Jiahui Ding
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View article: Remnant cholesterol associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction following percutaneous coronary intervention
Remnant cholesterol associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction following percutaneous coronary intervention Open
Remnant cholesterol (RC) serves as an important indicator for assessing atherosclerotic cardiovascular disease, however, correlation with contrast-induced acute kidney injury (CI-AKI) remains unclear. This research investigated the relatio…
View article: Predictive Value of the Atherogenic Index of Plasma and Systemic Inflammation Response Index for Contrast-Induced Acute Kidney Injury in STEMI Patients Undergoing PCI
Predictive Value of the Atherogenic Index of Plasma and Systemic Inflammation Response Index for Contrast-Induced Acute Kidney Injury in STEMI Patients Undergoing PCI Open
Objective This study aimed to investigate the association of the atherogenic index of plasma (AIP) and systemic inflammation response index (SIRI) with contrast-induced acute kidney injury (CI-AKI) in ST-segment elevation myocardial infarc…
View article: Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner
Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner Open
Maternal viral infection during pregnancy can have lasting consequences on offspring immune development. Zika virus (ZIKV) is known to trigger maternal immune activation (MIA), yet its impact on fetal and postnatal innate immunity remains …
View article: Decoding functional and developmental trajectories of tissue-resident uterine dendritic cells through integrative omics
Decoding functional and developmental trajectories of tissue-resident uterine dendritic cells through integrative omics Open
Uterine dendritic cells (uDCs) are critical for endometrial function, yet their origin and functional roles during the pre- and post-implantation periods in the human endometrium remain largely unknown. We hypothesize that distinct uDC sub…
View article: Development and Testing a New Online Dynamic Nomogram for Contrast-Induced Acute Kidney Injury in Elderly Patients with ST-Segment Elevation Myocardial Infarction
Development and Testing a New Online Dynamic Nomogram for Contrast-Induced Acute Kidney Injury in Elderly Patients with ST-Segment Elevation Myocardial Infarction Open
A new online dynamic nomogram was developed to provide a practical tool for CI-AKI risk stratification in elderly STEMI patients, aiding personalized prevention strategies.
View article: Sexual dimorphism in lung transcriptomic adaptations in fetal alcohol spectrum disorders
Sexual dimorphism in lung transcriptomic adaptations in fetal alcohol spectrum disorders Open
Current fetal alcohol spectrum disorders (FASD) studies primarily focus on alcohol’s actions on the fetal brain although respiratory infections are a leading cause of morbidity/mortality in newborns. The limited studies examining the pulmo…
View article: Decoding Functional and Developmental Trajectories of Tissue-Resident Uterine Dendritic Cells Through Integrative Omics
Decoding Functional and Developmental Trajectories of Tissue-Resident Uterine Dendritic Cells Through Integrative Omics Open
View article: The Predictive Value of SII Combined with UHR for Contrast-Induced Acute Kidney Injury in Patients with Acute Myocardial Infarction After Percutaneous Coronary Intervention
The Predictive Value of SII Combined with UHR for Contrast-Induced Acute Kidney Injury in Patients with Acute Myocardial Infarction After Percutaneous Coronary Intervention Open
High SII and high UHR are risk factors for AMI, and their combination can improve the accuracy of predicting CI-AKI in AMI patients after PCI.The prognosis of CI-AKI in AMI patients is worse than in the general population.
View article: Hydroquinone impairs trophoblast migration and invasion via AHR-twist-IFITM1 axis
Hydroquinone impairs trophoblast migration and invasion via AHR-twist-IFITM1 axis Open
View article: Glutathione hybrid poly (beta-amino ester)-plasmid nanoparticles for enhancing gene delivery and biosafety
Glutathione hybrid poly (beta-amino ester)-plasmid nanoparticles for enhancing gene delivery and biosafety Open
View article: TPGS-b-PBAE Copolymer-Based Polyplex Nanoparticles for Gene Delivery and Transfection In Vivo and In Vitro
TPGS-b-PBAE Copolymer-Based Polyplex Nanoparticles for Gene Delivery and Transfection In Vivo and In Vitro Open
Poly (β-amino ester) (PBAE) is an exceptional non-viral vector that is widely used in gene delivery, owing to its exceptional biocompatibility, easy synthesis, and cost-effectiveness. However, it carries a high surface positive charge that…
View article: Chitosan-Functionalized Poly(β-Amino Ester) Hybrid System for Gene Delivery in Vaginal Mucosal Epithelial Cells
Chitosan-Functionalized Poly(β-Amino Ester) Hybrid System for Gene Delivery in Vaginal Mucosal Epithelial Cells Open
Gene therapy displays great promise in the treatment of cervical cancer. The occurrence of cervical cancer is highly related to persistent human papilloma virus (HPV) infection. The HPV oncogene can be cleaved via gene editing technology t…
View article: Editorial: Environmental toxicity in reproduction
Editorial: Environmental toxicity in reproduction Open
EDITORIAL article Front. Physiol., 19 December 2023Sec. Developmental Physiology Volume 14 - 2023 | https://doi.org/10.3389/fphys.2023.1351594
View article: HbBIN2 Functions in Plant Cold Stress Resistance through Modulation of HbICE1 Transcriptional Activity and ROS Homeostasis in Hevea brasiliensis
HbBIN2 Functions in Plant Cold Stress Resistance through Modulation of HbICE1 Transcriptional Activity and ROS Homeostasis in Hevea brasiliensis Open
Cold stress poses significant limitations on the growth, latex yield, and ecological distribution of rubber trees (Hevea brasiliensis). The GSK3-like kinase plays a significant role in helping plants adapt to different biotic and abiotic s…
View article: Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice
Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice Open
We unfurled the remarkable therapeutic ability of BAR in abortion-prone mice, and this was achieved by mobilizing MDSCs, thus favoring immune tolerance and angiogenesis at the maternal-fetal interface.
View article: In view of ovarian steroidogenesis and luteal construction to explore the effects of Bushen Huoxue recipe in mice of ovarian hyperstimulation
In view of ovarian steroidogenesis and luteal construction to explore the effects of Bushen Huoxue recipe in mice of ovarian hyperstimulation Open
BSHXR restored the abnormally high progesterone level by regulating the CYP11A1 and HSD3B1 expression as well as promoted luteal angiogenesis, which was related with LHCGR-MEK1/2-ERK1/2-VEGFA/FGF2 signaling pathway in the ovary. This effec…
View article: Twist1–IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection
Twist1–IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection Open
An efficient immune defense against pathogens requires sufficient basal sensing mechanisms that can deliver prompt responses. Type I IFNs are protective against acute viral infections and respond to viral and bacterial infections, but thei…
View article: Poster Presentations
Poster Presentations Open
Problem: Epidemiological studies in humans implicate maternal expression of different combinations of KIRs, which are a family of cell surface receptors that tune cellular activation status, as being predictive in pregnancy complication on…
View article: Paclitaxel-loaded ROS-responsive nanoparticles for head and neck cancer therapy
Paclitaxel-loaded ROS-responsive nanoparticles for head and neck cancer therapy Open
High intracellular reactive oxygen species (ROS) level is characteristic of cancer cells and could act as a target for the efficient targeted drug delivery for cancer treatment. Consequently, biomaterials that react to excessive levels of …
View article: Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure
Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure Open
View article: Illuminating the Live-Cell Dynamics of Hepatitis B Virus Covalently Closed Circular DNA Using the CRISPR-Tag System
Illuminating the Live-Cell Dynamics of Hepatitis B Virus Covalently Closed Circular DNA Using the CRISPR-Tag System Open
Understanding the formation and maintenance of HBV cccDNA has always been a central issue in the study of HBV pathobiology. However, little progress has been made due to the lack of robust assay systems and its resistance to genetic modifi…
View article: Bushen Antai Recipe Alleviates Embryo Absorption by Enhancing Immune Tolerance and Angiogenesis at Maternal-Fetal Interface Via Mobilizing Mdscs in Abortion-Prone Mice
Bushen Antai Recipe Alleviates Embryo Absorption by Enhancing Immune Tolerance and Angiogenesis at Maternal-Fetal Interface Via Mobilizing Mdscs in Abortion-Prone Mice Open
View article: Improving Manifold Microchannel Heat Sink Cooling Performance and Thermal Uniformity by Changing the Fins Below the Manifold Channel
Improving Manifold Microchannel Heat Sink Cooling Performance and Thermal Uniformity by Changing the Fins Below the Manifold Channel Open
View article: Bushen Antai Recipe Ameliorates Immune Microenvironment and Maternal-Fetal Vascularization in Stat3-Deficient Abortion Mice
Bushen Antai Recipe Ameliorates Immune Microenvironment and Maternal-Fetal Vascularization in Stat3-Deficient Abortion Mice Open
View article: Mechanisms of immune regulation by the placenta: Role of type I interferon and interferon‐stimulated genes signaling during pregnancy*
Mechanisms of immune regulation by the placenta: Role of type I interferon and interferon‐stimulated genes signaling during pregnancy* Open
Pregnancy is a unique condition where the maternal immune system is continuously adapting in response to the stages of fetal development and signals from the environment. The placenta is a key mediator of the fetal/maternal interaction by …
View article: Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system
Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system Open
The hypoxic nature of tumours limits the efficiency of oxygen-dependent photodynamic therapy (PDT). Hence, in this study, indocyanine green (ICG)-loaded lipid-coated zinc peroxide (ZnO2) nanoparticles (ZnO2@Lip-ICG) w…
View article: Long-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes, and Can Be Partially Reversed by Antiviral Therapy
Long-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes, and Can Be Partially Reversed by Antiviral Therapy Open
Global temporal quantitative proteomic and transcriptomic analysis using long-term hepatitis B virus (HBV)-infected primary human hepatocytes uncovered extensive remodeling of the host proteome and transcriptome and revealed cytopathic eff…
View article: Co-Delivery of p53 Restored and E7 Targeted Nucleic Acids by Poly (Beta-Amino Ester) Complex Nanoparticles for the Treatment of HPV Related Cervical Lesions
Co-Delivery of p53 Restored and E7 Targeted Nucleic Acids by Poly (Beta-Amino Ester) Complex Nanoparticles for the Treatment of HPV Related Cervical Lesions Open
The p53 gene has the highest mutation frequency in tumors, and its inactivation can lead to malignant transformation, such as cell cycle arrest and apoptotic inhibition. Persistent high-risk human papillomavirus (HR-HPV) infection is the l…
View article: Intrinsic Sexual Dimorphism in the Placenta Determines the Differential Response to Benzene Exposure
Intrinsic Sexual Dimorphism in the Placenta Determines the Differential Response to Benzene Exposure Open
View article: Placenta‐derived interferon‐stimulated gene 20 controls ZIKA virus infection
Placenta‐derived interferon‐stimulated gene 20 controls ZIKA virus infection Open