Explanipedia

Electrical Stimulation for the Induction of Seizures is Safe, Well-tolerated and High-Yield in Children with Drug-Resistant Epilepsy Open

Lucy Tarcha, Darcy A. Krueger, Hansel M. Greiner, Jesse Skoch, Francesco T. Mangano , et al. · 2025

Introduction One third of children with epilepsy develop drug-resistant epilepsy (DRE). Epilepsy surgery is the treatment for DRE, and selecting the surgical target typically requires recording spontaneous seizures during intracranial moni…

Drug Induced Sleep Endoscopy to Evaluate Vagus Nerve Stimulator Effects on Upper Airway Dynamics Open

Raisa Tikhtman, Soraya Abdul-Hadi, Kathleen M. Sarber, Christopher Carosella, Wei Liu , et al. · 2025

High‐gamma modulation language mapping and cognitive outcomes after epilepsy surgery Open

Brian Ervin, Christina Kargol, Anna W. Byars, Jason Buroker, Leonid Rozhkov , et al. · 2024

Objective We evaluated changes in cognitive domains after neurosurgical lesioning of cortical sites with significant high‐gamma power modulations (HGM) during a visual naming task, although these sites were found language‐negative on stand…

MRI and pathology comparisons in Rasmussen’s encephalitis: a multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity Open

Alexander Doherty, Kathleen Knudson, Christine Fuller, James L. Leach, Anthony Wang , et al. · 2024

Purpose Rasmussen encephalitis (RE) is a very rare chronic neurological disorder of unilateral inflammation of the cerebral cortex. Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant r…

Editorial: Magnetic resonance-guided laser interstitial thermal therapy (MRg-LiTT) in the minimally invasive surgical treatment of epilepsy and/or brain neoplasms Open

Alessandro Consales, Jesse Skoch, Zulma Tovar-Spinoza · 2024

Editorial: Magnetic resonance-guided laser interstitial thermal therapy (MRg-LiTT) in the minimally invasive surgical treatment of epilepsy and/or brain neoplasms

MRI and pathology comparisons in Rasmussen’s Encephalitis: A multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity Open

Alexander Doherty, Kathleen Knudson, Christine Fuller, James L. Leach, Anthony Wang , et al. · 2024

Purpose Rasmussen encephalitis (RE) is a very rare chronic neurological disorder of unilateral inflammation of the cerebral cortex. Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant r…

Neuropsychological outcomes after epilepsy surgery: A comparison of stereo electroencephalography and subdural electrodes Open

Ravindra Arya, Clayton Frink, Christina Kargol, Anna W. Byars, David A. Huddleston , et al. · 2023

Background and purpose We analyzed the association of neuropsychological outcomes after epilepsy surgery with the intracranial electrode type (stereo electroencephalography [SEEG] and subdural electrodes [SDE]), and electrical stimulation …

Comparing electrical stimulation functional mapping with subdural electrodes and stereoelectroencephalography Open

Gewalin Aungaroon, Kishore Vedala, Anna W. Byars, Brian Ervin, Leonid Rozhkov , et al. · 2023

Objective Electrical stimulation mapping (ESM) is the clinical standard for functional localization with subdural electrodes (SDE). As stereoelectroencephalography (SEEG) has emerged as an alternative option, we compared functional respons…

Comparison of outcomes after stereoelectroencephalography and subdural grid monitoring in pediatric tuberous sclerosis complex Open

Thomas Larrew, Jesse Skoch, S. Katie Z. Ihnen, Ravindra Arya, Katherine D. Holland , et al. · 2022

OBJECTIVE Patients with tuberous sclerosis complex (TSC) epilepsy present with unique clinical challenges such as early seizure onset and high rates of intractability and multifocality. Although there are numerous studies about the safety …

Posterior Quadrant Disconnection Procedure for Intractable Epilepsy: A Case Series of 5 Young Pediatric Patients Open

Smruti Patel, Justin Gibson, Mykhailo Lovha, James L. Leach, Ravindra Arya , et al. · 2022

BACKGROUND: Posterior quadrant disconnection (PQD) has been described as a treatment for patients with refractory posterior quadrant subhemispheric epilepsy. Surgical outcomes are difficult to interpret because of limited literature. OBJEC…

Exclusively endoscopic management of complicated pineal cysts in young children: Definitive treatment through single burr-hole technique Open

Baher Hanna, Michael Robinson, Jesse Skoch · 2022

Background: The management of complicated symptomatic pineal cysts in the pediatric population is challenging and variable. Surgical management may include treatment of hydrocephalus alone, or direct treatment of the cyst with or without d…

Neuronal Circuits Supporting Development of Visual Naming Revealed by Intracranial Coherence Modulations Open

Ravindra Arya, Brian Ervin, Jason Buroker, Hansel M. Greiner, Anna W. Byars , et al. · 2022

Background Improvement in visual naming abilities throughout the childhood and adolescence supports development of higher-order linguistic skills. We investigated neuronal circuits underlying improvement in the speed of visual naming with …

Partial suturectomy for phenotypical craniosynostosis caused by incomplete fusion of cranial sutures: a novel surgical solution Open

David C. Lobb, Smruti Patel, Brian S. Pan, Jesse Skoch · 2021

OBJECTIVE Patients presenting with head shape changes phenotypical for craniosynostosis may have incomplete fusion of the involved sutures. The surgical literature is lacking in appropriate management strategies for these patients. In this…

Evaluation of smartphone-integrated magnetometers in detection of safe electromagnetic devices for use near programmable shunt valves: a proof-of-concept study Open

Smruti Patel, J. Fernández, Carlie McCoy, Jesse Skoch · 2021

OBJECTIVE External magnetic forces can have an impact on programmable valve mechanisms and potentially alter the opening pressure. As wearable technology has begun to permeate mainstream living, there is a clear need to provide information…

Neuro-Ophthalmological Manifestations of Craniosynostosis: Current Perspectives Open

Michael Duan, Jesse Skoch, Brian S. Pan, Veeral Shah · 2021

Craniosynostosis, a premature fusion of cranial sutures that can be isolated or syndromic, is a congenital defect with a broad, multisystem clinical spectrum. The visual pathway is prone to derangements in patients with craniosynostosis, p…

S1-17 ENDOSCOPIC ENDONASAL APPROACH FOR THE RESECTION OF NASAL DERMOID CYSTS WITH INTRACRANIAL EXTENSION Open

J. A. Lee, Susanne C. Monahan, S. Vuong, Dani Smith, Haithem Babiker , et al. · 2019

Introduction: Nasal dermoid cysts with intracranial extension are generally treated via an open approach with bicoronal exposure and craniotomy, providing visualization of the intracranial extension. Here we present an alternative multidis…

S9A-01 SESSION 9A: CRANIOPLASTY BONE MORPHOGENETIC PROTEIN-2 IN PEDIATRIC CRANIOPLASTY Open

Casey Jones, Shilpa Shah, Brian S. Pan, Padmaja K. Naidu, William T. O’Brien , et al. · 2019

Introduction: In pediatric cranioplasty, challenges include a diploic space too thin for split calvarial grafting, and alloplastic materials prone to infection, extrusion, or improper fit. Bone morphogenetic protein-2 (BMP-2) may present a…

Successful Whole Genome Sequencing-guided Treatment of Mycoplasma hominis Ventriculitis in a Preterm Infant Open

Felicia A. Scaggs Huang, Joel E. Mortensen, Jesse Skoch, Heidi Andersen, Mary Allen Staat , et al. · 2019

We report a case of Mycoplasma hominis ventriculitis in a preterm neonate that was successfully identified with 16S ribosomal RNA sequencing and whole genome sequencing after failure to detect the pathogen with conventional diagnostic meth…

Deep brain stimulation of a patient with psychogenic movement disorder Open

Jean‐Philippe Langevin, Jesse Skoch, Scott J. Sherman · 2016

We argue that the absence of side effects, the normal DaTscan, and PET scan after 5 years of chronic stimulation illustrate the safety of DBS on neural tissue.

Combined posterior hemiosteotomies and stabilization with lateral thoracotomy for en bloc resection of thoracic paraspinal primary bone tumors: technical note Open

Mauricio J. Ávila, Jesse Skoch, Vernard S. Fennell, Sheri K. Palejwala, Christina M. Walter , et al. · 2015

Primary bone tumors of the spine are rare entities with a poor prognosis if left untreated. En bloc excision is the preferred surgical approach to minimize the rate of recurrence. Paraspinal primary bone tumors are even less common. In thi…

Augmented microscopy: real-time overlay of bright-field and near-infrared fluorescence images Open

Jeffrey R. Watson, Christian F. Gainer, Nikolay L. Martirosyan, Jesse Skoch, Gerald M. Lemole , et al. · 2015

Intraoperative applications of near-infrared (NIR) fluorescent contrast agents can be aided by instrumentation capable of merging the view of surgical field with that of NIR fluorescence. We demonstrate augmented microscopy, an intraoperat…

Freehand Thoracic Pedicle Screw Placement Techniques: A Comprehensive Review of Safety and Efficacy Open

Kamran Sattarov, Jesse Skoch, Mauricio J. Ávila, Salman Abbasifard, Apar S. Patel , et al. · 2015

Introduction Freehand techniques for thoracic pedicle screw placement have gained popularity as they reduce intraoperative radiation exposure and overall operative time. The goal of this work is to present our technique as well as systemat…

Removal of symptomatic craniofacial titanium hardware following craniotomy: Case series and review Open

Sheri K. Palejwala, Jesse Skoch, Gerald M. Lemole · 2015

Titanium craniofacial hardware has become commonplace for reconstruction and bone flap fixation following craniotomy. Complications of titanium hardware include palpability, visibility, infection, exposure, pain, and hardware malfunction, …

Integration of Indocyanine Green Videoangiography With Operative Microscope Open

Nikolay L. Martirosyan, Jesse Skoch, Jeffrey R. Watson, Gerald M. Lemole, Marek Romanowski , et al. · 2015

The overlay of fluorescence videoangiography within the field of view of the white light operative microscope allows real-time assessment of the blood flow within vessels during simultaneous surgical manipulation. This technique could impr…

A paradigm for the evaluation and management of spinal coccidioidomycosis Open

AliA Baaj, NikolayL Martirosyan, Jesse Skoch, Orel A. Zaninovich, Carmine Zoccali , et al. · 2015

This work provides a working protocol involving assessment and reassessment for the management of spinal coccidioidomycosis. Medical management with antifungal agents in some cases can provide satisfactory disease control. However, in pati…

Posterior atlantoaxial fixation: A cadaveric and fluoroscopic step-by-step technical guide Open

AliA Baaj, Kamran Sattarov, Jesse Skoch, Salman Abbasifard, A Patel , et al. · 2015

Given the widespread utilization of this technique, described step-by-step guide is timely for surgeons and trainees alike.

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