Jesse Cottrell
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View article: Cigarette use and smoking cessation goals among pregnant women with opioid use disorder
Cigarette use and smoking cessation goals among pregnant women with opioid use disorder Open
gov; Identifier: NCT03918850.
View article: Maternal and Neonatal Outcomes in Gestational Hypertension for Delivery at 37 versus 38 to 40 Weeks
Maternal and Neonatal Outcomes in Gestational Hypertension for Delivery at 37 versus 38 to 40 Weeks Open
This study aimed to compare neonatal and maternal outcomes for mothers with gestational hypertension delivered at 37 weeks' gestation compared with 38 to 40 weeks. Single-center, retrospective chart review of women with gestational hyperte…
View article: Progesterone‐induced blocking factor blockade causes hypertension in pregnant rats
Progesterone‐induced blocking factor blockade causes hypertension in pregnant rats Open
Preeclampsia (PE) is a multisystem disorder characterized by new onset hypertension in mid‐late gestation and can include multi‐organ dysfunction with or without proteinuria. It affects 5%–7% of all pregnancies in the U.S., making PE a maj…
View article: Discontinuation of Routine Postpartum Complete Blood Count in Uncomplicated Vaginal Deliveries
Discontinuation of Routine Postpartum Complete Blood Count in Uncomplicated Vaginal Deliveries Open
The aim of this prospective study is to assess the clinical utility and safety of discontinuing routine Complete Blood Count (CBC) testing in uncomplicated vaginal deliveries with a focus on identifying potential benefits, risks, and overa…
View article: Examination of cord blood at birth in women with SARS-CoV-2 exposure and/or vaccination during pregnancy and relationship to fetal complete blood count, cortisol, ferritin, vitamin D, and CRP
Examination of cord blood at birth in women with SARS-CoV-2 exposure and/or vaccination during pregnancy and relationship to fetal complete blood count, cortisol, ferritin, vitamin D, and CRP Open
Background SARS-CoV-2 is known to manifest a robust innate immune response. However, little is known about inflammatory influences from maternal SARS-CoV-2 infection or maternal mRNA vaccination upon the fetus. In addition, it is unknown i…
View article: Triple Positive Antiphospholipid Antibody Syndrome in Pregnancy with High Frequency Plasma Exchange: A Case Report
Triple Positive Antiphospholipid Antibody Syndrome in Pregnancy with High Frequency Plasma Exchange: A Case Report Open
Introduction: Triple antibody positive antiphospholipid syndrome during pregnancy carries a poor prognosis. The placental vasculature is particularly vulnerable to these antibodies resulting in a marked increased risk of fetal growth restr…
View article: Delayed Complete Chorioamniotic Membrane Separation in the Third Trimester Following a Motor Vehicle Collision
Delayed Complete Chorioamniotic Membrane Separation in the Third Trimester Following a Motor Vehicle Collision Open
Complete separation of the amnion and chorion is a rare pregnancy complication. The proposed causes for chorioamniotic separation are failure of fusion,spontaneous separation, and iatrogenically from invasive prenatal pro-cedures. We prese…
View article: Syphilis and Proteinuria in Pregnancy
Syphilis and Proteinuria in Pregnancy Open
Syphilis has the potential to result in serious irreversible morbidity and mortality during pregnancy and has been increasing in incidence across the United States. While syphilis is a common disease and a known but rare cause of membranou…
View article: Cardiodynamic Profiles of Gravidas with Obesity in Early Gestation
Cardiodynamic Profiles of Gravidas with Obesity in Early Gestation Open
Background Obesity is a significant contributor to adverse maternal and perinatal outcomes, increasing the risk of spontaneous miscarriage, stillbirth, preterm delivery, fetal malformations, gestational diabetes, fetal macrosomia, cesarean…
View article: The effect of impedance cardiography directed antihypertensive therapy on fetal growth restriction rates and perinatal mortality in women with chronic hypertension
The effect of impedance cardiography directed antihypertensive therapy on fetal growth restriction rates and perinatal mortality in women with chronic hypertension Open
The rates of IUGR and perinatal mortality did not increase even with increasing severity of maternal hypertension. This low cost and non-invasive test should be considered for optimizing rates of growth restriction and perinatal mortality …
View article: Progesterone-induced blocking factor improves blood pressure, inflammation, and pup weight in response to reduced uterine perfusion pressure (RUPP)
Progesterone-induced blocking factor improves blood pressure, inflammation, and pup weight in response to reduced uterine perfusion pressure (RUPP) Open
Preeclampsia (PE) is characterized by new-onset hypertension in association with elevated natural killer (NK) cells and inflammatory cytokines, which are likely culprits for decreased fetal weight during PE pregnancies. As progesterone inc…
View article: Characterization of Fetal Thyroid Levels at Delivery among Appalachian Infants
Characterization of Fetal Thyroid Levels at Delivery among Appalachian Infants Open
Thyroid disorders are a frequently encountered issue during pregnancy and a cause of maternal and fetal morbidity. In regions like Appalachia that are particularly susceptible to health disparities, descriptive studies are needed to assist…
View article: Successful treatment of a cervical ectopic pregnancy with single-dose methotrexate therapy
Successful treatment of a cervical ectopic pregnancy with single-dose methotrexate therapy Open
Ectopic pregnancies implanted in the cervix account for less than one percent of all extra-uterine pregnancies. Due to the rare incidence of cervical ectopic pregnancies, there are no established guidelines for medical versus surgical mana…
View article: Aortic Dissections in Marfan Disease During Pregnancy: Review Article
Aortic Dissections in Marfan Disease During Pregnancy: Review Article Open
We want to thank Dr. Raveenthiran and Dr. Harky for their interest in our paper and in the topic of Marfans in the setting of pregnancy. Certainly, the reduction of adverse outcomes would be improved with early knowledge of Marfans syndrom…
View article: Interleukin-4 supplementation improves the pathophysiology of hypertension in response to placental ischemia in RUPP rats
Interleukin-4 supplementation improves the pathophysiology of hypertension in response to placental ischemia in RUPP rats Open
Preeclampsia (PE) is characterized by chronic inflammation and elevated agonistic autoantibodies to the angiotensin type 1 receptor (AT 1 -AA), endothelin-1, and uterine artery resistance index (UARI) during pregnancy. Previous studies rep…
View article: Inflammatory mediators: a causal link to hypertension during preeclampsia
Inflammatory mediators: a causal link to hypertension during preeclampsia Open
Preeclampsia (PE) is a hypertensive disorder that occurs after 20 weeks of gestation, implicating the placenta as a key offender. PE is associated with an imbalance among B lymphocytes, CD4 + T lymphocytes, NK cells and increased inflammat…
View article: The Effect of Hepatitis C on Maternal Bile Acid Level and the Fetal Left Ventricular Tei Index
The Effect of Hepatitis C on Maternal Bile Acid Level and the Fetal Left Ventricular Tei Index Open
Hepatitis C (HCV) is a common form of liver disease encountered in pregnancy. The purpose of this study is to evaluate if hepatitis C is associated with elevated maternal serum bile acids and abnormal fetal cardiac function measured by the…
View article: Rural versus Urban Umbilical Cord Blood Vitamin D Levels at Parturition in Appalachia
Rural versus Urban Umbilical Cord Blood Vitamin D Levels at Parturition in Appalachia Open
The aim of this study was to compare fetal cord blood levels of vitamin D in rural versus urban areas in the Appalachian region. There is a positive correlation between maternal and cord blood vitamin D levels, and prior studies have show…
View article: Self-Reported Tobacco Use and Correlation with Umbilical Cord Blood Cotinine levels at Delivery among Appalachian Gravidas
Self-Reported Tobacco Use and Correlation with Umbilical Cord Blood Cotinine levels at Delivery among Appalachian Gravidas Open
The detrimental effects of cigarette use during pregnancy are well documented. Studies have shown that cigarette smoking while pregnant is associated with multiple adverse outcomes including: pre-term birth, placental abruption, placenta p…