Jicheng Lv
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View article: Association between preoperative anxiety and ciprofol requirements in women undergoing surgical abortion: a prospective observational study
Association between preoperative anxiety and ciprofol requirements in women undergoing surgical abortion: a prospective observational study Open
Objective To investigate the association between preoperative anxiety level and ciprofol consumption in patients undergoing surgical abortion. Methods A total of 144 patients scheduled for surgical abortion were enrolled and completed both…
View article: Challenges in clinical translation of artificial intelligence and real-time imaging navigation in radical gastrectomy
Challenges in clinical translation of artificial intelligence and real-time imaging navigation in radical gastrectomy Open
Radical gastrectomy for gastric cancer demands meticulous pre-operative staging and real-time intra-operative guidance to optimise oncologic margins and minimize complications. Recent advances in artificial-intelligence algorithms reliably…
View article: Proteomic analyses of the regulatory mechanisms underlying Pochonia chlamydosporia infection in Parascaris equorum eggs
Proteomic analyses of the regulatory mechanisms underlying Pochonia chlamydosporia infection in Parascaris equorum eggs Open
Background Pochonia chlamydosporia is an important egg-parasitic fungus with potential applications in the biological control of parasitic pests. However, the protein-response mechanisms during P. chlamydosporia infection of nematode eggs …
View article: #723 Predictive value of Gd-IgA1, poly-IgA in the treatment of IgA nephropathy with targeted−release formulation budesonide
#723 Predictive value of Gd-IgA1, poly-IgA in the treatment of IgA nephropathy with targeted−release formulation budesonide Open
Background and Aims Targeted release formulation (TRF)-budesonide (Nefecon), targeting the production of galactose-deficient IgA1 (Gd-IgA1) and IgA immune complex formation, has been approved for the treatment of IgA nephropathy (IgAN). In…
View article: #2009 Impact of systemic glucocorticoids on Gd-IgA1 levels in Immunoglobulin A Nephropathy: insights from the TESTING trial
#2009 Impact of systemic glucocorticoids on Gd-IgA1 levels in Immunoglobulin A Nephropathy: insights from the TESTING trial Open
Background and Aims Galactose-deficient IgA1 (Gd-IgA1) is a key player in the pathogenesis of Immunoglobulin A Nephropathy (IgAN), driving immune complex formation and subsequent kidney damage. The Therapeutic Effects of Steroids in IgA Ne…
View article: #1812 Efficacy and safety of telitacicept in IgA nephropathy and IgA vasculitis nephropathy in children: a retrospective single-center study
#1812 Efficacy and safety of telitacicept in IgA nephropathy and IgA vasculitis nephropathy in children: a retrospective single-center study Open
Background and Aims IgA nephropathy (IgAN) and IgA vasculitis nephropathy (IgAVN) are common renal diseases in children, with limited treatment options available. Telitacicept, a dual-targeted fusion protein, has shown potential in treatin…
View article: #110 Association between relapse and long-term kidney outcomes in IgA nephropathy
#110 Association between relapse and long-term kidney outcomes in IgA nephropathy Open
Background and Aims Relapse in IgA nephropathy (IgAN) remains under-researched. This study investigates the incidence of IgAN relapse, its association with adverse outcomes, and its risk factors within a prospective cohort. Method We analy…
View article: External Validation of the Post-Biopsy International IgA Nephropathy Prediction Tool Models over Extended Follow-Up in an Asian Cohort
External Validation of the Post-Biopsy International IgA Nephropathy Prediction Tool Models over Extended Follow-Up in an Asian Cohort Open
Introduction: The post-biopsy International IgA Nephropathy Prediction Tool (IIgAN-PT) models were updated to assess progression risk 1 or 2 years after biopsy. This study externally validated both models in a contemporary Asian cohort wit…
View article: Statin use and acute kidney injury among hospitalized chronic kidney disease patients: a retrospective cohort study
Statin use and acute kidney injury among hospitalized chronic kidney disease patients: a retrospective cohort study Open
Background Chronic kidney disease (CKD) constitutes a substantial burden in terms of cardiovascular disease and acute kidney injury (AKI). While statins are recommended for their cardiovascular benefits in CKD patients, their impact on AKI…
View article: Novel therapies improve prognosis of IgAN and limit the applicability of the International IgA Nephropathy Prediction Tool
Novel therapies improve prognosis of IgAN and limit the applicability of the International IgA Nephropathy Prediction Tool Open
Background The International IgA Nephropathy Prediction Tools using clinical variables and the Oxford MEST scores were developed in outdated cohorts. External validation is required to assess the tool's applicability in predicting progress…
View article: Predictive value of Gd-IgA1, poly-IgA in the treatment of IgA nephropathy with targeted-release formulation budesonide
Predictive value of Gd-IgA1, poly-IgA in the treatment of IgA nephropathy with targeted-release formulation budesonide Open
Background Targeted release formulation (TRF) budesonide (Nefecon), targeting galactose-deficient immunoglobulin A1 (Gd-IgA1) production and IgA immune complex formation, has been approved for IgA nephropathy (IgAN) treatment. In this stud…
View article: [Prospective association between physical activity and mortality in patients with chronic obstructive pulmonary disease].
[Prospective association between physical activity and mortality in patients with chronic obstructive pulmonary disease]. Open
Physical activity could reduce the mortality risk in a dose-response relationship among COPD patients, regardless of its intensity and type, especially among individuals aged 60 and above, females, and those with poor self-report health st…
View article: Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization
Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization Open
The findings of current study presented genetic proof for the potential protective effects of GLP1R agonists in the development of diabetic nephropathy and IgA nephropathy, offering a novel sight for future mechanistic and clinical applica…
View article: Repeated Kidney Biopsy in Membranoproliferative Glomerulonephritis
Repeated Kidney Biopsy in Membranoproliferative Glomerulonephritis Open
Introduction: Membranoproliferative glomerulonephritis (MPGN) is a heterogeneous pattern of glomerular injury. Repeated kidney biopsies may elucidate pathogenic mechanisms and guide diagnostic strategies. Methods: We included 82 patients d…
View article: Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis
Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis Open
Patients presenting monoclonal gammopathy of renal significance (MGRS) and IgA vasculitis collectively have rarely been reported. This study reports one patient with monoclonal IgA and λ, and with IgA positive-mesangial proliferative glome…
View article: Long-term evaluation of the timing of corticosteroid therapy in an IgA nephropathy cohort
Long-term evaluation of the timing of corticosteroid therapy in an IgA nephropathy cohort Open
Background Current proposed KDIGO guidelines suggest systemic corticosteroid therapy to reduce glomerular inflammation in immunoglobulin A nephropathy (IgAN), however the optimal timing for initiating steroid treatment remains a topic of d…
View article: Corticosteroid Effects in IgA Nephropathy by Baseline Proteinuria and Estimated GFR
Corticosteroid Effects in IgA Nephropathy by Baseline Proteinuria and Estimated GFR Open
Methylprednisolone improves kidney outcomes in IgAN at high risk of progression, irrespective of proteinuria or eGFR, although the risk-benefit balance may be less favorable in those with advanced disease plus other risk factors for cortic…
View article: In vitro ovicidal studies on egg-parasitic fungus Pochonia chlamydosporia and safety tests on mice
In vitro ovicidal studies on egg-parasitic fungus Pochonia chlamydosporia and safety tests on mice Open
Introduction The control of parasites infections in livestock is an ongoing concern, with parasites developing resistance to commonly used antiparasitic drugs. The current study investigated in vitro the destructive effect of the fungus Po…
View article: Development and validation of a real-time prediction model for acute kidney injury in hospitalized patients
Development and validation of a real-time prediction model for acute kidney injury in hospitalized patients Open
Early prediction of acute kidney injury (AKI) may provide a crucial opportunity for AKI prevention. To date, no prediction model targeting AKI among general hospitalized patients in developing countries has been published. Here we show a s…