Jeroen A. van Waarde
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View article: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects
Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects Open
View article: Speeding Up Response Time for Antidepressive Treatment
Speeding Up Response Time for Antidepressive Treatment Open
View article: Postictal resting-state connectivity changes after electroconvulsive therapy-induced seizures
Postictal resting-state connectivity changes after electroconvulsive therapy-induced seizures Open
Electroconvulsive therapy (ECT) leads to temporary changes of brain function. It is unclear what changes take place shortly after the induced seizures. Here, we present the first human study on resting-state network (RSN) changes in the im…
View article: Electroconvulsive therapy induces rapid microstructural and macrostructural changes, but microstructural changes are longer-lasting
Electroconvulsive therapy induces rapid microstructural and macrostructural changes, but microstructural changes are longer-lasting Open
Background Electroconvulsive therapy (ECT) is an effective treatment for major depressive episodes, though its mechanisms remain unclear. Its use is limited due to stigma and possible cognitive side-effects. Repeated magnetic resonance ima…
View article: The relationship between electric field strength induced by electroconvulsive therapy and cognitive and antidepressant outcomes
The relationship between electric field strength induced by electroconvulsive therapy and cognitive and antidepressant outcomes Open
View article: A prediction model for electroconvulsive therapy effectiveness in patients with major depressive disorder from the Dutch ECT Consortium (DEC)
A prediction model for electroconvulsive therapy effectiveness in patients with major depressive disorder from the Dutch ECT Consortium (DEC) Open
View article: Exploring postictal recovery with acetaminophen or nimodipine: A randomized‐controlled crossover trial
Exploring postictal recovery with acetaminophen or nimodipine: A randomized‐controlled crossover trial Open
Objective The postictal state is underrecognized in epilepsy. Animal models show improvement of postictal symptoms and cerebral perfusion with acetaminophen or nimodipine. We studied the effects of acetaminophen or nimodipine on postictal …
View article: Restoration of postictal cortical activity after electroconvulsive therapy relates to recovery of orientation in person, place, and time
Restoration of postictal cortical activity after electroconvulsive therapy relates to recovery of orientation in person, place, and time Open
Background Most patients show temporary impairments in clinical orientation after electroconvulsive therapy (ECT)-induced seizures. It is unclear how postictal reorientation relates to electroencephalography (EEG) restoration. This relatio…
View article: Longitudinal resting-state network connectivity changes in electroconvulsive therapy patients compared to healthy controls
Longitudinal resting-state network connectivity changes in electroconvulsive therapy patients compared to healthy controls Open
DMN within-network connectivity normalized after ECT. Within-network increase of the LFPN in ECT patients was correlated with higher treatment effectiveness. In contrast to earlier studies, we found no whole-brain voxel-wise changes, which…
View article: Correction: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Correction: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression Open
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View article: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression Open
View article: Changes in postictal cerebral perfusion are related to the duration of electroconvulsive therapy‐induced seizures
Changes in postictal cerebral perfusion are related to the duration of electroconvulsive therapy‐induced seizures Open
Objective Postictal symptoms may result from cerebral hypoperfusion, which is possibly a consequence of seizure‐induced vasoconstriction. Longer seizures have previously been shown to cause more severe postictal hypoperfusion in rats and e…
View article: Alpha peak frequency-based Brainmarker-I as a method to stratify to pharmacotherapy and brain stimulation treatments in depression
Alpha peak frequency-based Brainmarker-I as a method to stratify to pharmacotherapy and brain stimulation treatments in depression Open
Biomarkers predicting treatment outcome in major depressive disorder could enhance clinical improvement. Here this observational and prospective accuracy study investigates whether an age- and sex-normalized electroencephalography biomarke…
View article: A Multicenter Retrospective Chart Review on the Effectiveness and Tolerability of Electroconvulsive Therapy in Adolescents and Young Adults With Major Depressive Disorder or Bipolar Depression
A Multicenter Retrospective Chart Review on the Effectiveness and Tolerability of Electroconvulsive Therapy in Adolescents and Young Adults With Major Depressive Disorder or Bipolar Depression Open
Background Major depressive disorder and bipolar depression in adolescents and young adults are prevalent and major contributors to the global burden of disease, whereas effective interventions are limited. Available evidence is insufficie…
View article: Cortical excitation/inhibition ratios in patients with major depression treated with electroconvulsive therapy: an EEG analysis
Cortical excitation/inhibition ratios in patients with major depression treated with electroconvulsive therapy: an EEG analysis Open
Electroconvulsive therapy (ECT) is an effective treatment for major depression, but its working mechanisms are poorly understood. Modulation of excitation/inhibition (E/I) ratios may be a driving factor. Here, we estimate cortical E/I rati…
View article: Effective resting-state connectivity in severe unipolar depression before and after electroconvulsive therapy
Effective resting-state connectivity in severe unipolar depression before and after electroconvulsive therapy Open
View article: The impact of treatment resistance on outcome and course of electroconvulsive therapy in major depressive disorder
The impact of treatment resistance on outcome and course of electroconvulsive therapy in major depressive disorder Open
Introduction Major depressive disorder (MDD) is a common psychiatric disorder. Despite several treatment options, a subgroup of patients will not respond to the commonly used antidepressant treatments and thus express treatment resistance …
View article: Polyunsaturated fatty acids changes during electroconvulsive therapy in major depressive disorder
Polyunsaturated fatty acids changes during electroconvulsive therapy in major depressive disorder Open
View article: Medication preventing postictal hypoperfusion and cognitive side-effects in electroconvulsive therapy: A retrospective cohort study
Medication preventing postictal hypoperfusion and cognitive side-effects in electroconvulsive therapy: A retrospective cohort study Open
Background Electroconvulsive therapy (ECT) is associated with postictal confusion and cognitive side-effects. In rats, acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs) and calcium antagonists decreased postictal cerebral hypop…
View article: Seizure duration predicts postictal electroencephalographic recovery after electroconvulsive therapy-induced seizures
Seizure duration predicts postictal electroencephalographic recovery after electroconvulsive therapy-induced seizures Open
Quantitative EEG allows objective assessment of the postictal state.
View article: Sex-specifics of ECT outcome
Sex-specifics of ECT outcome Open
View article: Decreased regional postictal perfusion after electroconvulsive therapy-induced seizures measured with arterial spin labelling
Decreased regional postictal perfusion after electroconvulsive therapy-induced seizures measured with arterial spin labelling Open
View article: Association between the preceding number of electroconvulsive therapy-induced seizures and postictal EEG recovery
Association between the preceding number of electroconvulsive therapy-induced seizures and postictal EEG recovery Open
View article: Rostral Anterior Cingulate Cortex Oscillatory Power Indexes Treatment-Resistance to Multiple Therapies in Major Depressive Disorder
Rostral Anterior Cingulate Cortex Oscillatory Power Indexes Treatment-Resistance to Multiple Therapies in Major Depressive Disorder Open
Introduction: High rostral anterior cingulate cortex (rACC) activity is proposed as a nonspecific prognostic marker for treatment response in major depressive disorder, independent of treatment modality. However, other studies report a neg…
View article: Multimodal multi-center analysis of electroconvulsive therapy effects in depression: Brainwide gray matter increase without functional changes
Multimodal multi-center analysis of electroconvulsive therapy effects in depression: Brainwide gray matter increase without functional changes Open
Background: Electroconvulsive therapy (ECT) is an effective treatment for severe depression and induces gray matter (GM) increases in the brain. Small-scale studies suggest that ECT also leads to changes in brain functioning, but findings …
View article: Negative cognitive schema modification as mediator of symptom improvement after electroconvulsive therapy in major depressive disorder
Negative cognitive schema modification as mediator of symptom improvement after electroconvulsive therapy in major depressive disorder Open
View article: Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE)
Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE) Open
View article: Pharmacological interventions to diminish cognitive side effects of electroconvulsive therapy: A systematic review and meta‐analysis
Pharmacological interventions to diminish cognitive side effects of electroconvulsive therapy: A systematic review and meta‐analysis Open
Objective The authors conducted a systematic review and meta‐analysis of pharmacological interventions to diminish cognitive side effects of ECT. Methods Electronic databases of Pubmed, PsycInfo, Embase and Scopus were searched from incept…
View article: Case Report: “Niemann-Pick Disease Type C in a Catatonic Patient Treated With Electroconvulsive Therapy”
Case Report: “Niemann-Pick Disease Type C in a Catatonic Patient Treated With Electroconvulsive Therapy” Open
We describe a case of an adolescent male with Niemann-Pick Type C (NP-C), a neurodegenerative lysosomal lipid storage disorder, who presented with recurrent catatonia which required repeated treatment with electroconvulsive therapy (ECT). …
View article: Seizures induced in electroconvulsive therapy as a human epilepsy model: A comparative case study
Seizures induced in electroconvulsive therapy as a human epilepsy model: A comparative case study Open
Objective Standardized investigation of epileptic seizures and the postictal state may contribute to a better understanding of ictal and postictal phenomena. This comparative case study aims to assess whether electrically induced seizures …