Jing You
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View article: DNA Methylation of <i>FAM50B</i> / <i>PTCHD3</i> Mediates the Relationships between Low Blood Lead Exposure and Neurobehavioral Development of 0–3 Aged Infants: A Prospective Birth Cohort Study in Southern China
DNA Methylation of <i>FAM50B</i> / <i>PTCHD3</i> Mediates the Relationships between Low Blood Lead Exposure and Neurobehavioral Development of 0–3 Aged Infants: A Prospective Birth Cohort Study in Southern China Open
View article: A life cycle risk assessment of nanopesticides in freshwater
A life cycle risk assessment of nanopesticides in freshwater Open
View article: Life cycle environmental and economic impacts of various energy storage systems: eco-efficiency analysis and potential for sustainable deployments
Life cycle environmental and economic impacts of various energy storage systems: eco-efficiency analysis and potential for sustainable deployments Open
The deployment of energy storage systems (ESS) plays a pivotal role in accelerating the global transition to renewable energy sources. Comprehending the life cycle environmental and economic impacts, as well as the necessary conditions and…
View article: Elevation Shapes Thermal Breadth and Climate Sensitivity in Moltrecht's Treefrog Tadpoles
Elevation Shapes Thermal Breadth and Climate Sensitivity in Moltrecht's Treefrog Tadpoles Open
View article: Polycyclic Nitroaromatic Compounds in Water-Soluble Humic-Like Substances are the Key Components to Induce Apoptosis in Pm2.5
Polycyclic Nitroaromatic Compounds in Water-Soluble Humic-Like Substances are the Key Components to Induce Apoptosis in Pm2.5 Open
View article: Development of 420 MPa Grade High-Performance Steel Plate for Wind Power
Development of 420 MPa Grade High-Performance Steel Plate for Wind Power Open
Wind power, an environmentally friendly renewable energy source, has been widely adopted globally. The advancement in large-scale wind power equipment design technology has led to increased demands for steel plates with high strength, low-…
View article: Simulating and investigating various dynamic aspects of the $\rm{H}_2\rm{O}$-related hydrogen bond model
Simulating and investigating various dynamic aspects of the $\rm{H}_2\rm{O}$-related hydrogen bond model Open
A basic model of hydrogen bonds related to $\rm{H}_2\rm{O}$, which is adapted from the Jaynes--Cummings model, is suggested, and its different dynamic features are studied theoretically. In this model, the making and breaking of hydrogen b…
View article: Sensitivity Variations in Developmental Toxicity of Imidacloprid to Zebrafish Embryos at Different Neurodevelopmental Stages
Sensitivity Variations in Developmental Toxicity of Imidacloprid to Zebrafish Embryos at Different Neurodevelopmental Stages Open
Neonicotinoids are ubiquitous in global surface waters and pose a significant risk to aquatic organisms. However, information is lacking on the variations in sensitivity of organisms at different developmental stages to the neurotoxic neon…
View article: Evidence from In Situ Bioassays and Suspect Analysis Revealed the Region-Specific Aquatic Risk across Socioeconomic Gradients in China
Evidence from In Situ Bioassays and Suspect Analysis Revealed the Region-Specific Aquatic Risk across Socioeconomic Gradients in China Open
Various contaminants are present in aquatic environment and pose potential threats to pelagic and benthic organisms, calling for effective risk assessment. Traditional risk assessments based on target analysis are useful when the principal…
View article: Sense of alienation, security, and life satisfaction among undergraduate: a cross-sectional study from China
Sense of alienation, security, and life satisfaction among undergraduate: a cross-sectional study from China Open
Objective To explore the factors influencing alienation among college students and to explore the relationship between alienation and feelings of security and life satisfaction. Methods 2,932 students in university were surveyed by using w…
View article: Prioritizing Organic Pollutants for Shale Gas Exploitation: Life Cycle Environmental Risk Assessments in China and the US
Prioritizing Organic Pollutants for Shale Gas Exploitation: Life Cycle Environmental Risk Assessments in China and the US Open
Environmental impacts associated with shale gas exploitation have been historically underestimated due to neglecting to account for the production or the release of end-of-pipe organic pollutants. Here, we assessed the environmental impact…
View article: How are cobalt, selenium, and copper related to diabetes risk? A cohort study in rural areas of Xinxiang city
How are cobalt, selenium, and copper related to diabetes risk? A cohort study in rural areas of Xinxiang city Open
Background: The long-term associationsbetween serum cobalt (Co), copper (Cu) and selenium (Se) intake and the risk of type 2 diabetes mellitus (T2DM) are unclear. This study aimed to explore the relationship between serum Co, Cu, and Se in…
View article: [Mutational Signatures Analysis of Micropapillary Components and Exploration of ZNF469 Gene in Early-stage Lung Adenocarcinoma with Ground-glass Opacities].
[Mutational Signatures Analysis of Micropapillary Components and Exploration of ZNF469 Gene in Early-stage Lung Adenocarcinoma with Ground-glass Opacities]. Open
The study has unveiled distinctive mutational signatures in the MPP components of early-stage invasive LUAD in the Asian population. Furthermore, we have identified that the elevated expression of mutated ZNF469 impacts the prognosis and i…
View article: [Liposome nanoparticles for targeted delivery of parthenolide induce colorectal cancer necroptosis to ameliorate tumor-infiltrating T cell exhaustion in mice].
[Liposome nanoparticles for targeted delivery of parthenolide induce colorectal cancer necroptosis to ameliorate tumor-infiltrating T cell exhaustion in mice]. Open
Parthenolide induces necroptosis in CRC and increases infiltrating CD8+ T cells to ameliorate CD8+ T cell exhaustion in the tumor. Liposome nanoparticles for targeted delivery of parthenolide produce stronger, anti-tu…
View article: Correction: Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing
Correction: Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing Open
View article: Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing
Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing Open
View article: Life cycle thinking supports 21st-century new pollutant and chemical management
Life cycle thinking supports 21st-century new pollutant and chemical management Open
Millions of chemicals are on the market; many of these pose potential human health and ecological risks that are insufficiently addressed and may be falling through the cracks of current assessment and regulatory systems. New pollutants, a…
View article: A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell
A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell Open
View article: Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway
Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway Open
Background Sepsis is a life-threatening organ dysfunction syndrome resulted from severe infection with high morbidity and mortality. Cluster of differentiation 38 (CD38) is a multifunctional type II transmembrane glycoprotein widely expres…
View article: [Correlation between Immune Microenvironment Features and EGFR Mutation Status
in Lung Adenocarcinoma].
[Correlation between Immune Microenvironment Features and EGFR Mutation Status
in Lung Adenocarcinoma]. Open
EGFR-mutated lung adenocarcinoma had a unique "non-inflammatory" tumor microenvironment with low infiltration of immune cells, and there was also heterogeneity in the tumor microenvironment among the tumors with different mutation subtypes…
View article: On the Formation and Nature of Internal Migration Policies in China: Patterns and Determinants of the Household Registration Reform in 2014
On the Formation and Nature of Internal Migration Policies in China: Patterns and Determinants of the Household Registration Reform in 2014 Open
View article: The Operation Mode of Agricultural Supply Chain Finance Using Blockchain
The Operation Mode of Agricultural Supply Chain Finance Using Blockchain Open
With the rapid development of agriculture, modern agriculture has achieved remarkable results. Agriculture is the foundation of China’s national economy, and the Party Central Committee has always insisted on solving the “three rural issue…
View article: Neuroprotective effects of resveratrol against cerebral ischemia/reperfusion injury through anti-oxidant and anti-inflammatory mechanisms：A Systematic Review and Meta-Analysis in Rodents
Neuroprotective effects of resveratrol against cerebral ischemia/reperfusion injury through anti-oxidant and anti-inflammatory mechanisms：A Systematic Review and Meta-Analysis in Rodents Open
Review question / Objective: To systematically evaluate the effects of resveratrol in the treatment of animal models of cerebral I/R injury , and to preliminarily explore the mechanisms, so as to provide a basic evidence-based reference fo…
View article: Sustainable development index of shale gas exploitation in China, the UK, and the US
Sustainable development index of shale gas exploitation in China, the UK, and the US Open
View article: Culture Effects on the Chinese Version Boston Naming Test Performance and the Normative Data in the Native Chinese-Speaking Elders in Mainland China
Culture Effects on the Chinese Version Boston Naming Test Performance and the Normative Data in the Native Chinese-Speaking Elders in Mainland China Open
Background The Chinese version of Boston Naming Test (BNT-C) is administered in China widely. However, the neuropsychological parameter of BNT-C in native Chinese-speaking elders in mainland China has not been explored systematically. The …
View article: Characterization of Peanut Protein Hydrolysate and Structural Identification of Umami-Enhancing Peptides
Characterization of Peanut Protein Hydrolysate and Structural Identification of Umami-Enhancing Peptides Open
Umami peptides are naturally found in various foods and have been proven to be essential components contributing to food taste. Defatted peanut powder hydrolysate produced by a multiprotease (Flavorzyme, Alcalase, and Protamex) was found t…
View article: Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway
Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway Open
Background: Sepsis is a life-threatening organ dysfunction syndrome resulted from severe infection with high morbidity and mortality. Cluster of differentiation 38 (CD38) is a multifunctional type Ⅱ transmembrane glycoprotein widely expres…
View article: Bibliometric Visualization Analysis of Microbiome-Gut-Brain Axis from 2004 to 2020
Bibliometric Visualization Analysis of Microbiome-Gut-Brain Axis from 2004 to 2020 Open
BACKGROUND The microbiome-gut-brain axis (MGBA) is the biochemical signal of the digestive tract and central nervous system. MGBA disorders have been increasingly involved in the pathological process of neurological diseases. This study ai…
View article: Protective effect of phillyrin against cerebral ischemia/reperfusion injury in rats and oxidative stress-induced cell apoptosis and autophagy in neurons
Protective effect of phillyrin against cerebral ischemia/reperfusion injury in rats and oxidative stress-induced cell apoptosis and autophagy in neurons Open
This study explored the role and potential molecular mechanism of phillyrin in cerebral ischemia/reperfusion (I/R) injury. The rat middle cerebral artery occlusion (MCAO)/R model was constructed, and cerebral infarction volume, brain water…
View article: Reduced Concentrations and Toxicity of Sediment-Associated Pesticides from Vegetable Planting Field to Surrounding Waterways: Impacts of Chemical Properties and Intrinsic Toxicity
Reduced Concentrations and Toxicity of Sediment-Associated Pesticides from Vegetable Planting Field to Surrounding Waterways: Impacts of Chemical Properties and Intrinsic Toxicity Open