Jiabao Liao
YOU?
Author Swipe
View article: New Trends and Hot Spots in the Study of Diabetic Peripheral Neuropathy: A Bibliometric Analysis
New Trends and Hot Spots in the Study of Diabetic Peripheral Neuropathy: A Bibliometric Analysis Open
Objective: Diabetic Peripheral Neuropathy (DPN) is a common chronic complication of diabetes that currently has no therapeutic recourse. Advanced DPN stages are characterized by severe symptoms that place a huge burden on patients and heal…
View article: Jejunoileal side-to-side anastomosis: New hope for patients with type 2 diabetes?
Jejunoileal side-to-side anastomosis: New hope for patients with type 2 diabetes? Open
In this article, we comment on an article by Wang et al published in the World Journal of Diabetes . Existing treatments with oral medications can partially mitigate the toxicity of elevated blood glucose levels in patients with type 2 dia…
View article: Correlation of organelle interactions in the development of non-alcoholic fatty liver disease
Correlation of organelle interactions in the development of non-alcoholic fatty liver disease Open
Organelles, despite having distinct functions, interact with each other. Interactions between organelles typically occur at membrane contact sites (MCSs) to maintain cellular homeostasis, allowing the exchange of metabolites and other piec…
View article: Plantamajoside Promotes <scp>NGF</scp>/<scp>TrkA</scp> Pathway to Inhibit Neuronal Apoptosis and Improve Diabetic Peripheral Neuropathy
Plantamajoside Promotes <span>NGF</span>/<span>TrkA</span> Pathway to Inhibit Neuronal Apoptosis and Improve Diabetic Peripheral Neuropathy Open
The symptoms caused by diabetic peripheral neuropathy (DPN) have severely impacted patients' quality of life. While plantamajoside (PMS) exhibits neuroprotective properties, its efficacy and molecular mechanisms against DPN are unexplored.…
View article: Alisol B 23‐Acetate Down‐Regulated GRP94 to Restore Endoplasmic Reticulum Homeostasis on Non‐Alcoholic Steatohepatitis
Alisol B 23‐Acetate Down‐Regulated GRP94 to Restore Endoplasmic Reticulum Homeostasis on Non‐Alcoholic Steatohepatitis Open
Non‐alcoholic steatohepatitis (NASH) poses a serious threat to human health. Alisol B 23‐Acetate (AB23A) has shown beneficial effects on NASH, but its mechanism of action remains unclear. We conducted in vitro experiments by inducing L02 c…
View article: Esculetin rebalances <scp>M1</scp>/<scp>M2</scp> macrophage polarization to treat sepsis‐induced acute lung injury through regulating metabolic reprogramming
Esculetin rebalances <span>M1</span>/<span>M2</span> macrophage polarization to treat sepsis‐induced acute lung injury through regulating metabolic reprogramming Open
Sepsis‐induced acute lung injury (SALI) is characterized by a high incidence and mortality rate, which has caused a serious medical burden. The pharmacological effects of esculetin (ELT), such as antibacterial and anti‐inflammatory actions…
View article: Insight into the mystery of Pheretima smells worse exposed to water: Identification, type, and volatility of stenchy odor
Insight into the mystery of Pheretima smells worse exposed to water: Identification, type, and volatility of stenchy odor Open
Pheretima is a popular healthy food, but Pheretima and related foods have specific stenchy odor, especially after decocting or warm soaking, the odor is intense, resulting in nausea and vomiting. This indicates that the release of stenchy …
View article: JoVE Video Dataset
JoVE Video Dataset Open
An erratum was issued for: An Improved Technique for Trimethylamine Detection in Animal-Derived Medicine by Headspace Gas Chromatography-Tandem Quadrupole Mass Spectrometry. The Authors section was updated from:
View article: Changes of mitochondrial dynamics during the progression of non-alcoholic fatty liver disease: a review
Changes of mitochondrial dynamics during the progression of non-alcoholic fatty liver disease: a review Open
View article: Natural regulatory T cells and bifunctional regulatory T cells: potential targets of traditional Chinese medicine in treating colitis-associated colon cancer
Natural regulatory T cells and bifunctional regulatory T cells: potential targets of traditional Chinese medicine in treating colitis-associated colon cancer Open
View article: Aqueous extract of Polygala japonica Houtt. ameliorated nonalcoholic steatohepatitis in mice through restoring the gut microbiota disorders and affecting the metabolites in feces and liver
Aqueous extract of Polygala japonica Houtt. ameliorated nonalcoholic steatohepatitis in mice through restoring the gut microbiota disorders and affecting the metabolites in feces and liver Open
Our study demonstrated the therapeutic, anti-inflammatory and anti-oxidative potentials of PJ on NASH. The mechanisms of PJ treatment were related to the improvement of gut microbiota dysbiosis and the regulation of histidine and tryptopha…
View article: Polygalasaponin F ameliorates middle cerebral artery occlusion-induced focal ischemia in rats through inhibiting TXNIP/NLRP3 signaling pathway
Polygalasaponin F ameliorates middle cerebral artery occlusion-induced focal ischemia in rats through inhibiting TXNIP/NLRP3 signaling pathway Open
Polygalasaponin F (PGSF), an oleanane triterpenoid saponin extracted from Polygala japonica , has been demonstrated with neuroprotective effect. However, the therapeutic effects and mechanism of PGSF on focal ischemia remain unknown. In th…
View article: Mechanic study of Qushi Kaiyu decoction on non-alcoholic fatty liver disease model rats based on the inhibition of TLR4/NF-ĸB pathway
Mechanic study of Qushi Kaiyu decoction on non-alcoholic fatty liver disease model rats based on the inhibition of TLR4/NF-ĸB pathway Open
View article: Formononetin Promotes Fatty Acid Β-Oxidation to Treat Non-Alcoholic Steatohepatitis Through SIRT1/PGC-1α/PPARα Pathway
Formononetin Promotes Fatty Acid Β-Oxidation to Treat Non-Alcoholic Steatohepatitis Through SIRT1/PGC-1α/PPARα Pathway Open
View article: Repairing mitochondrial dysfunction: potential mechanisms of natural products in the treatment of NAFLD
Repairing mitochondrial dysfunction: potential mechanisms of natural products in the treatment of NAFLD Open
View article: Jian-Ti-Kang-Yi decoction alleviates poly(I:C)-induced pneumonia by inhibiting inflammatory response, reducing oxidative stress, and modulating host metabolism
Jian-Ti-Kang-Yi decoction alleviates poly(I:C)-induced pneumonia by inhibiting inflammatory response, reducing oxidative stress, and modulating host metabolism Open
Jian-Ti-Kang-Yi decoction (JTKY) is widely used in the treatment of COVID-19. However, the protective mechanisms of JTKY against pneumonia remain unknown. In this study, polyinosinic-polycytidylic acid (poly(I:C)), a mimic of viral dsRNA, …
View article: Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism Open
Viral pneumonia is widespread, progresses rapidly, and has a high mortality rate. Developing safe and effective therapies to treat viral pneumonia can minimize risks to public health and alleviate pressures on the associated health systems…
View article: Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics
Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics Open
Jian-Gan-Xiao-Zhi decoction (JGXZ) has demonstrated beneficial effects on nonalcoholic fatty liver disease (NAFLD). However, the mechanisms by which JGXZ improve NAFLD are still unclear. Methods. In this study, we first used a high-fat diet …
View article: Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism
Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism Open
Qing-Wen-Jie-Re mixture (QWJR) has been used in the treatment of the coronavirus disease 2019 (COVID-19) in China. However, the protective mechanisms of QWJR on viral pneumonia remain unclear. In the present study, we first investigated th…
View article: Effect of Jiangan Xiaozhi decoction on endoplasmic reticulum stress signaling pathway in methionine and choline deficiency diet-induced mice
Effect of Jiangan Xiaozhi decoction on endoplasmic reticulum stress signaling pathway in methionine and choline deficiency diet-induced mice Open
View article: Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats
Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats Open
In this study, therapeutic, anti-inflammatory and anti-oxidative and metabolic regulatory effects of evodiamine on type 2 diabetes mellitus model rats were studied.
View article: Advances in traditional Chinese medicine for liver disease therapy in 2021
Advances in traditional Chinese medicine for liver disease therapy in 2021 Open
View article: Effects of Qingwen Baidu decoction on coagulation and multiple organ injury in rat models of sepsis
Effects of Qingwen Baidu decoction on coagulation and multiple organ injury in rat models of sepsis Open
View article: Effects of nuciferine on Nrf2/HO-1 signaling pathway in adipose tissue of obesity model rats
Effects of nuciferine on Nrf2/HO-1 signaling pathway in adipose tissue of obesity model rats Open
View article: Integration of multi-omics in investigations on the mechanisms of action of Chinese herbal medicine interventions in metabolic diseases
Integration of multi-omics in investigations on the mechanisms of action of Chinese herbal medicine interventions in metabolic diseases Open
View article: Pi-Dan-Jian-Qing Decoction Ameliorates Type 2 Diabetes Mellitus Through Regulating the Gut Microbiota and Serum Metabolism
Pi-Dan-Jian-Qing Decoction Ameliorates Type 2 Diabetes Mellitus Through Regulating the Gut Microbiota and Serum Metabolism Open
Pi-Dan-Jian-Qing decoction (PDJQ) can been used in the treatment of type 2 diabetes mellitus (T2DM) in clinic. However, the protective mechanisms of PDJQ on T2DM remain unknown. Recent studies have shown that the changes in gut microbiota …
View article: Jiangtangjing ameliorates type 2 diabetes through effects on the gut microbiota and cAMP/PKA pathway
Jiangtangjing ameliorates type 2 diabetes through effects on the gut microbiota and cAMP/PKA pathway Open
View article: Jian-Gan-Xiao-Zhi Decoction Alleviates Inflammatory Response in Nonalcoholic Fatty Liver Disease Model Rats through Modulating Gut Microbiota
Jian-Gan-Xiao-Zhi Decoction Alleviates Inflammatory Response in Nonalcoholic Fatty Liver Disease Model Rats through Modulating Gut Microbiota Open
Background. Jian-Gan-Xiao-Zhi decoction (JGXZ), composed of Salvia miltiorrhiza Bunge, Panax notoginseng, Curcuma zedoaria, and other 9 types of herbs, has demonstrated beneficial effects on nonalcoholic fatty liver disease (NAFLD). Howeve…
View article: Jian-Gan-Xiao-Zhi decoction ameliorates high-fat high-carbohydrate diet-induced non-alcoholic fatty liver disease and insulin resistance by regulating the AMPK/JNK pathway
Jian-Gan-Xiao-Zhi decoction ameliorates high-fat high-carbohydrate diet-induced non-alcoholic fatty liver disease and insulin resistance by regulating the AMPK/JNK pathway Open
View article: Advances in traditional Chinese medicine for liver disease therapy in 2020
Advances in traditional Chinese medicine for liver disease therapy in 2020 Open