Jérôme Labbé
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View article: 147P Pre-clinical evaluation and safety profile of the highly selective anti-VISTA antibody K01401-020
147P Pre-clinical evaluation and safety profile of the highly selective anti-VISTA antibody K01401-020 Open
V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an immune checkpoint regulator that is highly expressed in myeloid cells in the tumor microenvironment (TME). VISTA has been shown to maintain immunosuppressive conditions …
View article: Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet
Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet Open
View article: Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice
Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice Open
View article: Polysaccharide Chain Length of Lipopolysaccharides From Salmonella Minnesota Is a Determinant of Aggregate Stability, Plasma Residence Time and Proinflammatory Propensity in vivo
Polysaccharide Chain Length of Lipopolysaccharides From Salmonella Minnesota Is a Determinant of Aggregate Stability, Plasma Residence Time and Proinflammatory Propensity in vivo Open
Lipopolysaccharides (LPS) originate from the outer membrane of Gram-negative bacteria and trigger an inflammatory response via the innate immune system. LPS consist of a lipid A moiety directly responsible for the stimulation of the…
View article: Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract
Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract Open
View article: Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis
Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis Open
View article: TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models
TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models Open
Toll-like receptor (TLR) 4 agonists have emerged as a new group of molecules used for cancer therapy. They have been exploited to enhance the immunogenicity of current chemotherapeutic regimens. However, their effects on cancer cells remai…