Jessica Dougherty
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View article: Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure
Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure Open
Objective MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression and remain stable in biological fluids, even under harsh conditions. Their stability and responsiveness to environmental stressors make them str…
View article: Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial–Mesenchymal Transition
Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial–Mesenchymal Transition Open
Radiation resistance presents a significant challenge in the treatment of triple-negative breast cancer (TNBC). To investigate the molecular adaptations associated with radiation therapy resistance, MDA-MB-231 cells were subjected to a rep…
View article: FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks
FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks Open
Purpose FOS-like antigen 1 (FRA1), encoded by FOSL1 , is an inducible subunit of the AP-1 transcription factor complex and regulates gene expression in response to proliferative and environmental cues. Although FRA1 has been linked to canc…
View article: Metabolism of Terephthalic Acid by a Novel Bacterial Consortium Produces Valuable By-Products
Metabolism of Terephthalic Acid by a Novel Bacterial Consortium Produces Valuable By-Products Open
Terephthalic acid (TPA), a major monomer of polyethylene terephthalate (PET), represents a significant challenge in plastic waste management due to its persistence in the environment. In this study, we report a newly developed bacterial co…
View article: A Conceptual Framework Supporting Translanguaging Pedagogies in Secondary Dual-Language Programs
A Conceptual Framework Supporting Translanguaging Pedagogies in Secondary Dual-Language Programs Open
This article summarizes the literature on the design of a conceptual framework for secondary translanguaging classrooms. As school districts move to expand dual language programs beyond elementary schools, they are obligated to ensure that…
View article: Acute Impacts of Ionizing Radiation Exposure on the Gastrointestinal Tract and Gut Microbiome in Mice
Acute Impacts of Ionizing Radiation Exposure on the Gastrointestinal Tract and Gut Microbiome in Mice Open
Radiation therapy for abdominopelvic malignancies often results in damage to the gastrointestinal tract (GIT) and permanent changes in bowel function. An overlooked component of the pathophysiology of radiation-induced bowel injury is the …
View article: Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression
Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression Open
FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily. FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in response to extracellular signals, leading to downstream…
View article: Using SFL-based text analysis to inform instruction for emergent bilingual learners
Using SFL-based text analysis to inform instruction for emergent bilingual learners Open
Emergent Bilingual Learners (EBs) need language-focused instructional support if they are to access content, make meaning, and engage critically with academic texts in English. Text analysis informed by systemic functional linguistics (SFL…
View article: A Microethnographic Study of Bilingual Teacher Candidates' Appropriation of Translanguaging
A Microethnographic Study of Bilingual Teacher Candidates' Appropriation of Translanguaging Open
Preparing bilingual teacher candidates is an important task for teacher preparation programs as bilingual education is a growing field. In order to become culturally and linguistically responsive teachers, bilingual teacher candidates need…