Jia Ying Loh
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View article: Dynein Adaptors Such as Drosophila Bicaudal (Dm BicD) Recognize Cargo and are Required to Activate Dynein for Processive Transport
Dynein Adaptors Such as Drosophila Bicaudal (Dm BicD) Recognize Cargo and are Required to Activate Dynein for Processive Transport Open
View article: Coiled‐coil registry shifts in the <scp>F684I</scp> mutant of Bicaudal D result in cargo‐independent activation of dynein motility
Coiled‐coil registry shifts in the <span>F684I</span> mutant of Bicaudal D result in cargo‐independent activation of dynein motility Open
The dynein adaptor Drosophila Bicaudal D (BicD) is auto‐inhibited and activates dynein motility only after cargo is bound, but the underlying mechanism is elusive. In contrast, we show that the full‐length BicD/F684I mutant activates dynei…
View article: Author response for "Coiled‐coil registry shifts in the <scp>F684I</scp> mutant of Bicaudal D result in cargo‐independent activation of dynein motility"
Author response for "Coiled‐coil registry shifts in the <span>F684I</span> mutant of Bicaudal D result in cargo‐independent activation of dynein motility" Open
View article: Author response for "Coiled‐coil registry shifts in the <scp>F684I</scp> mutant of Bicaudal D result in cargo‐independent activation of dynein motility"
Author response for "Coiled‐coil registry shifts in the <span>F684I</span> mutant of Bicaudal D result in cargo‐independent activation of dynein motility" Open
View article: Coiled-coil registry shifts in the F684I mutant of Bicaudal result in cargo-independent activation of dynein motility
Coiled-coil registry shifts in the F684I mutant of Bicaudal result in cargo-independent activation of dynein motility Open
The dynein adaptor Drosophila Bicaudal D (BicD) is auto-inhibited and activates dynein motility only after cargo is bound, but the underlying mechanism is elusive. In contrast, we show that the full-length BicD/F684I mutant activates dynei…
View article: Role of Coiled-Coil Registry Shifts in the Activation of Human Bicaudal D2 for Dynein Recruitment upon Cargo Binding
Role of Coiled-Coil Registry Shifts in the Activation of Human Bicaudal D2 for Dynein Recruitment upon Cargo Binding Open
Dynein adaptors such as Bicaudal D2 (BicD2) recognize cargo for dynein-dependent transport, and cargo-bound adaptors are required to activate dynein for processive transport, but the mechanism of action is unknown. Here we report the X-ray…
View article: Role of coiled-coil registry shifts in activation of human Bicaudal D2 for dynein recruitment upon cargo-binding
Role of coiled-coil registry shifts in activation of human Bicaudal D2 for dynein recruitment upon cargo-binding Open
SUMMARY Dynein adaptors such as Bicaudal D2 (BicD2) recognize cargo for dynein-dependent transport. BicD2-dependent transport pathways are important for brain and muscle development. Cargo-bound adaptors are required to activate dynein for…