columns with immobilized antibodies
Depletion of human serum albumin in embryo culture media for in vitro fertilization using monolithic columns with immobilized antibodies Open
Affinity depletion of abundant proteins such as HSA is an important stage in routine sample preparation prior to MS/MS analysis of biological samples with high range of concentrations. Due to the charge competition effects in electrospray …
View article: Methacrylate monolith chromatography as a tool for waterborne virus removal
Methacrylate monolith chromatography as a tool for waterborne virus removal Open
Enteric viruses are commonly present in environmental waters and represent the major cause of waterborne infections and outbreaks. Since traditional wastewater treatments fail to remove enteric viruses in the water purification process, th…