Jessica E. Ericson
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View article: Critical genomic insights into vancomycin-resistant <i>Enterococcus faecium</i> in Lebanon
Critical genomic insights into vancomycin-resistant <i>Enterococcus faecium</i> in Lebanon Open
Vancomycin-resistant Enterococcus faecium (VRE) poses a global public health threat, with particularly severe ramifications in low-resource settings. While E. faecium is commonly a commensal organism in the human gut, the acquisition of va…
View article: Poor Surgical Outcomes Following<i>Paenibacillus</i>Infant Infectious Hydrocephalus
Poor Surgical Outcomes Following<i>Paenibacillus</i>Infant Infectious Hydrocephalus Open
Objective We previously identified Paenibacillus species in the cerebrospinal fluid of 44% of infants presenting for neurosurgical evaluation with findings consistent with postinfectious hydrocephalus (PIH) in Eastern Uganda. Here we sough…
View article: Preconception and Prenatal Environment and Growth Faltering Among Children in Uganda
Preconception and Prenatal Environment and Growth Faltering Among Children in Uganda Open
Importance Children with growth faltering are more susceptible to infections and may experience cognitive, physical, and metabolic developmental impairments. Objective To assess whether prenatal and preconception meteorological and environ…
View article: Future actions for the ocean acidification research community to support marine industries and coastal communities of Aotearoa New Zealand
Future actions for the ocean acidification research community to support marine industries and coastal communities of Aotearoa New Zealand Open
View article: P-1158. Surgical Outcomes Following <i>Paenibacillus</i> Infant Infectious Hydrocephalus
P-1158. Surgical Outcomes Following <i>Paenibacillus</i> Infant Infectious Hydrocephalus Open
Background We previously identified Paenibacillus species in the cerebrospinal fluid of 44% of infants presenting for neurosurgical evaluation with findings consistent with postinfectious hydrocephalus (PIH) in Eastern Uganda. Here we soug…
View article: Case Report: Successful avoidance of etoposide for primary hemophagocytic lymphohistiocytosis-induced multiple organ dysfunction syndrome using emapalumab
Case Report: Successful avoidance of etoposide for primary hemophagocytic lymphohistiocytosis-induced multiple organ dysfunction syndrome using emapalumab Open
We describe the case of an infant who presented with simple rhinovirus/enterovirus bronchiolitis whose condition worsened with rapid progression to multiple organ dysfunction syndrome (MODS). The patient was presumed to have either primary…
View article: 422. Impact of Respiratory Virus Co-Infection in Pediatric COVID-19
422. Impact of Respiratory Virus Co-Infection in Pediatric COVID-19 Open
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral infection that emerged in December 2019, leading to the COVID-19 pandemic. Despite significant research, there are still significant knowledge gaps, particu…
View article: Human<i>Paenibacillus</i>Infections: A Systematic Review with Comparison of Adult and Infant Cases
Human<i>Paenibacillus</i>Infections: A Systematic Review with Comparison of Adult and Infant Cases Open
Neonatal infections due to Paenibacillus species have increasingly been reported over the last few years. We performed a structured literature review of human Paenibacillus infections in infants and adults to compare the epidemiology of in…
View article: Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study
Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study Open
National Institutes of Health and Boston Children's Hospital Office of Faculty Development.
View article: Neonatal Paenibacilliosis: <i>Paenibacillus</i> Infection as a Novel Cause of Sepsis in Term Neonates With High Risk of Sequelae in Uganda
Neonatal Paenibacilliosis: <i>Paenibacillus</i> Infection as a Novel Cause of Sepsis in Term Neonates With High Risk of Sequelae in Uganda Open
Background Paenibacillus thiaminolyticus may be an underdiagnosed cause of neonatal sepsis. Methods We prospectively enrolled a cohort of 800 full-term neonates presenting with a clinical diagnosis of sepsis at 2 Ugandan hospitals. Quantit…
View article: Prolonged Thrombocytopenia in a Case of MIS-C in a Vaccinated Child
Prolonged Thrombocytopenia in a Case of MIS-C in a Vaccinated Child Open
Multisystem inflammatory syndrome in children (MIS-C) has been extensively described in patients following severe acute respiratory syndrome coronavirus 2 infection. There are now questions about what MIS-C may look like in vaccinated chil…
View article: 1328. Paenibacillosis: An Emerging Cause of Neonatal Sepsis and Postinfectious Hydrocephalus
1328. Paenibacillosis: An Emerging Cause of Neonatal Sepsis and Postinfectious Hydrocephalus Open
Background The etiology of neonatal sepsis is often not identified. Molecular methods can identify pathogens that culture-based methods miss. Most cases of neonatal sepsis globally are treated empirically per WHO guidelines with intravenou…
View article: 1084. Comparison of Pediatric SARS-CoV-2 Infections During Spring 2020 and Spring 2021
1084. Comparison of Pediatric SARS-CoV-2 Infections During Spring 2020 and Spring 2021 Open
Background Data is lacking regarding the clinical manifestations of children with SARS-CoV-2 infection during Spring 2021 and how that clinical presentation compares to children who presented during the early months of the pandemic. We sou…
View article: Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus
Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus Open
Postinfectious hydrocephalus, a devastating sequela of neonatal infection, is associated with increased childhood mortality and morbidity. A novel bacterial pathogen, Paenibacillus thiaminolyticus , is highly associated with postinfectious…
View article: Neonatal Paenibacilliosis:<i>Paenibacillus thiaminolyticus</i>as a Novel Cause of Neonatal Sepsis with High Risk of Sequelae in Uganda
Neonatal Paenibacilliosis:<i>Paenibacillus thiaminolyticus</i>as a Novel Cause of Neonatal Sepsis with High Risk of Sequelae in Uganda Open
Paenibacillus thiaminolyticus may be an underdiagnosed cause of neonatal sepsis. We prospectively enrolled a cohort of 800 neonates presenting with a clinical diagnosis of sepsis at two Ugandan hospitals. Quantitative polymerase chain reac…
View article: Exposure-safety relationship for acyclovir in the treatment of neonatal herpes simplex virus disease
Exposure-safety relationship for acyclovir in the treatment of neonatal herpes simplex virus disease Open
View article: Solithromycin in Children and Adolescents With Community-acquired Bacterial Pneumonia
Solithromycin in Children and Adolescents With Community-acquired Bacterial Pneumonia Open
Background: Solithromycin is a new macrolide-ketolide antibiotic with potential effectiveness in pediatric community-acquired bacterial pneumonia (CABP). Our objective was to evaluate its safety and effectiveness in children with CABP. Met…
View article: Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus
Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus Open
View article: Type IV pili is a critical virulence factor in clinical isolates of<i>Paenibacillus thiaminolyticus</i>
Type IV pili is a critical virulence factor in clinical isolates of<i>Paenibacillus thiaminolyticus</i> Open
Hydrocephalus, the leading indication for childhood neurosurgery worldwide, is particularly prevalent in low-and-middle-income countries (LMICs). Hydrocephalus preceded by an infection, or postinfectious hydrocephalus (PIH), accounts for u…
View article: <i>Paenibacillus</i> Infection Causes Neonatal Sepsis and Subsequent Postinfectious Hydrocephalus in Ugandan Infants
<i>Paenibacillus</i> Infection Causes Neonatal Sepsis and Subsequent Postinfectious Hydrocephalus in Ugandan Infants Open
View article: 1133. Opportunities for Antibiotic Discontinuation and De-escalation after Discharge from the Emergency Department in Pediatric Patients with UTI
1133. Opportunities for Antibiotic Discontinuation and De-escalation after Discharge from the Emergency Department in Pediatric Patients with UTI Open
Background In children, urinary tract infection (UTI) represents one of the most common indications for antibiotics. While previous data has demonstrated high rates of misdiagnosis and inconsistencies with empiric antibiotics, the impact a…
View article: 486. Characteristics Associated with SARS-CoV-2 Infection in Children
486. Characteristics Associated with SARS-CoV-2 Infection in Children Open
Background We sought to describe the range of Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in children. Methods Patients < 18 years of age who had a positive nasopharyngeal polymerase chain reaction (PCR) for SARS-CoV…
View article: Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection
Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection Open
In this systematic review, more than half of COVID-19 survivors experienced PASC 6 months after recovery. The most common PASC involved functional mobility impairments, pulmonary abnormalities, and mental health disorders. These long-term …
View article: Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries With Universal Screening
Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries With Universal Screening Open
In this meta-analysis, LMICs appeared to incur the most significant infection burden. Lower rates of cCMV were reported by studies using only blood or serum as a screening method.
View article: Correction: Association of vitamin A deficiency with early childhood stunting in Uganda: A population-based cross-sectional study
Correction: Association of vitamin A deficiency with early childhood stunting in Uganda: A population-based cross-sectional study Open
[This corrects the article DOI: 10.1371/journal.pone.0233615.].
View article: Immune activation during Paenibacillus brain infection in African infants with frequent cytomegalovirus co-infection
Immune activation during Paenibacillus brain infection in African infants with frequent cytomegalovirus co-infection Open
View article: Global, regional and national epidemiology and prevalence of child stunting, wasting and underweight in low- and middle-income countries, 2006–2018
Global, regional and national epidemiology and prevalence of child stunting, wasting and underweight in low- and middle-income countries, 2006–2018 Open
View article: Severe Pediatric Mycoplasma pneumoniae Infection Requiring Veno-venous Extracorporeal Membrane Oxygenation
Severe Pediatric Mycoplasma pneumoniae Infection Requiring Veno-venous Extracorporeal Membrane Oxygenation Open
Mycoplasma pneumoniae (MP ) is an atypical bacterial pathogen that typically causes mild respiratory symptoms. Rarely, MP is associated with acute respiratory distress syndrome, a condition marked by widespread inflammation in the lungs th…
View article: Cytomegalovirus Infections in Ugandan Infants:Newborns, Neonates with Sepsis and Infants with Hydrocephalus
Cytomegalovirus Infections in Ugandan Infants:Newborns, Neonates with Sepsis and Infants with Hydrocephalus Open
View article: Global and Regional Congenital Cytomegalovirus (CMV) Epidemiology and Burden: Systematic Review and Meta-Analysis
Global and Regional Congenital Cytomegalovirus (CMV) Epidemiology and Burden: Systematic Review and Meta-Analysis Open