Jessica M. Armstrong
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View article: Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia Open
The ubiquitous metabolite heme has diverse enzymatic and signalling functions in most mammalian cells. Cells can salvage heme from the extracellular environment or synthesise heme de novo from succinyl-CoA and glycine through a series of 8…