Jessica M. Healy
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View article: Estimating transmission pathways of COVID-19 in U.S. nursing homes
Estimating transmission pathways of COVID-19 in U.S. nursing homes Open
Background Pathogen transmission dynamics in nursing homes are unique due to the interactions between staff and residents. Understanding the differences in transmission rates between and among staff and residents can identify the transmiss…
View article: Kinetics of <scp>SARS</scp> ‐ <scp>CoV</scp> ‐2 Shedding in Nursing Home Residents and Staff
Kinetics of <span>SARS</span> ‐ <span>CoV</span> ‐2 Shedding in Nursing Home Residents and Staff Open
Background Nursing homes (NHs) were disproportionately affected by the COVID‐19 pandemic. However, little is known regarding the kinetics of SARS‐CoV‐2 shedding in NH residents and staff, which could inform treatment and infection preventi…
View article: P-1178. Trends in invasive methicillin-resistant <i>Staphylococcus aureus</i> infections among children in the United States, 2011–2021
P-1178. Trends in invasive methicillin-resistant <i>Staphylococcus aureus</i> infections among children in the United States, 2011–2021 Open
Background During 2005–2010, incidence of community-associated (CA) invasive methicillin-resistant Staphylococcus aureus (MRSA) infections among children was rising, whereas hospital-onset (HO) rates were unchanged except for a decline amo…
View article: Viral Kinetics of SARS-CoV-2 in Nursing Home Residents and Staff
Viral Kinetics of SARS-CoV-2 in Nursing Home Residents and Staff Open
Background: Nursing home (NH) residents are at high risk of COVID-19 from exposure to infected staff and other residents. Understanding SARS-CoV-2 viral RNA kinetics in residents and staff can guide testing, isolation, and return to work r…
View article: Regional impact of multidrug-resistant organism prevention bundles implemented by facility type: A modeling study
Regional impact of multidrug-resistant organism prevention bundles implemented by facility type: A modeling study Open
Background: Emerging multidrug-resistant organisms (MDROs), such as carbapenem-resistant Enterobacterales (CRE), can spread rapidly in a region. Facilities that care for high-acuity patients with longer stays may have a disproportionate im…
View article: Kinetics of SARS-CoV-2 Shedding in Nursing Home Residents and Staff
Kinetics of SARS-CoV-2 Shedding in Nursing Home Residents and Staff Open
View article: Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty
Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty Open
Our ability to forecast epidemics far into the future is constrained by the many complexities of disease systems. Realistic longer-term projections may, however, be possible under well-defined scenarios that specify the future state of cri…
View article: Modelling counterfactual incidence during the transition towards culture-independent diagnostic testing
Modelling counterfactual incidence during the transition towards culture-independent diagnostic testing Open
Background Culture-independent diagnostic testing (CIDT) provides rapid results to clinicians and is quickly displacing traditional detection methods. Increased CIDT use and sensitivity likely result in higher case detection but might also…
View article: Which factors had the greatest impact on the United States COVID-19 outbreak? An ecological assessment of mitigation behavior and policy contributions to reducing SARS-CoV-2 transmission in the US from September 2020 through November 2021
Which factors had the greatest impact on the United States COVID-19 outbreak? An ecological assessment of mitigation behavior and policy contributions to reducing SARS-CoV-2 transmission in the US from September 2020 through November 2021 Open
Introduction : United States’ jurisdictions implemented varied policies to slow SARS-CoV-2 transmission. Understanding patterns of these policies alongside individual’s behaviors can inform effective outbreak response. Methods : We estimat…
View article: Public health impact of the U.S. Scenario Modeling Hub
Public health impact of the U.S. Scenario Modeling Hub Open
Beginning in December 2020, the COVID-19 Scenario Modeling Hub has provided quantitative scenario-based projections for cases, hospitalizations, and deaths, aggregated across up to nine modeling groups. Projections spanned multiple months …
View article: Epidemiology and Antimicrobial Resistance of <i>Campylobacter</i> Infections in the United States, 2005–2018
Epidemiology and Antimicrobial Resistance of <i>Campylobacter</i> Infections in the United States, 2005–2018 Open
Background Campylobacter is the most common cause of bacterial diarrhea in the United States; resistance to macrolides and fluoroquinolones limits treatment options. We examined the epidemiology of US Campylobacter infections and changes i…
View article: Informing pandemic response in the face of uncertainty.<i>An evaluation of the U.S. COVID-19 Scenario Modeling Hub</i>
Informing pandemic response in the face of uncertainty.<i>An evaluation of the U.S. COVID-19 Scenario Modeling Hub</i> Open
Our ability to forecast epidemics more than a few weeks into the future is constrained by the complexity of disease systems, our limited ability to measure the current state of an epidemic, and uncertainties in how human action will affect…
View article: An interactive patient transfer network and model visualization tool for multidrug-resistant organism prevention strategies
An interactive patient transfer network and model visualization tool for multidrug-resistant organism prevention strategies Open
Background: The CDC’s new Public Health Strategies to Prevent the Spread of Novel and Targeted Multidrug-Resistant Organisms (MDROs) were informed by mathematical models that assessed the impact of implementing preventive strategies direct…
View article: How COVID-19 spread varied by resident length of stay and resident–staff transmission pathways over time in US nursing homes
How COVID-19 spread varied by resident length of stay and resident–staff transmission pathways over time in US nursing homes Open
Background: Pathogen transmission among staff and residents in nursing homes can vary depending on their interactions and by the amount of time a resident receives care in the facility. Understanding the relative differences in transmissio…
View article: Accounting for assay performance when estimating the temporal dynamics in SARS-CoV-2 seroprevalence in the U.S.
Accounting for assay performance when estimating the temporal dynamics in SARS-CoV-2 seroprevalence in the U.S. Open
View article: Impact of SARS-CoV-2 vaccination of children ages 5–11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021–March 2022: A multi-model study
Impact of SARS-CoV-2 vaccination of children ages 5–11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021–March 2022: A multi-model study Open
Background: The COVID-19 Scenario Modeling Hub convened nine modeling teams to project the impact of expanding SARS-CoV-2 vaccination to children aged 5–11 years on COVID-19 burden and resilience against variant strains. Methods: Teams con…
View article: Impact of SARS-CoV-2 vaccination of children ages 5–11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021–March 2022: a multi-model study
Impact of SARS-CoV-2 vaccination of children ages 5–11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021–March 2022: a multi-model study Open
Various (see acknowledgments).
View article: Accounting for assay performance when estimating the temporal dynamics in SARS-CoV-2 seroprevalence in the U.S
Accounting for assay performance when estimating the temporal dynamics in SARS-CoV-2 seroprevalence in the U.S Open
Estimating the incidence of SARS-CoV-2 infection is central to understanding the state of the pandemic. Seroprevalence studies are often used to assess cumulative infections as they can identify asymptomatic infection. Since July 2020, com…
View article: Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination
Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination Open
In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed vaccination uptake, this novel variant was expected t…
View article: Author response: Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination
Author response: Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract In Spring 2021, the hi…
View article: Impact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: a multi-model study
Impact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: a multi-model study Open
Summary Background SARS-CoV-2 vaccination of persons aged 12 years and older has reduced disease burden in the United States. The COVID-19 Scenario Modeling Hub convened multiple modeling teams in September 2021 to project the impact of ex…
View article: Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–July, 2021
Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–July, 2021 Open
As of March 2021, three COVID-19 vaccines had been authorized by the U.S. Food and Drug Administration (FDA) for use in the United States. Each has substantial efficacy in preventing COVID-19. However, as efficacy from trials was <100% for…
View article: Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination
Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination Open
In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed vaccination uptake, this novel variant was expected t…
View article: Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–July, 2021
Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–July, 2021 Open
As of March 2021, three COVID-19 vaccines had been authorized by the U.S. Food and Drug Administration (FDA) for use in the United States. Each has substantial efficacy in preventing COVID-19. However, as efficacy from trials was <100% for…
View article: Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination
Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination Open
Summary What is already known about this topic? The highly transmissible SARS-CoV-2 Delta variant has begun to cause increases in cases, hospitalizations, and deaths in parts of the United States. With slowed vaccination uptake, this novel…
View article: Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–April, 2021
Estimating the number of symptomatic SARS-CoV-2 infections among vaccinated individuals in the United States—January–April, 2021 Open
As of March 2021, three COVID-19 vaccines have been authorized by the U.S. Food and Drug Administration (FDA) for use in the United States. Each has substantial efficacy in preventing COVID-19. However, as efficacy from trials was <100% fo…
View article: Modeling of Future COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Rates and Nonpharmaceutical Intervention Scenarios — United States, April–September 2021
Modeling of Future COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Rates and Nonpharmaceutical Intervention Scenarios — United States, April–September 2021 Open
After a period of rapidly declining U.S. COVID-19 incidence during January-March 2021, increases occurred in several jurisdictions (1,2) despite the rapid rollout of a large-scale vaccination program. This increase coincided with the sprea…
View article: Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016
Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016 Open
Emerging epidemics are challenging to track. Only a subset of cases is recognized and reported, as seen with the Zika virus (ZIKV) epidemic where large proportions of infection were asymptomatic. However, multiple imperfect indicators of i…
View article: Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016
Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016 Open
Emerging epidemics are challenging to track. Only a subset of cases is recognized and reported, as seen with the Zika virus (ZIKV) epidemic where large proportions of infection were asymptomatic. However, multiple imperfect indicators of i…
View article: Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020
Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020 Open
Older adults are susceptible to severe coronavirus disease 2019 (COVID-19) outcomes as a consequence of their age and, in some cases, underlying health conditions (1). A COVID-19 outbreak in a long-term care skilled nursing facility (SNF) …