Jia‐Hong Gao
YOU?
Author Swipe
View article: Building hierarchically nested structure by rapid neural sequences
Building hierarchically nested structure by rapid neural sequences Open
Hierarchically nested structures are fundamental to human cognition, enabling complex behaviors across domains including language, planning, and mathematics. However, the neural mechanisms that enable the flexible construction of these hie…
View article: The genetic architecture of brainstem structures
The genetic architecture of brainstem structures Open
The brainstem houses numerous nuclei and tracts that serve vital functions. Genome-wide associations with brainstem substructure volumes have been explored in European individuals, yet other ancestries remain under-represented. Here, we co…
View article: Altered Connectivity of Locus Coeruleus in Insomnia Disorder During Wakefulness and <scp>NREM</scp> Sleep
Altered Connectivity of Locus Coeruleus in Insomnia Disorder During Wakefulness and <span>NREM</span> Sleep Open
Insomnia disorder (ID) frequently coexists with substantial psychiatric comorbidity, particularly anxiety and depression. The neurobiological mechanisms underlying the association between ID and emotional dysregulation remain incompletely …
View article: Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes Open
Brain structure and function show substantial individual differences, finely controlled by genes, environments, and their interactions. Despite the increasing knowledge about genetic and environmental main effects, gene‐environment interac…
View article: Cortical hierarchy underlying homeostatic sleep pressure alleviation
Cortical hierarchy underlying homeostatic sleep pressure alleviation Open
Sleep dissipates accumulated sleep pressure and restores brain function, yet how this recovery unfolds across the cortical hierarchy remains unclear. Here, we record simultaneous electroencephalogram (EEG) and blood oxygen level-dependent …
View article: IEFS-GMB: Gradient Memory Bank-Guided Feature Selection Based on Information Entropy for EEG Classification of Neurological Disorders
IEFS-GMB: Gradient Memory Bank-Guided Feature Selection Based on Information Entropy for EEG Classification of Neurological Disorders Open
Deep learning-based EEG classification is crucial for the automated detection of neurological disorders, improving diagnostic accuracy and enabling early intervention. However, the low signal-to-noise ratio of EEG signals limits model perf…
View article: Reciprocal Predictions Between Reading Achievement and Cognitive Flexibility Development in Children and the Mediating Roles of the Left Middle Frontal Gyrus
Reciprocal Predictions Between Reading Achievement and Cognitive Flexibility Development in Children and the Mediating Roles of the Left Middle Frontal Gyrus Open
The development of reading skills and cognitive flexibility is crucial for success in childhood and adulthood. Although previous studies demonstrate the existing links between the development of cognitive flexibility and the reading acquis…
View article: Positive school climate boosts children’s reading achievement, mental health and cortical thinning
Positive school climate boosts children’s reading achievement, mental health and cortical thinning Open
Growing evidence underscores school climate as an important protective factor for children's academic achievement and mental health. However, whether and how school climate impacts child development from behavioral to brain has remained la…
View article: Progresses and clinical application of super-resolution ultrasound imaging: a narrative review
Progresses and clinical application of super-resolution ultrasound imaging: a narrative review Open
Microcirculation plays a crucial role in maintaining normal physiological functions in the human body by facilitating the exchange of materials between tissues and blood through a network of microvessels with diameters less than 100 μm. It…
View article: AI shares emotion with humans across languages and cultures
AI shares emotion with humans across languages and cultures Open
Effective and safe human-machine collaboration requires the regulated and meaningful exchange of emotions between humans and artificial intelligence (AI). Current AI systems based on large language models (LLMs) can provide feedback that m…
View article: Human Brain-Wide Activation of Sleep Rhythms
Human Brain-Wide Activation of Sleep Rhythms Open
During sleep, our brain undergoes highly synchronized activity, orchestrated by distinct neural rhythms. Little is known about the associated brain activation during these sleep rhythms, and even less about their functional implications. I…
View article: Deep-learning segmentation and multi-ancestry GWAS enhance genetic discovery of the cerebellum
Deep-learning segmentation and multi-ancestry GWAS enhance genetic discovery of the cerebellum Open
The genetic architecture of cerebellar substructure volumes is crucial for understanding their functions in cognition, emotion, and neuropsychiatric disorders. We utilized deep-learning segmentation and multi-ancestry analysis to identify …
View article: Recurrent code for working memory maintenance in the human frontal cortex
Recurrent code for working memory maintenance in the human frontal cortex Open
Despite accumulating evidence for the involvement of frontal cortex in working memory, it remains debated whether frontal cortex stores stimulus-specific mnemonic information or coordinates mnemonic representations in sensory areas. Neurop…
View article: Cross-ancestry and sex-stratified genome-wide association analyses of brain white matter principal components
Cross-ancestry and sex-stratified genome-wide association analyses of brain white matter principal components Open
White matter microstructure determines effective communications across brain regions, which can be better characterized by tract-specific principal components from diffusion tensor imaging data. Although genome-wide associations with tract…
View article: The multiscale brain structural re-organization that occurs from childhood to adolescence correlates with cortical morphology maturation and functional specialization
The multiscale brain structural re-organization that occurs from childhood to adolescence correlates with cortical morphology maturation and functional specialization Open
From childhood to adolescence, the structural organization of the human brain undergoes dynamic and regionally heterogeneous changes across multiple scales, from synapses to macroscale white matter pathways. However, during this period, th…
View article: Simultaneous quantification of PCr, Cr, and <scp>pH</scp> in muscle <scp>CEST</scp> ‐ <scp>MRI</scp>
Simultaneous quantification of PCr, Cr, and <span>pH</span> in muscle <span>CEST</span> ‐ <span>MRI</span> Open
Purpose CEST‐MRI allows sensitive in vivo detection of PCr and Cr in muscle. However, the accurate quantification is difficult due to overlapped “peaks” from multiple solutes and mixed contributions from fractional concentration () and exc…
View article: Human Brain-Wide Activation of Sleep Rhythms
Human Brain-Wide Activation of Sleep Rhythms Open
During sleep, our brain undergoes highly synchronized activity, orchestrated by distinct neural rhythms. Little is known about the associated brain activation during these sleep rhythms, and even less about their functional implications. I…
View article: Human Brain-Wide Activation of Sleep Rhythms
Human Brain-Wide Activation of Sleep Rhythms Open
During sleep, our brain undergoes highly synchronized activity, orchestrated by distinct neural rhythms. Little is known about the associated brain activation during these sleep rhythms, and even less about their functional implications. I…
View article: DeepReducer: A linear transformer-based model for MEG denoising
DeepReducer: A linear transformer-based model for MEG denoising Open
Measuring event-related magnetic fields (ERFs) in magnetoencephalography (MEG) is crucial for investigating perceptual and cognitive information processing in both neuroscience research and clinical practice. However, the magnitude of the …
View article: Current status and perspectives of ultrahigh-field magnetic resonance imaging
Current status and perspectives of ultrahigh-field magnetic resonance imaging Open
Magnetic resonance imaging (MRI) is one of the most important imaging modalities used in contemporary clinical radiology research and diagnostic practice due to its non-invasive nature, absence of ionizing radiation, high soft tissue contr…
View article: Increased spindle-related brain activation in right middle temporal gyrus during N2 than N3 among healthy sleepers: Initial discovery and independent sample replication
Increased spindle-related brain activation in right middle temporal gyrus during N2 than N3 among healthy sleepers: Initial discovery and independent sample replication Open
The association between spindle metrics and sleep architecture differs during N2 vs. N3 sleep, the underlying neural mechanism is not clearly illustrated. Here, we tested the discrepancy in spindle-related brain activation between N2 and N…
View article: Linking Changes in Sulcal Morphology to Cognitive Development from Childhood to Adolescence
Linking Changes in Sulcal Morphology to Cognitive Development from Childhood to Adolescence Open
Throughout childhood and adolescence, the development of motor skills and cognitive functions is accompanied by concurrent changes in the morphology of cortical sulci. In this study, we analyzed structural MRI (sMRI) data from a longitudin…
View article: Segregation of the regional radiomics similarity network exhibited an increase from late childhood to early adolescence: A developmental investigation
Segregation of the regional radiomics similarity network exhibited an increase from late childhood to early adolescence: A developmental investigation Open
Brain development is characterized by an increase in structural and functional segregation, which supports the specialization of cognitive processes within the context of network neuroscience. In this study, we investigated age-related cha…
View article: Human Brain-Wide Activation of Sleep Rhythms
Human Brain-Wide Activation of Sleep Rhythms Open
During sleep, our brain undergoes highly synchronized activity, orchestrated by distinct neural rhythms. Little is known about the associated brain activation during these sleep rhythms, and even less about their functional implications. I…
View article: Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups
Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups Open
Normative modeling of brain morphometric data can inform about the clinical significance of deviations from typical patterns in brain structure. Their usefulness, however, is dependent on their applicability to diverse ethnoracial groups. …
View article: The genetic architecture of brainstem structures
The genetic architecture of brainstem structures Open
The brainstem contains numerous nuclei and tracts with vital functions. Genome-wide associations with brainstem substructure volumes are explored in European individuals, however other ancestries are under-represented. Here, we conducted t…