Ji Yeon Baek
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View article: Trends and Socioeconomic Disparities in Polypharmacy and Potentially Inappropriate Medication Use among 66-Year-Olds in Korea: A Nationwide Study, 2012–2021
Trends and Socioeconomic Disparities in Polypharmacy and Potentially Inappropriate Medication Use among 66-Year-Olds in Korea: A Nationwide Study, 2012–2021 Open
Background: With increasing life expectancy, the number of older adults with multiple chronic conditions requiring complex medication regimens is growing, raising concerns about polypharmacy and potentially inappropriate medication (PIM) u…
View article: Long-Term Health and Cost Outcomes of a 24-Week Multicomponent Frailty Intervention in Older Adults
Long-Term Health and Cost Outcomes of a 24-Week Multicomponent Frailty Intervention in Older Adults Open
Importance While multicomponent frailty interventions have demonstrated short-term effectiveness, evidence on long-term health and cost outcomes is limited. Objective To evaluate the 66-month health and cost outcomes of a multicomponent fr…
View article: Voice-Based Remote Care Program for Vulnerable Older Adults in a Rural Community: Single-Arm Pilot Clinical Study
Voice-Based Remote Care Program for Vulnerable Older Adults in a Rural Community: Single-Arm Pilot Clinical Study Open
Background Voice-based digital health technologies are highly feasible and acceptable tools for supporting older adults. However, their development has rarely focused on caregiving needs, and it is often poorly integrated with existing car…
View article: Effect of a multicomponent intervention on institutionalization-free survival in older adults with sarcopenia: a post-hoc analysis
Effect of a multicomponent intervention on institutionalization-free survival in older adults with sarcopenia: a post-hoc analysis Open
Objectives To assess the effect of a 24-week comprehensive multicomponent intervention on institutionalization-free survival, physical performance, and frailty among older adults with sarcopenia. Design A post-hoc analysis of a prospective…
View article: Acute Care for Elders Risk Score: A Practical Machine Learning–Based Tool for Screening High-Risk Older Inpatients
Acute Care for Elders Risk Score: A Practical Machine Learning–Based Tool for Screening High-Risk Older Inpatients Open
The ACE Risk Score is a practical, interpretable, and scalable tool for early identification of high-risk older inpatients, using data available on the first day of admission. It supports timely, targeted interventions by geriatric teams. …
View article: Effect of a combined exercise and nutrition program on sarcopenia in older adults: a randomised controlled trial in primary care
Effect of a combined exercise and nutrition program on sarcopenia in older adults: a randomised controlled trial in primary care Open
Background Sarcopenia, marked by the progressive decline of skeletal muscle mass and strength, is a significant health issue in aging populations. Primary care-based interventions may offer effective management strategies, yet randomised c…
View article: The U-Shaped Association Between Serum Ferritin Levels and Frailty Risk in Older Adults: A Nationwide Population-Based Study (Preprint)
The U-Shaped Association Between Serum Ferritin Levels and Frailty Risk in Older Adults: A Nationwide Population-Based Study (Preprint) Open
BACKGROUND Ferritin, a key iron storage protein in the body, acts as an essential indicator of iron metabolism and is involved in various health conditions beyond hematologic disorders. Clinical evidence suggests that both elevated and re…
View article: Effect of Exercise and Nutrition Intervention for Older Adults with Impaired Physical Function with Preserved Muscle Mass (Functional Sarcopenia): A Randomized Controlled Trial
Effect of Exercise and Nutrition Intervention for Older Adults with Impaired Physical Function with Preserved Muscle Mass (Functional Sarcopenia): A Randomized Controlled Trial Open
The 12-week exercise and nutritional intervention significantly enhanced physical performance, grip strength, and quality of life among community-dwelling older adults with functional sarcopenia. This suggests that strategies commonly reco…
View article: Exploring the Barriers and Facilitators of Deprescribing in Older Adults: Qualitative Study of Patients and Geriatrics Experts
Exploring the Barriers and Facilitators of Deprescribing in Older Adults: Qualitative Study of Patients and Geriatrics Experts Open
Addressing barriers to deprescribing in South Korea requires a multifaceted approach, including public awareness campaigns, healthcare provider education, prescription sharing systems, and a geriatric primary care system. Long-term policie…
View article: Sex-Specific Influence of Preoperative Musculoskeletal Characteristics on Postoperative Outcomes in Lumbar Spinal Surgery: A Prospective Cohort Study
Sex-Specific Influence of Preoperative Musculoskeletal Characteristics on Postoperative Outcomes in Lumbar Spinal Surgery: A Prospective Cohort Study Open
These findings highlight the need for sex-specific preoperative assessments to improve surgical outcomes, suggesting that targeted preoperative interventions to enhance musculoskeletal health could benefit female patients undergoing lumbar…
View article: Circulating BMP-7 Level is Independent of Sarcopenia in Older Asian Adults
Circulating BMP-7 Level is Independent of Sarcopenia in Older Asian Adults Open
Background: In vitro and animal studies have demonstrated that bone morphogenetic protein-7 (BMP-7), renowned for its osteogenic properties, also exerts beneficial effects on muscle metabolism by enhancing myogenesis and reversing muscle a…
View article: Elevated Circulating Sclerostin Levels in Frail Older Adults: Implications beyond Bone Health
Elevated Circulating Sclerostin Levels in Frail Older Adults: Implications beyond Bone Health Open
Background: Sclerostin, initially recognized for its pivotal role in bone metabolism, has gained attention for its multifaceted impact on overall human health. However, its influence on frailty—a condition that best reflects biological age…
View article: Tuning Fast Memory Size based on Modeling of Page Migration for Tiered Memory
Tuning Fast Memory Size based on Modeling of Page Migration for Tiered Memory Open
Tiered memory, built upon a combination of fast memory and slow memory, provides a cost-effective solution to meet ever-increasing requirements from emerging applications for large memory capacity. Reducing the size of fast memory is valua…
View article: Higher serum uric acid as a risk factor for frailty in older adults: A nationwide population‐based study
Higher serum uric acid as a risk factor for frailty in older adults: A nationwide population‐based study Open
Background Uric acid (UA), the terminal breakdown product of purine metabolism, possesses contradictory roles, functioning both as an inflammatory mediator and as an antioxidant. Its clinical relevance, particularly in geriatric population…
View article: Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging
Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging Open
Static start underestimates gait speed, while dynamic start aligns better with other physical performance results. An acceleration phase of 0.5 to 1 meter appears sufficient, but further studies are needed to optimize gait measurement meth…
View article: Sarcopenia as the Mobility Phenotype of Aging: Clinical Implications
Sarcopenia as the Mobility Phenotype of Aging: Clinical Implications Open
Sarcopenia, which is characterized by an age-related decline in muscle mass and function, poses significant challenges to geriatric care. Its definition has evolved from muscle-specific criteria to include muscle mass, muscle function, and…
View article: Geriatric Medicine in South Korea: A Stagnant Reality amidst an Aging Population
Geriatric Medicine in South Korea: A Stagnant Reality amidst an Aging Population Open
In the face of an ever-increasing wave of an aging population, this paper provides an update on the current status of geriatric medicine in Korea, comparing it with global initiatives and suggesting future directions. Older adults require …
View article: A KEY DENDRITE DEVELOPMENT REGULATOR PLEXIN-A4 IS ASSOCIATED WITH DENDRITE MAINTENANCE IN AGED MICE
A KEY DENDRITE DEVELOPMENT REGULATOR PLEXIN-A4 IS ASSOCIATED WITH DENDRITE MAINTENANCE IN AGED MICE Open
There is significant loss of dendritic complexity with age, which may account for synaptic loss and cognitive decline in mammals. However, molecular mechanisms underlying these changes are unclear. Key molecular players in dendritic morpho…
View article: Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults
Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults Open
Background: Despite the protective effects of stromal cell-derived factor 1 (SDF-1) in stimulating muscle regeneration shown in experimental research, there is a lack of clinical studies linking circulating SDF-1 concentrations with muscle…
View article: Unmet Needs and Barriers in Providing Hospital Care for Older Adults: A Qualitative Study Using the Age-Friendly Health System Framework
Unmet Needs and Barriers in Providing Hospital Care for Older Adults: A Qualitative Study Using the Age-Friendly Health System Framework Open
The study highlighted the need for improvements in inpatient care for older adults at an academic hospital in Korea. Identified unmet needs and barriers can be used to guide a more patient-centered approaches for an age-friendly inpatient …
View article: Lack of association between serum myonectin levels and sarcopenia in older Asian adults
Lack of association between serum myonectin levels and sarcopenia in older Asian adults Open
Myonectin is a muscle-secreted factor that helps maintain homeostasis in the body by regulating several functions, including lipid metabolism. Previous studies suggested that myonectin may play a role in muscle health in an autocrine manne…
View article: Korean Working Group on Sarcopenia Guideline: Expert Consensus on Sarcopenia Screening and Diagnosis by the Korean Society of Sarcopenia, the Korean Society for Bone and Mineral Research, and the Korean Geriatrics Society
Korean Working Group on Sarcopenia Guideline: Expert Consensus on Sarcopenia Screening and Diagnosis by the Korean Society of Sarcopenia, the Korean Society for Bone and Mineral Research, and the Korean Geriatrics Society Open
Despite the introduction of a diagnostic code and acceptance of a diagnostic process for sarcopenia as a new health technology in Korea, many practitioners remain unfamiliar with the evaluation of sarcopenia. Thus, the Korean Working Group…
View article: At-Point Clinical Frailty Scale as a Universal Risk Tool for Older Inpatients in Acute Hospital: A Cohort Study
At-Point Clinical Frailty Scale as a Universal Risk Tool for Older Inpatients in Acute Hospital: A Cohort Study Open
Background While the Clinical Frailty Scale (CFS) has been extensively validated for predicting health outcomes in older adults, the role of the at-point CFS at the time of examination is unclear. We aimed to examine the ability of the at-…
View article: A Comparative Study of High-Frequency Bioelectrical Impedance Analysis and Dual-Energy X-ray Absorptiometry for Estimating Body Composition
A Comparative Study of High-Frequency Bioelectrical Impedance Analysis and Dual-Energy X-ray Absorptiometry for Estimating Body Composition Open
Though bioelectrical impedance analysis (BIA) is a favorable tool for assessing body composition to estimate nutritional status and physical fitness, such as sarcopenia, there are accuracy issues. Hence, high-frequency (HF) BIA equipment u…
View article: Operationalization of the Clinical Frailty Scale in Korean Community-Dwelling Older People
Operationalization of the Clinical Frailty Scale in Korean Community-Dwelling Older People Open
Background The Clinical Frailty Scale (CFS) is a simple measure of global fitness validated in various populations in real-world settings. In this study, we aimed to assess the characteristics and validities of the CFS in community-dwellin…