Jeroen Wagemans
YOU?
Author Swipe
View article: A link to the past: classical phage ISP infects the recently described Staphylococcus borealis species
A link to the past: classical phage ISP infects the recently described Staphylococcus borealis species Open
Background Staphylococcal infections, caused by a large variety of species within the Staphylococcus genus, are a threat to human health. Although antibiotics are the current choice of treatment for these infections, bacteriophage (phage) …
View article: Inflammation, toxicity, and apoptosis reducing potential of bacteriophage Ariobarzanes on intestinal cells infected with Salmonella Typhimurium
Inflammation, toxicity, and apoptosis reducing potential of bacteriophage Ariobarzanes on intestinal cells infected with Salmonella Typhimurium Open
View article: Alhagi maurorum extract in combination with lytic phage cocktails: a promising therapeutic approach against biofilms of multi-drug resistant P. mirabilis
Alhagi maurorum extract in combination with lytic phage cocktails: a promising therapeutic approach against biofilms of multi-drug resistant P. mirabilis Open
Antimicrobial resistance (AMR) poses a significant global threat to public health systems, rendering antibiotics ineffective in treating infectious diseases. Combined use of bio compounds, including bacteriophages and plant extracts, is an…
View article: Prolonged Disease Remission of the Chronic Immunological Skin Disorder Hidradenitis Suppurativa with Bacteriophage Therapy
Prolonged Disease Remission of the Chronic Immunological Skin Disorder Hidradenitis Suppurativa with Bacteriophage Therapy Open
Hidradenitis suppurativa (HS) is a chronic skin disease in which the acute development of noduli, abscesses and in a later stage fistula’s remains difficult to control, despite a wide range of recommended treatment options including immuno…
View article: Isolation, characterization and genome analysis of the orphan phage Kintu infecting Xanthomonas vasicola pv. musacearum
Isolation, characterization and genome analysis of the orphan phage Kintu infecting Xanthomonas vasicola pv. musacearum Open
View article: Characterization of four <i>Acidovorax</i> phages and their potential in phage biocontrol for lamb’s lettuce seed decontamination
Characterization of four <i>Acidovorax</i> phages and their potential in phage biocontrol for lamb’s lettuce seed decontamination Open
Bacterial black spot, caused by Acidovorax valerianellae , is responsible for significant yield losses in lamb’s lettuce ( Valerianella locusta ) in many producing countries, especially Europe. Currently, no resistant varieties of V. locus…
View article: Isolation and Antibiofilm Activity of Bacteriophages against Cutibacterium acnes from Patients with Periprosthetic Joint Infection
Isolation and Antibiofilm Activity of Bacteriophages against Cutibacterium acnes from Patients with Periprosthetic Joint Infection Open
Background: Infections following shoulder surgery, particularly periprosthetic joint infection (PJI), are challenging to treat. Cutibacterium acnes is the causative pathogen in 39% to 76% of these cases. This study explores the efficacy of…
View article: Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs
Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs Open
View article: Optimization of bacteriophage therapy for difficult-to-treat musculoskeletal infections: a bench-to-bedside perspective
Optimization of bacteriophage therapy for difficult-to-treat musculoskeletal infections: a bench-to-bedside perspective Open
Given the increasing threat of antimicrobial resistance, scientists are urgently seeking adjunct antimicrobial strategies, such as phage therapy (PT). However, despite promising results for the treatment of musculoskeletal infections in ou…
View article: AN OUTBREAK OF EXTENSIVELY DRUG-RESISTANT <i>ACINETOBACTER BAUMANNII</i> IN A BELGIAN TERTIARY BURN WOUND CENTER.
AN OUTBREAK OF EXTENSIVELY DRUG-RESISTANT <i>ACINETOBACTER BAUMANNII</i> IN A BELGIAN TERTIARY BURN WOUND CENTER. Open
The burn intensive care unit (ICU) of the Queen Astrid Military Hospital experienced an outbreak with an extensively drug-resistant Acinetobacter baumannii (XDR-Ab) strain, which began when all burn wound patients from all over Belg…
View article: Evaluation of antibiofilm agents for treatment of cystic fibrosis‐related chronic rhinosinusitis
Evaluation of antibiofilm agents for treatment of cystic fibrosis‐related chronic rhinosinusitis Open
Key points Treatment of cystic fibrosis‐related chronic rhinosinusitis should target sinonasal biofilms. NaHCO 3 salts with/without xylitol have limited antibiofilm properties, whereas rhDNAse has not. Phage effectivity varies and depends …
View article: Combination of bacteriophages and vancomycin in a co-delivery hydrogel for localized treatment of fracture-related infections
Combination of bacteriophages and vancomycin in a co-delivery hydrogel for localized treatment of fracture-related infections Open
Fracture-related infections (FRIs), particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA), are challenging to treat. This study designed and evaluated a hydrogel loaded with a cocktail of bacteriophages and vancom…
View article: Targeted enhancement of bacteriophage activity against antibiotic-resistant Staphylococcus aureus biofilms through an evolutionary assay
Targeted enhancement of bacteriophage activity against antibiotic-resistant Staphylococcus aureus biofilms through an evolutionary assay Open
Staphylococcus aureus ´ biofilm-forming ability and rapid resistance development pose a significant challenge to successful treatment, particularly in postoperative complications, emphasizing the need for enhanced therapeutic strategies. B…
View article: Phage-Mediated Digestive Decolonization in a Gut-On-A-Chip Model: A Tale of Gut-Specific Bacterial Prosperity
Phage-Mediated Digestive Decolonization in a Gut-On-A-Chip Model: A Tale of Gut-Specific Bacterial Prosperity Open
Infections due to antimicrobial-resistant bacteria have become a major threat to global health. Some patients may carry resistant bacteria in their gut microbiota. Specific risk factors may trigger the conversion of these carriages into in…
View article: Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study Open
View article: Use of the Naturally Occurring Bacteriophage Grouping Model for the Design of Potent Therapeutic Cocktails
Use of the Naturally Occurring Bacteriophage Grouping Model for the Design of Potent Therapeutic Cocktails Open
The specificity of phages and their ability to evolve and overcome bacterial resistance make them potentially useful as adjuncts in the treatment of antibiotic-resistant bacterial infections. The goal of this study was to mimic a natural g…
View article: Isolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin
Isolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin Open
View article: Meeting Report of the Second Symposium of the Belgian Society for Viruses of Microbes and Launch of the Phage Valley
Meeting Report of the Second Symposium of the Belgian Society for Viruses of Microbes and Launch of the Phage Valley Open
The second symposium of the Belgian Society for Viruses of Microbes (BSVoM) took place on 8 September 2023 at the University of Liège with 141 participants from 10 countries. The meeting program covered three thematic sessions opened by in…
View article: Controlling of foodborne pathogen biofilms on stainless steel by bacteriophages: A systematic review and meta-analysis
Controlling of foodborne pathogen biofilms on stainless steel by bacteriophages: A systematic review and meta-analysis Open
This study investigates the potential of using bacteriophages to control foodborne pathogen biofilms on stainless steel surfaces in the food industry. Biofilm-forming bacteria can attach to stainless steel surfaces, rendering them difficul…
View article: Exploiting phage-antibiotic synergies to disrupt <i>Pseudomonas aeruginosa</i> PAO1 biofilms in the context of orthopedic infections
Exploiting phage-antibiotic synergies to disrupt <i>Pseudomonas aeruginosa</i> PAO1 biofilms in the context of orthopedic infections Open
In recent years, bacteriophages (or phages) have reentered the spotlight as alternative or adjuvant therapeutic agents to antibiotics. Their efficacy in more recalcitrant forms of infections like biofilms, frequently encountered in the ort…
View article: Understanding the bacterial imbalance in Hidradenitis Suppurativa patients: Insights into microbial community shifts and colonization by opportunistic pathogens
Understanding the bacterial imbalance in Hidradenitis Suppurativa patients: Insights into microbial community shifts and colonization by opportunistic pathogens Open
Patients suffering from hidradenitis suppurativa (HS) develop painful skin lesions, significantly decreasing their quality of life. This chronic disease is triggered by plugged hair follicles resulting in an aberrant immune response, skin …
View article: ECOPHAGE: Combating Antimicrobial Resistance Using Bacteriophages for Eco-Sustainable Agriculture and Food Systems
ECOPHAGE: Combating Antimicrobial Resistance Using Bacteriophages for Eco-Sustainable Agriculture and Food Systems Open
The focus of this meeting was to discuss the suitability of using bacteriophages as alternative antimicrobials in the agrifood sector. Following a One Health approach, the workshop explored the possibilities of implementing phage applicati…
View article: Hidradenitis Suppurativa Patients Exhibit a Distinctive and Highly Individualized Skin Virome
Hidradenitis Suppurativa Patients Exhibit a Distinctive and Highly Individualized Skin Virome Open
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by recurring painful skin lesions. Despite ongoing research, the exact cause underlying the initiation and progression of disease remains unknown. While prior re…
View article: Isolation and molecular characterization of the Salmonella Typhimurium orphan phage Arash
Isolation and molecular characterization of the Salmonella Typhimurium orphan phage Arash Open
View article: Assessing the environmental biosafety of phage-based biocontrol applications
Assessing the environmental biosafety of phage-based biocontrol applications Open
View article: Stability of magistral phage preparations before therapeutic application in patients with chronic rhinosinusitis, sepsis, pulmonary, and musculoskeletal infections
Stability of magistral phage preparations before therapeutic application in patients with chronic rhinosinusitis, sepsis, pulmonary, and musculoskeletal infections Open
Bacteriophages have (re)gained popularity as an adjunct antibacterial therapy. On top of the self-amplifying character of phages, their titer can be influenced by several factors which could lead to reduced titers after preparation and sto…
View article: Retrospective, observational analysis of the first one hundred consecutive cases of personalized bacteriophage therapy of difficult-to-treat infections facilitated by a Belgian consortium
Retrospective, observational analysis of the first one hundred consecutive cases of personalized bacteriophage therapy of difficult-to-treat infections facilitated by a Belgian consortium Open
In contrast to the many reports of successful cases of personalized bacteriophage therapy, randomized controlled trials of non-personalized bacteriophage products did not bring the expected results. Here, we present the outcomes of a retro…
View article: Isolation and Characterization of the Acadevirus Members BigMira and MidiMira Infecting a Highly Pathogenic Proteus mirabilis Strain
Isolation and Characterization of the Acadevirus Members BigMira and MidiMira Infecting a Highly Pathogenic Proteus mirabilis Strain Open
Proteus mirabilis is an opportunistic pathogen and is responsible for more than 40% of all cases of catheter-associated urinary tract infections (CAUTIs). Healthcare-associated infections have been aggravated by the constant emergence of a…
View article: Targeting MDR Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs
Targeting MDR Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs Open
Spread of multidrug-resistant Pseudomonas aeruginosa strains threatens to render currently available antibiotics obsolete, with limited prospects for the development of new antibiotics. Lytic bacteriophages (phages), the natural predators …
View article: Phage therapy for hidradenitis suppurativa: a unique challenge and possible opportunity for personalized treatment of a complex, inflammatory disease
Phage therapy for hidradenitis suppurativa: a unique challenge and possible opportunity for personalized treatment of a complex, inflammatory disease Open
Phage therapy is an emerging antimicrobial treatment for critical multidrug-resistant pathogens. In this review, the specific potential and challenges of phage therapy for patients with hidradenitis suppurativa (HS) are discussed. This rep…