James Lau
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View article: Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding
Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding Open
This guideline has been formally endorsed by leading international endoscopy societies: the American Society for Gastrointestinal Endoscopy, the European Society of Gastrointestinal Endoscopy, the Sociedad Interamericana de Endoscopía Dige…
View article: Effects of amoxicillin dosage on cure rate, gut microbiota, and antibiotic resistome in vonoprazan and amoxicillin dual therapy for Helicobacter pylori: a multicentre, open-label, non-inferiority randomised controlled trial
Effects of amoxicillin dosage on cure rate, gut microbiota, and antibiotic resistome in vonoprazan and amoxicillin dual therapy for Helicobacter pylori: a multicentre, open-label, non-inferiority randomised controlled trial Open
National Natural Science Foundation of China, Project for Academic and Technical Leaders of Major Disciplines in Jiangxi Province, and Key Research and Development Program of Jiangxi Province.
View article: CMV Reactivation Pre and Post Letermovir Prophylaxis, a Single Centre Review of Clinical Outcomes and Resource Utilization
CMV Reactivation Pre and Post Letermovir Prophylaxis, a Single Centre Review of Clinical Outcomes and Resource Utilization Open
Introduction Prospective, randomized trials have demonstrated reduction in the incidence of clinically significant CMV infections (csCMVi) with use of letermovir prophylaxis (LP) in allogeneic hematopoietic stem cell transplant (alloHSCT).…
View article: Efficacy and safety of a single-use cholangioscope for percutaneous transhepatic cholangioscopy
Efficacy and safety of a single-use cholangioscope for percutaneous transhepatic cholangioscopy Open
Background and study aims Percutaneous transhepatic cholangioscopy (PTCS) is a management option for patients in whom peroral cholangioscopy or endoscopic retrograde cholangiopancreatography (ERCP) fail. We conducted a case series on the e…
View article: Metronidazole-induced neurotoxicity
Metronidazole-induced neurotoxicity Open
Rationale: Nervous system toxicity is a rare complication of metronidazole. Prompt identification of metronidazole toxicity combined with a comprehensive physical rehabilitation program is essential to maximizing the patient’s functional o…
View article: Acute gastrointestinal bleeding: proposed study outcomes for new randomised controlled trials
Acute gastrointestinal bleeding: proposed study outcomes for new randomised controlled trials Open
Summary Background Acute gastrointestinal bleeding (GIB) remains a common cause of hospitalisation. However, interpretation and comparisons of published studies in GIB have been hampered by disparate study methodology. Aims To make recomme…
View article: Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021
Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021 Open
MAIN RECOMMENDATIONS 1 ESGE recommends in patients with acute upper gastrointestinal hemorrhage (UGIH) the use of the Glasgow–Blatchford Score (GBS) for pre-endoscopy risk stratification. Patients with GBS ≤ 1 are at very low risk of reble…
View article: Future of Work in an Age of Automation, Artificial Intelligence and Technology
Future of Work in an Age of Automation, Artificial Intelligence and Technology Open
I wrote this article to create greater awareness of the interconnection between work and technology and as a small contribution towards the wider, collective efforts for a human-centric future with inclusive and shared prosperity.
View article: 2 Essential Personality Traits In-House Counsel Need to Thrive and Succeed in an Age of AI & VUCA World
2 Essential Personality Traits In-House Counsel Need to Thrive and Succeed in an Age of AI & VUCA World Open
I wrote this article to set out my own personal perspective on the 2 essential personality traits which in-house counsels need in order to thrive and succeed in an age of AI and in a Volatile, Uncertain, Complex and Ambiguous (VUCA) world.
View article: Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group
Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group Open
Preendoscopic management: The group suggests using a Glasgow Blatchford score of 1 or less to identify patients at very low risk for rebleeding, who may not require hospitalization. In patients without cardiovascular disease, the suggested…
View article: Artificial Intelligence, Machine Learning, Technology and the Legal Profession-Perspective of an Asian Chief Legal Officer
Artificial Intelligence, Machine Learning, Technology and the Legal Profession-Perspective of an Asian Chief Legal Officer Open
I wrote this article to engender debate and discussion by the wider legal community to formulate a common shared vision on how the legal profession can and should harness and use artificial intelligence, machine learning and technology abo…
View article: How In-House Counsels in Asia Can Thrive and Succeed in an Age of Ai and in a VUCA World
How In-House Counsels in Asia Can Thrive and Succeed in an Age of Ai and in a VUCA World Open
I wrote this article to share my own personal perspective on how in-house counsels in Asia can thrive and succeed in an age of artificial intelligence (“AI”) and in a volatile, uncertain, complex and ambiguous (“VUCA”) world.
View article: Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018
Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018 Open
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the ’gold standard' of management, treatment of these patients can be considere…
View article: In-situ medical simulation for pre-implementation testing of clinical service in a regional hospital in Hong Kong
In-situ medical simulation for pre-implementation testing of clinical service in a regional hospital in Hong Kong Open
The implementation of a new clinical service is associated with anxiety and challenges that may prevent smooth and safe execution of the service. Unexpected issues may not be apparent until the actual clinical service commences. We present…
View article: Learning to Collaborate & Share Cyber Threat Intelligence in Fight Against Social Engineering Fraud Facilitated by Human Error
Learning to Collaborate & Share Cyber Threat Intelligence in Fight Against Social Engineering Fraud Facilitated by Human Error Open
This article is intended for in-house counsel to help create greater awareness of social engineering fraud, the need for collaboration and sharing cyber-security threat intelligence and to help cascade common sensical good hygiene practice…
View article: Comparison of outcomes in patients at high risk for recurrent gastroesophageal variceal bleeding treated by endoscopic ultrasound-guided cyanoacrylate injection for secondary prophylaxis or conventional endoscopic cyanoacrylate injection for index bleeding alone
Comparison of outcomes in patients at high risk for recurrent gastroesophageal variceal bleeding treated by endoscopic ultrasound-guided cyanoacrylate injection for secondary prophylaxis or conventional endoscopic cyanoacrylate injection for index bleeding alone Open
BACKGROUND AND OBJECTIVES: Patients with hepatocellular carcinoma (HCC) or other malignancies with portal vein thrombosis (PVT) are at high risk for recurrent variceal bleeding. Recent evidence suggested that secondary prophylaxis (SP) for…
View article: Efficacy and safety of novel digital single-operator peroral cholangioscopy-guided laser lithotripsy for complicated biliary stones
Efficacy and safety of novel digital single-operator peroral cholangioscopy-guided laser lithotripsy for complicated biliary stones Open
Background/study aims Laser lithotripsy can effectively fragment complicated biliary stones, but current cholangioscopes are limited by fragility, restricted mobility or moderate visual resolution. The efficacy and safety of a new digital …