Ji Yong Ahn
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View article: Risk factors for bleeding from gastric antral vascular ectasia
Risk factors for bleeding from gastric antral vascular ectasia Open
Background/Aims: Gastric antral vascular ectasia (GAVE) is a rare but important cause of gastrointestinal (GI) bleeding. The clinical course of GAVE is not well-known, and recurrent bleeding from GAVE is a therapeutic challenge. Therefore,…
View article: Clinical management of gastric mucosa-associated lymphoid tissue lymphoma
Clinical management of gastric mucosa-associated lymphoid tissue lymphoma Open
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often associated with chronic Helicobacter pylori infection. For an accurate diagnosis of gastric MALT lymphoma, clinical suspicion and careful endoscopic examination with multip…
View article: Establishing Epidemiological Cutoff Values for <i>Helicobacter pylori</i> Strains in Korea: A Model-Based Analysis of Antibiotic Resistance Patterns
Establishing Epidemiological Cutoff Values for <i>Helicobacter pylori</i> Strains in Korea: A Model-Based Analysis of Antibiotic Resistance Patterns Open
This comprehensive analysis defined regional antibiotic resistance patterns and established Korea-specific ECOFFs, providing a foundation for determining clinical breakpoints and optimizing H. pylori eradication strategies.
View article: Characteristics Associated With Spontaneous Helicobacter pylori Clearance After Subtotal Gastrectomy in Patients With Gastric Cancer
Characteristics Associated With Spontaneous Helicobacter pylori Clearance After Subtotal Gastrectomy in Patients With Gastric Cancer Open
Objectives: Helicobacter pylori eradication treatment typically occurs after gastrectomy; however, the specific criteria for eradication treatment have not been reported. This study aimed to evaluate the rates and locations of spontaneous …
View article: Pharmacological Treatment of Gastritis: A Narrative Review with a Systematic Literature Search
Pharmacological Treatment of Gastritis: A Narrative Review with a Systematic Literature Search Open
Gastritis, characterized by gastric mucosal inflammation, is a common gastrointestinal disorder with diverse etiologies, such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs use, and autoimmune conditions. Pharmacolo…
View article: Validation of Lyon 2.0 Gastroesophageal Reflux Disease Consensus: Limited Clinical Utility of Mean Nocturnal Basal Impedance in Koreans
Validation of Lyon 2.0 Gastroesophageal Reflux Disease Consensus: Limited Clinical Utility of Mean Nocturnal Basal Impedance in Koreans Open
MNBI significantly correlated with AET and LA grades, highlighting its diagnostic value in Korean GERD patients. However, regional variations suggest higher MNBI thresholds than Lyon 2.0 recommendations, warranting further studies to refin…
View article: Distribution and Clinical Impact of Helicobacter pylori Virulence Factors in Epstein–Barr-Virus-Associated Gastric Cancer
Distribution and Clinical Impact of Helicobacter pylori Virulence Factors in Epstein–Barr-Virus-Associated Gastric Cancer Open
Background: Helicobacter pylori (HP) and Epstein–Barr virus (EBV) coinfection lead to chronic inflammation and contribute to the development of gastric cancer. However, studies examining the association between HP virulence factors and EBV…
View article: Effect of Helicobacter pylori eradication on remnant stomach neoplasms after curative gastrectomy (HELP-GC): Protocol of a HELP-GC randomized controlled trial
Effect of Helicobacter pylori eradication on remnant stomach neoplasms after curative gastrectomy (HELP-GC): Protocol of a HELP-GC randomized controlled trial Open
Background Limited research has examined the direct effectiveness of Helicobacter pylori eradication (HPE) on the remnant stomach neoplasms after curative gastrectomy. This study aims to assess whether HPE could prevent the development of …
View article: Korean Registry on the Current Management of <i>Helicobacter pylori</i> (K-Hp-Reg): Interim Analysis of Adherence to the Revised Evidence-Based Guidelines for First-Line Treatment
Korean Registry on the Current Management of <i>Helicobacter pylori</i> (K-Hp-Reg): Interim Analysis of Adherence to the Revised Evidence-Based Guidelines for First-Line Treatment Open
The revised guidelines for the treatment of H. pylori infection have been increasingly adopted in routine clinical practice in Korea, which may have contributed to improved first-line eradication rates. Notably, the 14-day CTT, 10-day CT, …
View article: Effect of <i>Helicobacter pylori</i> Eradication on Metabolic Parameters and Body Composition including Skeletal Muscle Mass: A Matched Case-Control Study
Effect of <i>Helicobacter pylori</i> Eradication on Metabolic Parameters and Body Composition including Skeletal Muscle Mass: A Matched Case-Control Study Open
H. pylori eradication significantly reduced blood pressure, glucose levels, and systemic inflammation and improved lipid profiles in patients aged >45 years. BMI, body fat mass, ASM, and waist circumference did not significantly differ bet…
View article: Clinical Advances in Percutaneous Endoscopic Gastrostomy: A 2023 Clinical Practice Guideline-Based Review
Clinical Advances in Percutaneous Endoscopic Gastrostomy: A 2023 Clinical Practice Guideline-Based Review Open
Percutaneous endoscopic gastrostomy (PEG) has become a standard method for enteral nutrition in patients with swallowing difficulties due to various medical conditions, including neurodegenerative diseases, stroke, and malignancies. While …
View article: Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients
Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients Open
Background/Aims: Cytomegalovirus (CMV) disease in the upper gastrointestinal (UGI) tract frequently occurs in immunocompromised patients. However, data regarding UGI CMV disease in non-transplant patients compared with those in transplant …
View article: Sex Differences in Clinical Features and Survival Outcomes of Esophageal Cancer: A Comparative Study in the Korean Population
Sex Differences in Clinical Features and Survival Outcomes of Esophageal Cancer: A Comparative Study in the Korean Population Open
We found significant sex differences in esophageal cancer among the Korean population, with female patients demonstrating distinct clinical characteristics and more favorable survival outcomes compared to male patients. These findings unde…
View article: In Vitro Susceptibility and Synergistic Effect of Bismuth Against Helicobacter pylori
In Vitro Susceptibility and Synergistic Effect of Bismuth Against Helicobacter pylori Open
Background/objectives: Bismuth is commonly used in Helicobacter pylori (H. pylori) eradication therapy. However, few studies have examined the in vitro susceptibility of H. pylori to bismuth. Moreover, the exact mechanism of action of bism…
View article: Optimal Diagnostic and Treatment Response Threshold of the Eosinophilic Esophagitis Endoscopic Reference Score: A Single-Center Study of 102 Patients With Eosinophilic Esophagitis
Optimal Diagnostic and Treatment Response Threshold of the Eosinophilic Esophagitis Endoscopic Reference Score: A Single-Center Study of 102 Patients With Eosinophilic Esophagitis Open
The optimal diagnostic and treatment response thresholds were determined to be endoscopic reference scores of ≥ 2 and ≤ 3, respectively. Further studies involving a larger patient cohort are necessary to validate these findings.
View article: Additional Diagnostic Yield of the Rapid Drink Challenge in Chicago Classification Version 4.0 Compared With Version 3.0
Additional Diagnostic Yield of the Rapid Drink Challenge in Chicago Classification Version 4.0 Compared With Version 3.0 Open
Chicago classification 4.0 increased the diagnostic yield of the rapid drink challenge by 2.0% (9/453 patients). However, the rapid drink challenge had a failure rate of 17.9% (99/552 patients). Given the relatively low diagnostic yield an…
View article: Prevention of Gastric Cancer: Helicobacter pylori Treatment
Prevention of Gastric Cancer: Helicobacter pylori Treatment Open
Helicobacter pylori infection has been associated with various gastric diseases, including ulcers, adenomas, and adenocarcinomas. Over 40 years since the discovery of H. pylori, numerous studies have shown that H. pylori eradication therap…
View article: Culture‐based susceptibility‐guided tailored versus empirical concomitant therapy as first‐line <i>Helicobacter pylori</i> treatment: A randomized clinical trial
Culture‐based susceptibility‐guided tailored versus empirical concomitant therapy as first‐line <i>Helicobacter pylori</i> treatment: A randomized clinical trial Open
Background With the increasing resistance to antimicrobial agents, susceptibility‐guided tailored therapy has been emerging as an ideal strategy for Helicobacter pylori treatment. However, susceptibility‐guided tailored therapy requires ad…
View article: Clinical course of asymptomatic duodenal subepithelial lesions
Clinical course of asymptomatic duodenal subepithelial lesions Open
Background/Aims: There is limited knowledge regarding the management of duodenal subepithelial lesions (SELs) owing to a lack of understanding of their natural course. This study aimed to assess the natural course of asymptomatic duodenal …
View article: Endoscopic diagnosis of eosinophilic esophagitis using a multi-task U-Net: A pilot study
Endoscopic diagnosis of eosinophilic esophagitis using a multi-task U-Net: A pilot study Open
Background and Aims: Endoscopically identifying eosinophilic esophagitis (EoE) is difficult because of its rare incidence and subtle morphology. We aim to develop a robust and accurate convolutional neural network (CNN) model for EoE ident…
View article: Predicting Helicobacter pylori infection from endoscopic features
Predicting Helicobacter pylori infection from endoscopic features Open
Background: Helicobacter pylori infection, prevalent in more than half of the global population, is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The effectiveness of early diagnosis and tre…
View article: Endoscopic resection of gastric gastrointestinal stromal tumor using clip-and-cut endoscopic full-thickness resection: a single-center, retrospective cohort in Korea
Endoscopic resection of gastric gastrointestinal stromal tumor using clip-and-cut endoscopic full-thickness resection: a single-center, retrospective cohort in Korea Open
Background/Aims: To overcome the technical limitations of classic endoscopic resection for gastric gastrointestinal stromal tumors (GISTs), various methods have been developed. In this study, we examined the role and feasibility of clip-an…
View article: A Modified eCura System to Stratify the Risk of Lymph Node Metastasis in Undifferentiated-Type Early Gastric Cancer After Endoscopic Resection
A Modified eCura System to Stratify the Risk of Lymph Node Metastasis in Undifferentiated-Type Early Gastric Cancer After Endoscopic Resection Open
The eCuraU system stratified the risk of LNM in patients with UD-EGC after ER. It is strongly recommended that high-risk patients undergo additional surgery.
View article: Comparison of Helicobacter pylori Eradication Rates Using Standard Triple Therapy and Sequential Therapy
Comparison of Helicobacter pylori Eradication Rates Using Standard Triple Therapy and Sequential Therapy Open
Objectives: The incidence of treatment failures following standard triple therapy (STT) for Helicobacter pylori eradication (HPE) has reached an unacceptable level. Sequential therapy (SQ) has emerged as a promising approach to counteract …
View article: Differential Diagnosis of Thickened Gastric Wall between Hypertrophic Gastritis and Borrmann Type 4 Advanced Gastric Cancer
Differential Diagnosis of Thickened Gastric Wall between Hypertrophic Gastritis and Borrmann Type 4 Advanced Gastric Cancer Open
: Endoscopic findings of a thickened gastric wall, including antral involvement, and presence of ulcer were significant risk factors for the diagnosis of AGC B-4. EUS findings of destroyed wall layers and a thickened PM of >2.39 mm were th…
View article: Corrigendum to: External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection
Corrigendum to: External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection Open
Background/Aims: The combinatorial effects of prophylactic methods for postendoscopic retrograde cholangiopancreatography pancreatitis (PEP) in patients with risk factors remain unclear. In this network meta-analysis, we compared the effic…