Jesse B. Yoder
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View article: Detection and Tracking of SARS-CoV-2 Lineages through National Wastewater Surveillance System Pathogen Genomics
Detection and Tracking of SARS-CoV-2 Lineages through National Wastewater Surveillance System Pathogen Genomics Open
We conducted retrospective analysis of the emergence of the SARS-CoV-2 JN.1 variant in US wastewater during November 2023-July 2024 using Aquascope, a bioinformatics pipeline for the National Wastewater Surveillance System. This study high…
View article: Metal‐Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction
Metal‐Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction Open
DNA double helices containing metal‐mediated DNA (mmDNA) base pairs are constructed from Ag + and Hg 2+ ions between pyrimidine:pyrimidine pairs with the promise of nanoelectronics. Rational design of mmDNA nanomaterials is impractical wit…
View article: Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation
Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation Open
Voltage-gated sodium channels (NaVs) are membrane proteins responsible for the rapid upstroke of the action potential in excitable cells. There are nine human voltage-sensitive NaV1 isoforms that, in addition to their sequence differences,…
View article: Nanobodies for isoform-specific study of voltage-gated sodium channels (Navs)
Nanobodies for isoform-specific study of voltage-gated sodium channels (Navs) Open
Nav1.4 and Nav1.5 are voltage-gated sodium channels that play an important role in the generation of action potential in excitable tissues.Navs control the passage of sodium ions into cells in response to changes in cellular membrane poten…
View article: Bilobal architecture is a requirement for calmodulin signaling to Ca<sub>V</sub>1.3 channels
Bilobal architecture is a requirement for calmodulin signaling to Ca<sub>V</sub>1.3 channels Open
Significance Calmodulin (CaM) regulation of voltage-gated calcium (Ca V ) channels constitutes a prototypic biological feedback mechanism that contributes prominently toward Ca 2+ homeostasis in neurons and cardiac myocytes. Here, by parti…