Jessica N. Wilson
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View article: Pseudocannabinoid H4CBD enhances lipid catabolism to reduce visceral adiposity and large adipocyte size in advanced metabolic syndrome
Pseudocannabinoid H4CBD enhances lipid catabolism to reduce visceral adiposity and large adipocyte size in advanced metabolic syndrome Open
Background Metabolic Syndrome (MetS) is a precursor for cardiovascular disease (CVD) and type 2 diabetes (T2D) and has a prevalence of 55% among people ≥ 60 years of age in the US. Cannabidiol (CBD) use has grown more popular in the last t…
View article: Sex and <i>APOE</i> genotype influence respiratory function under hypoxic and hypoxic-hypercapnic conditions
Sex and <i>APOE</i> genotype influence respiratory function under hypoxic and hypoxic-hypercapnic conditions Open
This study is the first to use whole body plethysmography (WBP) to measure the impact of APOE alleles on breathing under normoxia and during adverse respiratory challenges in a targeted replacement Alzheimer’s model. Both sex and genotype …
View article: Safety and efficacy of dynamic catheter-directed cerebral digital subtraction angiography for diagnosis of bowhunter syndrome spectrum disorders: A systematic review of the literature
Safety and efficacy of dynamic catheter-directed cerebral digital subtraction angiography for diagnosis of bowhunter syndrome spectrum disorders: A systematic review of the literature Open
Introduction Dynamic catheter-directed cerebral digital subtraction angiography (dcDSA) is the gold standard for diagnosing dynamic vascular occlusion syndromes such as bowhunter syndrome (BHS). Nonetheless, concerns about its safety exist…
View article: Fighter Pilot Syndrome: A Bow Hunter Syndrome Variant Identified With Dynamic Cerebral Angiography
Fighter Pilot Syndrome: A Bow Hunter Syndrome Variant Identified With Dynamic Cerebral Angiography Open
Background Dynamic compression of extracranial arteries in the cervicocerebral circulation is a rare phenomenon of ischemic stroke. Methods Retrospective chart review. Results Here, we present a young fighter pilot who presented with recur…
View article: Pseudocannabinoid H4CBD improves glucose response during advanced metabolic syndrome in OLETF rats independent of increase in insulin signaling proteins
Pseudocannabinoid H4CBD improves glucose response during advanced metabolic syndrome in OLETF rats independent of increase in insulin signaling proteins Open
Cannabis product use has grown in the last two decades despite the lack of research on Cannabidiol (CBD)-mediated effects on metabolism. Here, we provide seminal data on CBD effects during age-associated metabolic dysfunction. We gave 41-w…
View article: Targeting the Microbiome to Improve Gut Health and Breathing Function After Spinal Cord Injury
Targeting the Microbiome to Improve Gut Health and Breathing Function After Spinal Cord Injury Open
Spinal cord injury (SCI) is a devastating condition characterized by impaired motor and sensory function, as well as internal organ pathology and dysfunction. This internal organ dysfunction, particularly gastrointestinal (GI) complication…
View article: Sex and<i>APOE</i>Genotype Influence Respiratory Function Under Hypoxic and Hypoxic-Hypercapnic Conditions
Sex and<i>APOE</i>Genotype Influence Respiratory Function Under Hypoxic and Hypoxic-Hypercapnic Conditions Open
The apolipoprotein (APOE) gene has been studied due to its influence on Alzheimer’s disease (AD) development and work in an APOE mouse model recently demonstrated impaired respiratory motor plasticity following spinal cord injury (SCI). In…
View article: Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii
Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii Open
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii , which causes lethal secondary infections in chronically infected mice. Here we…
View article: <i>Nfkbid</i>is required for immunity and antibody responses to<i>Toxoplasma gondii</i>
<i>Nfkbid</i>is required for immunity and antibody responses to<i>Toxoplasma gondii</i> Open
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii , which causes lethal secondary infections in chronically infected mice. Here we…
View article: More Is Better: Resistant and Susceptible Mouse Model Reveals Toxoplasma gondii Glycophosphatidylinositol Anchor to be a Common Natural Antibody Epitope
More Is Better: Resistant and Susceptible Mouse Model Reveals Toxoplasma gondii Glycophosphatidylinositol Anchor to be a Common Natural Antibody Epitope Open
Parasitic disease is a global health burden. Current and historical efforts to eradicate parasitic disease rely heavily on vector control and mass drug administration campaigns rather than vaccine induced immunity due in large part to effe…