Jesse K. McKenney
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View article: In reply to: ‘Prostate cancer with favorable histology is not synonymous with prostate cancer indolence’
In reply to: ‘Prostate cancer with favorable histology is not synonymous with prostate cancer indolence’ Open
View article: Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer Open
Continued reliance on the androgen receptor (AR) after androgen deprivation therapy (ADT) fails causes 35,000 American prostate cancer (CaP) deaths annually. Targeting the AR's transcriptional activity could overcome this acquired resistan…
View article: Classification of prostatic adenocarcinoma as favourable/unfavourable histology has high interobserver agreement in prostate needle core biopsies
Classification of prostatic adenocarcinoma as favourable/unfavourable histology has high interobserver agreement in prostate needle core biopsies Open
Aims A dichotomous classifier for prostatic adenocarcinoma, favourable and unfavourable histology, was recently proposed to optimize metastasis prediction. We evaluate interobserver agreement for its classification. Methods and results Fif…
View article: Acceptance of emerging renal oncocytic neoplasms: a survey of urologic pathologists
Acceptance of emerging renal oncocytic neoplasms: a survey of urologic pathologists Open
Oncocytic renal neoplasms are a major source of diagnostic challenge in genitourinary pathology; however, they are typically nonaggressive in general, raising the question of whether distinguishing different subtypes, including emerging en…
View article: Impact of pathologic re-review on grade, clinical stage, and risk stratification for patients with nonmuscle invasive bladder cancer
Impact of pathologic re-review on grade, clinical stage, and risk stratification for patients with nonmuscle invasive bladder cancer Open
Re-review of TURBT pathology by a dedicated GU pathologist led to change in AUA NMIBC risk stratification in over one-fifth of patients, with potential for changing management.
View article: Long-Term Outcomes in Patients Using Protocol-Directed Active Surveillance for Prostate Cancer
Long-Term Outcomes in Patients Using Protocol-Directed Active Surveillance for Prostate Cancer Open
Importance Outcomes from protocol-directed active surveillance for favorable-risk prostate cancers are needed to support decision-making. Objective To characterize the long-term oncological outcomes of patients receiving active surveillanc…
View article: High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker
High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker Open
Distinguishing indolent from clinically significant localized prostate cancer is a major clinical challenge and influences clinical decision-making between treatment and active surveillance. The development of novel predictive biomarkers w…
View article: Supplementary Figure 1 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 1 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 1
View article: Supplementary Figure 7 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 7 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 7
View article: Supplementary Figure 1 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 1 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 1
View article: Supplementary Information from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Information from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Information file
View article: Supplementary Figure 6 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 6 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 6
View article: Supplementary Figure 4 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 4 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 4
View article: Data from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Data from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Prostate cancer remains the second leading cause of cancer death in men in Western cultures. A deeper understanding of the mechanisms by which prostate cancer cells divide to support tumor growth could help devise strategies to overcome tr…
View article: Supplementary Figure 6 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 6 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 6
View article: Supplementary Figure 5 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 5 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 5
View article: Supplementary Figure 3 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 3 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 3
View article: Supplementary Information from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Information from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Information file
View article: Supplementary Figure 5 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 5 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 5
View article: Data from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Data from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Prostate cancer remains the second leading cause of cancer death in men in Western cultures. A deeper understanding of the mechanisms by which prostate cancer cells divide to support tumor growth could help devise strategies to overcome tr…
View article: Supplementary Figure 2 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 2 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 2
View article: Supplementary Figure 2 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 2 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 2
View article: Supplementary Figure 7 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 7 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 7
View article: Supplementary Figure 3 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 3 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 3
View article: Supplementary Figure 4 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Supplementary Figure 4 from Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase Open
Supplementary Figure 4
View article: Hybrid Oncocytic Tumors (HOTs) in Birt-Hogg-Dubé Syndrome Patients—A Tale of Two Cities
Hybrid Oncocytic Tumors (HOTs) in Birt-Hogg-Dubé Syndrome Patients—A Tale of Two Cities Open
Birt-Hogg-Dubé (BHD) syndrome is associated with an increased risk of multifocal renal tumors, including hybrid oncocytic tumor (HOT) and chromophobe renal cell carcinoma (chRCC). HOT exhibits heterogenous histologic features overlapping w…
View article: Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome Open
View article: Anastomosing haemangioma of the adrenal gland: A clinicopathological series of seven cases
Anastomosing haemangioma of the adrenal gland: A clinicopathological series of seven cases Open
Aims Anastomosing haemangioma is a rare benign vascular neoplasm that may histologically mimic angiosarcoma. We report the largest single institution series of anastomosing haemangioma in the adrenal gland with emphasis on clinical and rad…
View article: Artificial Intelligence-Based PTEN Loss Assessment as an Early Predictor of Prostate Cancer Metastasis After Surgery: A Multicenter Retrospective Study
Artificial Intelligence-Based PTEN Loss Assessment as an Early Predictor of Prostate Cancer Metastasis After Surgery: A Multicenter Retrospective Study Open
View article: Supplementary Tables S1 - S6 from Biallelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney
Supplementary Tables S1 - S6 from Biallelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney Open
Supplementary Tables S1 - S6. Supplementary Table S1. Patient clinical characteristics and summary of the observed molecular aberrations in the MTSCC cases studied. Supplementary Table S2. Sequencing quality metrics. Supplementary Table S3…