Jessy Abraham
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View article: Leveraging circulating DNase I activity to detect silent coronary artery disease among hypertensive diabetes individuals
Leveraging circulating DNase I activity to detect silent coronary artery disease among hypertensive diabetes individuals Open
Our observation suggests that the progression of cardiac disease among hypertensive patients with diabetes is associated with elevated DNase I activity that maintains optimal cfDNA levels, thereby reducing its inflammatory potential and wo…
View article: Prevalence, Phenotypes, and Comorbidities of Polycystic Ovary Syndrome Among Indian Women
Prevalence, Phenotypes, and Comorbidities of Polycystic Ovary Syndrome Among Indian Women Open
Importance The prevalence of polycystic ovary syndrome (PCOS) varies across the globe. Indian studies on PCOS are limited by poor design, small sizes, regional representations, and varying methods. Objectives To estimate the nationwide pre…
View article: " Meditation: Quite the mind and the soul will speak" (Preprint)
" Meditation: Quite the mind and the soul will speak" (Preprint) Open
BACKGROUND Meditation is often defined as thinking continuously about one object of thought. We often get stuck on this definition, however, and lose the real purpose of meditation. Meditation must reveal the true nature of that object up…
View article: Association of p53 codon 72 polymorphism with weight and metabolic diseases in a Central Indian population
Association of p53 codon 72 polymorphism with weight and metabolic diseases in a Central Indian population Open
Background Metabolic dysregulation leading to diabetes is a major public health concern in India. While evidence has pointed to a role for genetic factors, there is still limited knowledge regarding the specific variants that play a part i…
View article: A COMPARATIVE STUDY ON THE PREVALENCE AND RISK OF CARDIOVASCULAR DISEASE AMONG MALE AND FEMALE ADULTS IN A SELECTED COMMUNITY AT MULAKKULAM PANCHAYATH (Preprint)
A COMPARATIVE STUDY ON THE PREVALENCE AND RISK OF CARDIOVASCULAR DISEASE AMONG MALE AND FEMALE ADULTS IN A SELECTED COMMUNITY AT MULAKKULAM PANCHAYATH (Preprint) Open
BACKGROUND A study conducted to assess the prevalence and risk of cardiovascular disease among male and female adults in a selected community at Mulakkulam panchayath OBJECTIVE The objectives of the study were to assess the prevalence a…
View article: Plasma mitochondrial <scp>DNA</scp> is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus
Plasma mitochondrial <span>DNA</span> is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus Open
Background We evaluated whether an abundance of first‐trimester plasma mitochondrial DNA (mtDNA) fragments could predict the risk for the development of gestational diabetes mellitus (GDM) by the late second or early third trimester. Metho…
View article: Normative range of various serum hormonal parameters among Indian women of reproductive age: ICMR-PCOS task force study outcome
Normative range of various serum hormonal parameters among Indian women of reproductive age: ICMR-PCOS task force study outcome Open
The study was financially supported by the grant-in-aid from ICMR vide file No:5/7/13337/2015-RBMH.
View article: Effect of the Angiotensin-Converting Enzyme (ACE) (I/D) Polymorphism in COVID-19 Patients and Their Healthy Contacts
Effect of the Angiotensin-Converting Enzyme (ACE) (I/D) Polymorphism in COVID-19 Patients and Their Healthy Contacts Open
Introduction The quest to understand the pathophysiology behind the deleterious effects of the coronavirus disease 2019 (COVID-19) outbreak took a turn when involvement of the angiotensin converting enzyme (ACE) receptors in different orga…
View article: Data from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
Data from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias Open
Purpose: It has been reported that approximately a million women are diagnosed with benign breast lesions that include ductal hyperplasias per year in the United States. Recent studies that followed women with benign lesions have establish…
View article: Data from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
Data from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias Open
Purpose: It has been reported that approximately a million women are diagnosed with benign breast lesions that include ductal hyperplasias per year in the United States. Recent studies that followed women with benign lesions have establish…
View article: Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias Open
Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
View article: Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias Open
Supplementary Table S1 from Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias
View article: A pilot study to evaluate the changes in venous blood gas parameters and hypoxia biomarkers in health care workers using different kinds of masks
A pilot study to evaluate the changes in venous blood gas parameters and hypoxia biomarkers in health care workers using different kinds of masks Open
Background: The study is aimed to investigate the metabolic alterations and changes in biochemical parameters associated with extended mask. Methods: It was a prospective comparative study conducted on 129 participants comprised of 37 heal…
View article: Impact of "Yoga Based Lifestyle Interventions" and its Implications on Health and Disease
Impact of "Yoga Based Lifestyle Interventions" and its Implications on Health and Disease Open
Yoga and meditation address mind and body, affecting many molecular processes like metabolism, epigenetic, oxidative processes, and subjective well-being. In this review, we have compiled the results of various clinical trials that have lo…
View article: Liquid biopsy - emergence of a new era in personalized cancer care
Liquid biopsy - emergence of a new era in personalized cancer care Open
The most successful treatment for cancer involves identifying druggable, biological markers for targeted therapy. In the clinical setting, surgical removal of tumors is the only procedure for identifying such targetable molecules. Shed fro…
View article: Implication of asana, pranayama and meditation on telomere stability
Implication of asana, pranayama and meditation on telomere stability Open
Telomeres, the repetitive sequences that protect the ends of chromosomes, help to maintain genomic integrity and are of key importance to human health. Telomeres progressively shorten throughout life and a number of studies have shown shor…
View article: Anatomical correlation of core muscle activation in different yogic postures
Anatomical correlation of core muscle activation in different yogic postures Open
Faulty postures due to sedentary lifestyle cause weakening of core muscles which contributes to increased incidence of musculoskeletal disorders (MSDs). Although a few research studies have quantified the core muscle activity in various yo…
View article: Prediabetes and Undiagnosed Diabetes Mellitus: The Hidden Danger
Prediabetes and Undiagnosed Diabetes Mellitus: The Hidden Danger Open
Introduction Diabetes is considered as a major challenge to the public health system in India. Recent articles clearly mention that the hidden danger in the form of prediabetes and undiagnosed diabetes is greatly adding to the burden silen…