Jian Cao
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View article: Optic disc morphometrics as a potential ocular biomarker for depression: evidence from two cross-sectional cohort studies
Optic disc morphometrics as a potential ocular biomarker for depression: evidence from two cross-sectional cohort studies Open
Depression, which is increasingly prevalent among older adults, has traditionally been diagnosed through symptom-based questionnaires. However, emerging evidence suggests that retinal changes could serve as objective biomarkers for depress…
View article: Evaluation of liver fibrosis staging in patients with chronic hepatitis via the gadolinium washout rate: a comparative study with magnetic resonance elastography and pathology
Evaluation of liver fibrosis staging in patients with chronic hepatitis via the gadolinium washout rate: a comparative study with magnetic resonance elastography and pathology Open
GWR is superior to MRE in diagnosing advanced fibrosis (≥ F3), offering higher predictive values and clinical net benefit. It provides a cost-effective, noninvasive alternative to MRE.
View article: Mobilization and protection of the ureter during laparoscopic total hysterectomy for cervical fibroids
Mobilization and protection of the ureter during laparoscopic total hysterectomy for cervical fibroids Open
Cervical fibroids (CFs) grow in the narrowest part of the uterus, which is adjacent to the ureter, uterine vessels and their branches. The ureter is at risk of being divided, thermally injured, and/or misligated when handling the vessels d…
View article: Association between the immune-inflammation index and the severity and clinical outcomes of patients with inflammatory bowel disease: a systematic review and meta-analysis
Association between the immune-inflammation index and the severity and clinical outcomes of patients with inflammatory bowel disease: a systematic review and meta-analysis Open
View article: A case of severe retroperitoneal chyle leakage and subsequent chylothorax secondary to partial laparoscopic nephrectomy
A case of severe retroperitoneal chyle leakage and subsequent chylothorax secondary to partial laparoscopic nephrectomy Open
Retroperitoneal chyle leakage combined with chylothorax after nephrectomy is rare in clinical practice. We report a 41-year-old female who developed severe chyloretroperitoneum along with subsequent chylothorax after partial nephrectomy. T…
View article: Study on the Transformation Process of Thyroid Fine‐Needle Aspiration Liquid‐Based Cytology to Whole‐Slide Image
Study on the Transformation Process of Thyroid Fine‐Needle Aspiration Liquid‐Based Cytology to Whole‐Slide Image Open
Objective Analyse and summarise the reasons for failure in the digital acquisition of thyroid liquid‐based cytology (LBC) slides and the technical challenges, and explore methods to obtain reliable and reproducible whole digital slide imag…
View article: Chemical and Field-Effect Passivation of Multifunctional 2d/2d Nanocomposites for High-Efficiency and Durable Perovskite Solar Cells
Chemical and Field-Effect Passivation of Multifunctional 2d/2d Nanocomposites for High-Efficiency and Durable Perovskite Solar Cells Open
View article: Comprehensive prognosis assessment of cardiovascular magnetic resonance parametric mapping in light chain amyloidosis
Comprehensive prognosis assessment of cardiovascular magnetic resonance parametric mapping in light chain amyloidosis Open
View article: Efficacy and safety of immune checkpoint inhibitors rechallenge in advanced solid tumors: a systematic review and meta-analysis
Efficacy and safety of immune checkpoint inhibitors rechallenge in advanced solid tumors: a systematic review and meta-analysis Open
Introduction The efficacy and safety of re-administration of immune checkpoint inhibitors (ICIs) in advanced solid tumors lacks consensus and is of great concern to clinicians. This study aimed to investigate the efficacy and adverse effec…
View article: Prognostic value of left atrial strain in patients with stage II light-chain cardiac amyloidosis receiving cardiac magnetic resonance imaging: a prospective cohort study
Prognostic value of left atrial strain in patients with stage II light-chain cardiac amyloidosis receiving cardiac magnetic resonance imaging: a prospective cohort study Open
LA booster strain is an independent prognostic indicator in stage II AL-CA and is superior to metrics of LV function. LA strain has potential clinical value as an early prognostic marker and may aid in identifying underdiagnosed patients w…
View article: Indocyanine green localization for preoperative <scp>CT</scp>‐guided localization of multiple pulmonary nodules
Indocyanine green localization for preoperative <span>CT</span>‐guided localization of multiple pulmonary nodules Open
Objectives This study assesses the safety and efficacy of using indocyanine green (ICG) for preoperative CT‐guided localization of multiple pulmonary nodules. Methods We included patients who underwent CT‐guided preoperative ICG localizati…
View article: Real-world insights for the evolving intervention strategy for non-mild acute pancreatitis: 35-year experience in a Chinese Tertiary Center
Real-world insights for the evolving intervention strategy for non-mild acute pancreatitis: 35-year experience in a Chinese Tertiary Center Open
Background: With the accumulation of experience and evidence, guidelines for invasive intervention for acute pancreatitis (AP) have continuously evolved, followed in Peking Union Medical College Hospital (PUMCH). We aimed to review AP case…
View article: Single Cell Map of Human Azoospermia Testis Caused by Cyclophosphamide Chemotherapy
Single Cell Map of Human Azoospermia Testis Caused by Cyclophosphamide Chemotherapy Open
Chemotherapeutic drugs will affect the process of spermatogenesis. However, most current studies on the effects of chemotherapeutic drugs on spermatogenesis are based on mouse models, with a shortage of human body evidence. In addition, th…
View article: Deep Learning-Based Evidence Enhancement for Early Diagnosis of Aortic Dissection from Non-Contrast Ct: A Multicentre Study
Deep Learning-Based Evidence Enhancement for Early Diagnosis of Aortic Dissection from Non-Contrast Ct: A Multicentre Study Open
View article: MA18.03 Preliminary Safety and Treatment Data of A Phase 3 Trial: Hypofractionated vs Conventional Fractionated Concurrent Chemoradiation for LS-SCLC
MA18.03 Preliminary Safety and Treatment Data of A Phase 3 Trial: Hypofractionated vs Conventional Fractionated Concurrent Chemoradiation for LS-SCLC Open
View article: 424P Pyrotinib plus capecitabine for trastuzumab-resistant, HER2-positive advanced breast cancer: Updated survival results from the phase II PICTURE trial
424P Pyrotinib plus capecitabine for trastuzumab-resistant, HER2-positive advanced breast cancer: Updated survival results from the phase II PICTURE trial Open
View article: Insights into the Three-Component Coupling Reactions of Aldehydes, Alkynes, and Amines Catalyzed by N-heterocyclic Carbene Silver: A DFT Study
Insights into the Three-Component Coupling Reactions of Aldehydes, Alkynes, and Amines Catalyzed by N-heterocyclic Carbene Silver: A DFT Study Open
Density functional theory (DFT) was used to investigate the three-component coupling reactions of aldehydes, alkynes, and amines (A3 coupling) using N-heterocyclic carbene silver as the catalyst. This study reveals that the addition reacti…
View article: Values of new ultrasonic imaging methods for the diagnosis of apical Takotsubo syndrome
Values of new ultrasonic imaging methods for the diagnosis of apical Takotsubo syndrome Open
RT-3DE and STI played an indispensable role in visually and quantitatively inspecting the abnormalities of patients with TTS, including in diagnosis and follow-up.
View article: Density Functional Theory Analysis of the Copolymerization of Cyclopropenone with Ethylene Using a Palladium Catalyst
Density Functional Theory Analysis of the Copolymerization of Cyclopropenone with Ethylene Using a Palladium Catalyst Open
Density functional theory has been used to elucidate the mechanism of Pd copolymerization of cyclopropenone with ethylene. The results reveal that introducing ethylene and cyclopropenone to Pd catalyst is thermodynamically feasible and gen…
View article: N-Heterocyclic Carbene Silver Complex Modified Polyacrylonitrile Fiber/MIL-101(Cr) Composite as Efficient Chiral Catalyst for Three-Component Coupling Reaction
N-Heterocyclic Carbene Silver Complex Modified Polyacrylonitrile Fiber/MIL-101(Cr) Composite as Efficient Chiral Catalyst for Three-Component Coupling Reaction Open
Complex asymmetric synthesis can be realized by the chiral induction of amino acids in nature. It is of great significance to design a new biomimetic catalytic system for asymmetric synthesis. In this context, we report the preparation and…
View article: Density Functional Theory Study of the Regioselectivity in Copolymerization of bis-Styrenic Molecules with Propylene Using Zirconocene Catalyst
Density Functional Theory Study of the Regioselectivity in Copolymerization of bis-Styrenic Molecules with Propylene Using Zirconocene Catalyst Open
Density functional theory (DFT) was used to study the regioselectivity of the copolymerization of propylene and the bis-styrenic molecules (DVB and BVPE) using a zirconocene catalyst. This study reveals the following: when hydrogen is intr…
View article: Risk stratification of indeterminate thyroid nodules by novel multigene testing: a study of Asians with a high risk of malignancy
Risk stratification of indeterminate thyroid nodules by novel multigene testing: a study of Asians with a high risk of malignancy Open
Molecular testing of indeterminate thyroid nodules informs about the presence of point mutations, insertions/deletions, copy number variants, RNA fusions, transcript alterations and miRNA expression. American Thyroid Association (ATA) guid…
View article: Neurological Manifestations and Neuroimaging Findings of Acute Intermittent Porphyria Patients
Neurological Manifestations and Neuroimaging Findings of Acute Intermittent Porphyria Patients Open
View article: Targeted Near-Infrared Fluorescence Imaging With Iodized Indocyanine Green in Preoperative Pulmonary Localization: Comparative Efficacy, Safety, Patient Perception With Hook-Wire Localization
Targeted Near-Infrared Fluorescence Imaging With Iodized Indocyanine Green in Preoperative Pulmonary Localization: Comparative Efficacy, Safety, Patient Perception With Hook-Wire Localization Open
Background Precise preoperative localization is of great importance to improve the success rate and reduce the operation time of VATS surgery. This study aimed to assess the efficacy, safety, patient perception between CT-guided indocyanin…
View article: Subclassification of the Bethesda Category III (AUS/FLUS): A study of thyroid FNA cytology based on ThinPrep slides from the National Cancer Center in China
Subclassification of the Bethesda Category III (AUS/FLUS): A study of thyroid FNA cytology based on ThinPrep slides from the National Cancer Center in China Open
Background The atypia of an undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) category in the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is a heterogeneous category, which includes variou…
View article: Correlation Between the Evolution of Somatic Alterations During Lymphatic Metastasis and Clinical Outcome in Penile Squamous Cell Carcinoma
Correlation Between the Evolution of Somatic Alterations During Lymphatic Metastasis and Clinical Outcome in Penile Squamous Cell Carcinoma Open
Penile squamous cell carcinoma (PSCC) is a rare malignancy with poor survival after standard treatment. Although genomic alterations of PSCC have been characterized in several latest studies, the association between the formation of somati…
View article: Clinical evaluation of p16<sup>INK4a</sup> immunocytology in cervical cancer screening: A population‐based cross‐sectional study from rural China
Clinical evaluation of p16<sup>INK4a</sup> immunocytology in cervical cancer screening: A population‐based cross‐sectional study from rural China Open
Background Cervical cancer screening with cytology suffers from low sensitivity, whereas the efficiency of human papillomavirus (HPV)‐based screening is limited by low specificity. The authors evaluated a novel p16 INK4a immunocytology app…
View article: P76.63 Dacomitinib Induces a Drastic Response in Metastatic Brain Lesions of Patients with EGFR-mutant Non-small-cell Lung Cancer: A Brief Report
P76.63 Dacomitinib Induces a Drastic Response in Metastatic Brain Lesions of Patients with EGFR-mutant Non-small-cell Lung Cancer: A Brief Report Open
View article: OA02.06 PSM Analysis Results from REFRACT: A Multi-Center Cohort Study Investigating the Treatment Patterns in EGFR-Mutant Unresectable LA- NSCLC
OA02.06 PSM Analysis Results from REFRACT: A Multi-Center Cohort Study Investigating the Treatment Patterns in EGFR-Mutant Unresectable LA- NSCLC Open
View article: Reversibility of Cardiac Involvement in Acromegaly Patients After Surgery: 12-Month Follow-up Using Cardiovascular Magnetic Resonance
Reversibility of Cardiac Involvement in Acromegaly Patients After Surgery: 12-Month Follow-up Using Cardiovascular Magnetic Resonance Open
Our findings demonstrated that some of the cardiac involvement in acromegaly patients is reversible after surgical treatment which lowers hormone levels. Endocrine remission and gender significantly impacted postoperative cardiac reversibi…