Jiabo Li
YOU?
Author Swipe
View article: Performance comparison of four exome capture platforms on DNBSEQ-Series high throughput sequencer
Performance comparison of four exome capture platforms on DNBSEQ-Series high throughput sequencer Open
Whole exome sequencing (WES) technology has become a prevalent methodology in the field of human genetics research, providing an effective and affordable alternative to identify causative genetic mutations in genomic exon regions. This stu…
View article: Supplementary material to "Driving Factors of Oxalic Acid and Enhanced Role of Gas-Phase Oxidation under Cleaner Conditions: Insights from 2007–2018 Field Observations in the Pearl River Delta"
Supplementary material to "Driving Factors of Oxalic Acid and Enhanced Role of Gas-Phase Oxidation under Cleaner Conditions: Insights from 2007–2018 Field Observations in the Pearl River Delta" Open
View article: Simultaneously Computing a Maximal Independent Set Modulo an Ideal and a Gröbner Basis of the Ideal
Simultaneously Computing a Maximal Independent Set Modulo an Ideal and a Gröbner Basis of the Ideal Open
To solve problems on a positive-dimensional ideal, I⊂k[X], a maximal independent set U⊂X modulo I, and a Gröbner basis of Ie, where Ie is the extension of I to k(U)[V](V:=X∖U), are widely used. As far as we know, they are usually computed …
View article: Research on the Surface Deformation Law with the Mining Process of Tangjiazhuang Iron Mine Based on FLAC3D
Research on the Surface Deformation Law with the Mining Process of Tangjiazhuang Iron Mine Based on FLAC3D Open
In view of the current situation that the mining process of underground mines is easy to induce surface deformation, which leads to cracking and deformation of surface structures, this paper uses finite difference numerical analysis softwa…
View article: Computing a Maximal Independent Set Modulo an Ideal and a Gröbner Basis of the Ideal Simultaneously
Computing a Maximal Independent Set Modulo an Ideal and a Gröbner Basis of the Ideal Simultaneously Open
To solve problems on a positive-dimensional ideal I ⊂ k[X], a maximal independent set U ⊂ X modulo I and a Gröbner basis of Ie, where Ie is the extension of I to k(U)[V] (V := X\U), are widely used. As far as we know, they are usually comp…
View article: Supplementary material to "Long–term Trends in PM <sub>2.5</sub> Chemical Composition and Its Impact on Aerosol Properties: Field Observations from 2007 to 2020 in Pearl River Delta, South China"
Supplementary material to "Long–term Trends in PM <sub>2.5</sub> Chemical Composition and Its Impact on Aerosol Properties: Field Observations from 2007 to 2020 in Pearl River Delta, South China" Open
View article: Long–term Trends in PM <sub>2.5</sub> Chemical Composition and Its Impact on Aerosol Properties: Field Observations from 2007 to 2020 in Pearl River Delta, South China
Long–term Trends in PM <sub>2.5</sub> Chemical Composition and Its Impact on Aerosol Properties: Field Observations from 2007 to 2020 in Pearl River Delta, South China Open
Long–term data of PM2.5 chemical composition provide essential information for evaluating the effectiveness of air pollution control measures and understanding the evolving mechanisms of secondary species formation in the real atmosphere. …
View article: Perturbations in the microbiota-gut-brain axis shaped by social status loss
Perturbations in the microbiota-gut-brain axis shaped by social status loss Open
Social status is closely linked to physiological and psychological states. Loss of social dominance can lead to brain disorders such as depression, but the underlying mechanisms remain unclear. The gut microbiota can sense stress and contr…
View article: A clinically relevant model and method to study necrosis as a driving force in glioma restructuring and progression
A clinically relevant model and method to study necrosis as a driving force in glioma restructuring and progression Open
All glioblastoma (GBM) molecular subsets share the common trait of accelerated progression following necrosis, which cannot be adequately explained by cellular proliferation arising from accumulated genetic alterations. Counter to dogma th…
View article: Inhibition of Mesenchymal Phenotypes in Glioblastoma by Combined Targeting of NF-κB and STAT3 Pathways
Inhibition of Mesenchymal Phenotypes in Glioblastoma by Combined Targeting of NF-κB and STAT3 Pathways Open
Glioblastoma, IDH-wildtype (GBM, WHO grade 4) is the most common and lethal type of brain cancer that is hard to cure. Among the 3 subtypes of GBM, the mesenchymal GBM is characterized by therapeutic resistance and poor outcomes. Here, we …
View article: Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI
Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI Open
Neutrophils from skull bone marrow (Nskull) are activated under some brain stresses, but their effects on traumatic brain injury (TBI) are lacking. Here, we find Nskull infiltrates brain tissue quickly and persistentl…
View article: Antibacterial Activity and Action Mechanism of Bacteriocin Paracin wx7 as a Selective Biopreservative against Vancomycin-Resistant Enterococcus faecalis in Fresh-Cut Lettuce
Antibacterial Activity and Action Mechanism of Bacteriocin Paracin wx7 as a Selective Biopreservative against Vancomycin-Resistant Enterococcus faecalis in Fresh-Cut Lettuce Open
Fresh-cut vegetables are widely consumed, but there is no food preservative available to selectively inhibit vancomycin-resistant E. faecalis, which is a serious health menace in fresh-cut vegetables. To develop a promising food biopreserv…
View article: FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury
FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury Open
View article: Role of ferroptosis in <i>Porphyromonas gingivalis-</i> induced impairment of epithelial junction
Role of ferroptosis in <i>Porphyromonas gingivalis-</i> induced impairment of epithelial junction Open
Our study demonstrated that P. gingivalis weakened the oral epithelial barrier by causing ferroptosis via inhibiting SLC7A11/GSH/GPX4 axis.
View article: Effects of postweaning cadmium exposure on socioemotional behaviors in adolescent male mice
Effects of postweaning cadmium exposure on socioemotional behaviors in adolescent male mice Open
Exposure to cadmium (Cd), a toxic heavy metal classified as an environmental endocrine disruptor, can exert significant toxicity in both animals and humans. However, the potential effects of Cd exposure on socioemotional behaviors are stil…
View article: Correction: TMEM158 promotes the proliferation and migration of glioma cells via STAT3 signaling in glioblastomas
Correction: TMEM158 promotes the proliferation and migration of glioma cells via STAT3 signaling in glioblastomas Open
Following the publication of this article, reuse of an image was noted in Figures 3J and3N depicting the migration and invasion of the sh-TMEM158-1 treated group in the U251MG cell line.Upon reviewing these figures alongside the original d…
View article: TCAF2 drives glioma cellular migratory/invasion properties through STAT3 signaling
TCAF2 drives glioma cellular migratory/invasion properties through STAT3 signaling Open
View article: STEM-05. HYPOXIA AND ACIDOSIS PROMOTE YAP/TAZ ACTIVATION, POTENTIALLY SUPPORTING GLIOMA STEM CELL MAINTENANCE IN THE PERI-NECROTIC ZONES
STEM-05. HYPOXIA AND ACIDOSIS PROMOTE YAP/TAZ ACTIVATION, POTENTIALLY SUPPORTING GLIOMA STEM CELL MAINTENANCE IN THE PERI-NECROTIC ZONES Open
Glioblastoma (GBM) is a highly malignant brain tumor characterized by rapid growth and poor clinical outcomes. The development of necrosis is associated with massive tumor microenvironment (TME) reshaping and rapid progression characterize…
View article: TMIC-14. CLEC5A REGULATES TAM POLARIZATION, TME IMMUNOSUPPRESSION AND DISEASE PROGRESSION IN GLIOBLASTOMA
TMIC-14. CLEC5A REGULATES TAM POLARIZATION, TME IMMUNOSUPPRESSION AND DISEASE PROGRESSION IN GLIOBLASTOMA Open
Glioblastoma, IDH-wildtype (WHO grade 4) is the most common primary malignant brain tumor of adults and is characterized by an immunosuppressive tumor microenvironment (TME) and poor clinical outcomes. CLEC5A is a gene whose expression enh…
View article: Multimodal data fusion for supervised learning-based identification of USP7 inhibitors: a systematic comparison
Multimodal data fusion for supervised learning-based identification of USP7 inhibitors: a systematic comparison Open
Ubiquitin-specific-processing protease 7 (USP7) is a promising target protein for cancer therapy, and great attention has been given to the identification of USP7 inhibitors. Traditional virtual screening methods have now been successfully…
View article: Broadband Tunable Infrared Emission of Ni2+-Doped Znga/Alo4 Integrated Transparent Glass Ceramics
Broadband Tunable Infrared Emission of Ni2+-Doped Znga/Alo4 Integrated Transparent Glass Ceramics Open
View article: PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma Open
View article: TMIC-21. THE ROLE OF CLEC5A ON M2-LIKE TUMOR-ASSOCIATED MACROPHAGES POLARIZATION AND DISEASE PROGRESSION IN GLIOBLASTOMA
TMIC-21. THE ROLE OF CLEC5A ON M2-LIKE TUMOR-ASSOCIATED MACROPHAGES POLARIZATION AND DISEASE PROGRESSION IN GLIOBLASTOMA Open
Glioblastoma, IDH-wildtype (GBM, WHO grade 4) is the most common primary intracranial malignant tumor of adults and is characterized by an immunosuppressive tumor micro-environment (TME) and poor clinical outcomes. CLEC5A is a protein-codi…
View article: TMIC-48. HYPOXIC AND PERI-NECROTIC ZONES IN GLIOBLASTOMA CAUSE HIPPO-OFF SIGNALING, POTENTIALLY SUPPORTING GLIOMA STEM CELLS
TMIC-48. HYPOXIC AND PERI-NECROTIC ZONES IN GLIOBLASTOMA CAUSE HIPPO-OFF SIGNALING, POTENTIALLY SUPPORTING GLIOMA STEM CELLS Open
Glioblastoma (GBM) is the most common and malignant primary brain tumor with pre-necrotic and post-necrotic growth phases. The development of necrosis is associated with extensive tumor micro-environmental (TME) rearrangement and rapid bio…
View article: TMIC-16. INTRATUMORAL THROMBOSIS INITIATES HYPOXIA AND NECROSIS TO DRIVE TUMOR PROGRESSION THROUGH DRAMATIC TUMOR MICROENVIRONMENTAL ALTERATION
TMIC-16. INTRATUMORAL THROMBOSIS INITIATES HYPOXIA AND NECROSIS TO DRIVE TUMOR PROGRESSION THROUGH DRAMATIC TUMOR MICROENVIRONMENTAL ALTERATION Open
All GBM molecular subsets share the common trait of accelerated progression following necrosis which cannot be adequately explained by cellular proliferation arising from accumulated genetic alterations. We suggest that development of necr…
View article: Histones of Neutrophil Extracellular Traps Induce CD11b Expression in Brain Pericytes Via Dectin-1 after Traumatic Brain Injury
Histones of Neutrophil Extracellular Traps Induce CD11b Expression in Brain Pericytes Via Dectin-1 after Traumatic Brain Injury Open
View article: A Novel Prognostic Signature Based on Glioma Essential Ferroptosis-Related Genes Predicts Clinical Outcomes and Indicates Treatment in Glioma
A Novel Prognostic Signature Based on Glioma Essential Ferroptosis-Related Genes Predicts Clinical Outcomes and Indicates Treatment in Glioma Open
Background Ferroptosis is a form of programmed cell death (PCD) that has been implicated in cancer progression, although the specific mechanism is not known. Here, we used the latest DepMap release CRISPR data to identify the essential fer…
View article: Histones of Neutrophil Extracellular Traps (NETs) Activate Brain Pericyte via Dectin-1 in Traumatic Brain Injury
Histones of Neutrophil Extracellular Traps (NETs) Activate Brain Pericyte via Dectin-1 in Traumatic Brain Injury Open
Brain pericyte is unique and indispensable part of blood-brain barrier (BBB), and contributes to several pathological processes in traumatic brain injury (TBI). However, the cellular and molecular mechanisms about how pericyte is regulated…
View article: Overcoming T-cell exhaustion in glioblastoma
Overcoming T-cell exhaustion in glioblastoma Open
Immunotherapy is typically ineffective against glioblastoma (GBM) due to inherent and adaptive resistance. Initial immunotherapy results for GBM have been disappointing. In this regard, T-cell exhaustion is a major barrier to successful tr…
View article: Advanced modalities and surgical theories in glioma resection
Advanced modalities and surgical theories in glioma resection Open
Surgical resection is the core of the comprehensive treatment of glioma. However, with infiltrative growth features, glioma often invades the surrounding area, making surgical resection more difficult. This review introduces relevant topic…