Jerome Genth
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View article: Cover Image, Volume 45, Issue 7
Cover Image, Volume 45, Issue 7 Open
The cover image is based on the article Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis by Felix Sommer et al…
View article: Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis
Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis Open
View article: Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice
Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice Open
Background A metabolic switch favoring glycolysis over aerobic oxidative phosphorylation, namely the “Warburg effect”, represents a hallmark of cancer cells. Hexokinases (HK) catalyze the first step of glycolysis, thereby regulating its ra…
View article: Identification of proteoforms of short open reading frame-encoded peptides in <i>Blautia producta</i> under different cultivation conditions
Identification of proteoforms of short open reading frame-encoded peptides in <i>Blautia producta</i> under different cultivation conditions Open
Short open reading frames (sORF) have the potential to encode small proteins, sORF-encoded peptides (SEP), which are less than or equal to 100 amino acids in length. These SEP have been associated with various physiological processes and a…
View article: The intracellular proteome of the gut bacterium <i>Bacteroides thetaiotaomicron</i> is widely unaffected by a switch from glucose to sucrose as main carbohydrate source
The intracellular proteome of the gut bacterium <i>Bacteroides thetaiotaomicron</i> is widely unaffected by a switch from glucose to sucrose as main carbohydrate source Open
Bacteroides thetaiotaomicron is a gram negative bacterium within the human gut microbiome that metabolizes a wide range of dietary and mucosal polysaccharides. Here, we analyze the proteome response of B. thetaiotaomicron cultivated on two…