Jian Chen
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View article: A High Magnifications Histopathology Image Dataset for Oral Squamous Cell Carcinoma Diagnosis and Prognosis
A High Magnifications Histopathology Image Dataset for Oral Squamous Cell Carcinoma Diagnosis and Prognosis Open
Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive malignancy where deep learning-based computer-aided diagnosis and prognosis can enhance clinical assessments.However, existing publicly available OSCC datasets often suffer …
View article: An Innovative Stepwise C‐Means Clustering Approach for Classification of Adolescent Idiopathic Scoliosis
An Innovative Stepwise C‐Means Clustering Approach for Classification of Adolescent Idiopathic Scoliosis Open
Objective Existing 3D classification systems for scoliosis primarily guide surgical treatment, with limited application in conservative management. This study aims to establish a preliminary 3D classification system for moderate adolescent…
View article: Total hip arthroplasty, through the direct anterior approach, for a femoral neck fracture of ipsilateral transfemoral amputee: a case report
Total hip arthroplasty, through the direct anterior approach, for a femoral neck fracture of ipsilateral transfemoral amputee: a case report Open
Objective Femoral neck fractures in transfemoral amputees are rare, and their management remains controversial, particularly in individuals with short residual limb lengths. Traditional approaches to total hip arthroplasty (THA), such as t…
View article: The SG‐Climbot: An Adaptable, Efficient, Inspection and Repair Robot for Steam Generator Heat Transfer Tube Sheet
The SG‐Climbot: An Adaptable, Efficient, Inspection and Repair Robot for Steam Generator Heat Transfer Tube Sheet Open
The steam generator plays a crucial role as a safety component and protective barrier in nuclear power plants. Regular inspection and repair of heat transfer tubes, which operate in high‐temperature, high‐pressure, corrosive, and abrasive …
View article: Tumor complete response and pyogenic liver abscess secondary to concurrent microwave ablation plus atezolizumab and bevacizumab in liver cancer: a case report
Tumor complete response and pyogenic liver abscess secondary to concurrent microwave ablation plus atezolizumab and bevacizumab in liver cancer: a case report Open
In patients undergoing atezolizumab and bevacizumab, the potential risk of PLA versus the antitumor benefit of microwave ablation requires to be assessed. The use of multiple courses of antibiotics over a prolonged period did not appear to…
View article: [Treatment of cervical ossification of posterior longitudinal ligament with titanium alloy trabecular bone three-dimensional printed artificial vertebral body].
[Treatment of cervical ossification of posterior longitudinal ligament with titanium alloy trabecular bone three-dimensional printed artificial vertebral body]. Open
Compared to traditional titanium cages, the use of titanium alloy trabecular bone 3D-printed artificial vertebral bodies for treating cervical OPLL results in shorter operative time, fewer postoperative complications, and lower implant sub…
View article: What lies beneath: White matter microstructure in pediatric myalgic encephalomyelitis/chronic fatigue syndrome using diffusion <scp>MRI</scp>
What lies beneath: White matter microstructure in pediatric myalgic encephalomyelitis/chronic fatigue syndrome using diffusion <span>MRI</span> Open
Recent studies in adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggest that changes in brain white matter microstructural organization may correlate with core ME/CFS symptoms, and represent a potential biomarker …
View article: Long-term outcomes and potential mechanisms of offspring exposed to intrauterine hyperglycemia
Long-term outcomes and potential mechanisms of offspring exposed to intrauterine hyperglycemia Open
Diabetes mellitus during pregnancy, which can be classified into pregestational diabetes and gestational diabetes, has become much more prevalent worldwide. Maternal diabetes fosters an intrauterine abnormal environment for fetus, which no…
View article: Retroperitoneal parasitic fetus: A case report
Retroperitoneal parasitic fetus: A case report Open
A laparotomy was performed at 26 d of age with excision of the retroperitoneal cystic tumor, which measured about 10 cm in diameter. According to the result of imaging and histological test, FIF was confirmed.
View article: Preterm neonatal mortality in China during 2009–2018: A retrospective study
Preterm neonatal mortality in China during 2009–2018: A retrospective study Open
In this retrospective analysis, we aimed to analyze the epidemic characteristics of neonatal mortality due to preterm birth at 28–36 weeks gestation in different regions from 2009 to 2018. Data were obtained from China’s Under-5 Child Mort…
View article: The Correlation of MDM4(rs4245739, rs1563828, rs11801299, rs10900598 and rs1380576) polymorphisms with cancer susceptibility：A meta-analysis
The Correlation of MDM4(rs4245739, rs1563828, rs11801299, rs10900598 and rs1380576) polymorphisms with cancer susceptibility：A meta-analysis Open
Review question / Objective: The connection between MDM4 polymorphisms and tumor risk has been investigated by several studies and yielded different results.Therefore, we are going to perform a meta-analysis to assess synthetically the ass…
View article: Subsequent placenta accreta after previous mifepristone-induced abortion: A case report
Subsequent placenta accreta after previous mifepristone-induced abortion: A case report Open
BACKGROUND: Mifepristone-induced abortion (MIA) has been used worldwide to terminate pregnancies. However, the association between placenta accrete (PA) and MIA has seldom been reported. CASE SUMMARY: A 26-year-old pregnant woman presented…
View article: Contrast-Enhanced Intraoperative Ultrasonography with Kupffer Phase May Change Treatment Strategy of Metastatic Liver Tumors – A Single-Centre Prospective Study
Contrast-Enhanced Intraoperative Ultrasonography with Kupffer Phase May Change Treatment Strategy of Metastatic Liver Tumors – A Single-Centre Prospective Study Open
CE-IOUS may play a similar or even better role than other radiological methods in diagnosing liver metastasis. The CE-IOUS using Sonazoid demonstrated a high sensitivity and specificity for finding occult metastases intraoperatively and ch…
View article: Efficacy and safety of traditional Chinese medicine rehabilitation program in the treatment of knee osteoarthritis: a randomized controlled trial protocol
Efficacy and safety of traditional Chinese medicine rehabilitation program in the treatment of knee osteoarthritis: a randomized controlled trial protocol Open
The results will provide high-quality guidance for the current clinical treatment of KOA, and provide patients with more options for symptom relief. The findings from this study may provide updated evidence concerning the efficacy and safe…
View article: Prevalence and Risk Factors for Spasticity After Stroke: A Systematic Review and Meta-Analysis
Prevalence and Risk Factors for Spasticity After Stroke: A Systematic Review and Meta-Analysis Open
Background: Spasticity is a common sequela of stroke. The incidence of poststroke spasticity (PSS) has not been systematically reviewed in recent years, and some risk factors remain debated. This systematic review and meta-analysis was con…
View article: Risk and Predictive Factors for Proximal Junctional Kyphosis in Patients Treated by Lenke Type 5 Adolescent Idiopathic Scoliosis Correction
Risk and Predictive Factors for Proximal Junctional Kyphosis in Patients Treated by Lenke Type 5 Adolescent Idiopathic Scoliosis Correction Open
The results of the present study have shown that the postoperative PJA and postoperative TK can be used to effectively predict for the occurrence of PJK in patients with Lenke type 5 AIS after corrective surgery, with a threshold of 9.45° …
View article: The correlation of duration of cervical flexion per day with neck disability index scores in office workers: a cross sectional study
The correlation of duration of cervical flexion per day with neck disability index scores in office workers: a cross sectional study Open
Background: An increasing number of office workers complain of neck pain after extended smart phone use. We conducted this study to examine the correlation between the duration of cervical flexion per day (DCF) during smart phone use and n…
View article: Fiber Type-Specific Morphological and Cellular Changes of Paraspinal Muscles in Patients with Severe Adolescent Idiopathic Scoliosis
Fiber Type-Specific Morphological and Cellular Changes of Paraspinal Muscles in Patients with Severe Adolescent Idiopathic Scoliosis Open
BACKGROUND Paraspinal muscle (PSM) has been suggested to have a role in adolescent idiopathic scoliosis (AIS). Few studies have investigated the fiber type-specific changes of PSM in detail. MATERIAL AND METHODS Bilateral multifidus muscle…
View article: A Retrospective Study of Surgical Correction for Spinal Deformity with and without Osteotomy to Compare Outcome Using Intraoperative Neurophysiological Monitoring with Evoked Potentials
A Retrospective Study of Surgical Correction for Spinal Deformity with and without Osteotomy to Compare Outcome Using Intraoperative Neurophysiological Monitoring with Evoked Potentials Open
BACKGROUND This study aimed to evaluate the effects of different combined evoked potentials monitoring modes for non-osteotomy and osteotomy surgery of spinal deformity, and to select individualized modes for various surgeries. MATERIAL AN…
View article: Selective intra-arterial brain cooling improves long-term outcomes in a non-human primate model of embolic stroke: Efficacy depending on reperfusion status
Selective intra-arterial brain cooling improves long-term outcomes in a non-human primate model of embolic stroke: Efficacy depending on reperfusion status Open
Nearly all stroke neuroprotection modalities, including selective intra-arterial cooling (SI-AC), have failed to be translated from bench to bed side. Potentially overlooked reasons may be biological gaps, inadequate attention to reperfusi…
View article: White matter extension of the Melbourne Children's Regional Infant Brain atlas: M‐CRIB‐WM
White matter extension of the Melbourne Children's Regional Infant Brain atlas: M‐CRIB‐WM Open
Brain atlases providing standardised identification of neonatal brain regions are key in investigating neurological disorders of early childhood. Our previously developed Melbourne Children's Regional Infant Brain (M‐CRIB) and M‐CRIB 2.0 n…
View article: Diagnostic issue on spontaneous osteonecrosis of medial tibial plateau
Diagnostic issue on spontaneous osteonecrosis of medial tibial plateau Open
To the Editor: I read with great interest the recent report of Yang et al[1], “Clinical Characteristics and Treatment of Spontaneous Osteonecrosis of Medial Tibial Plateau: A retrospective case study” (published on November 5, 2018, Chin M…
View article: Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China: a descriptive analysis
Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China: a descriptive analysis Open
Background Joint contracture is the major clinical complication in burn patients, especially, the severe burn patients. This study aimed to investigate the number and severity of joint contractures in patients with burns affecting greater …
View article: Brain structure and neurological and behavioural functioning in infants born preterm
Brain structure and neurological and behavioural functioning in infants born preterm Open
Aim To examine: (1) relationships between brain structure, and concurrently assessed neurological and behavioural functioning, in infants born preterm at term‐equivalent age ( TEA ; approximately 38–44wks); and (2) whether brain structure–…
View article: Caffeine for apnea of prematurity and brain development at 11 years of age
Caffeine for apnea of prematurity and brain development at 11 years of age Open
Objective Caffeine therapy for apnea of prematurity has been reported to improve brain white matter microstructure at term‐equivalent age, but its long‐term effects are unknown. This study aimed to investigate whether caffeine affects (1) …
View article: Exploratory Use of Decision Tree Analysis in Classification of Outcome in Hypoxic–Ischemic Brain Injury
Exploratory Use of Decision Tree Analysis in Classification of Outcome in Hypoxic–Ischemic Brain Injury Open
Our findings provide proof of concept for further exploration of the role of MR imaging and decision tree analysis in the early prognostication of hypoxic ischemic brain injury.