Jiahui Du
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View article: Computer Vision for Rare Diseases: A Scoping Review
Computer Vision for Rare Diseases: A Scoping Review Open
Rare diseases, though individually infrequent, collectively affect over 300 million people worldwide. The clinical heterogeneity, delayed diagnosis, and limited expertise associated with rare diseases present substantial challenges for ear…
View article: Holographic Turbulence and the Fractal Dimension of the Turbulent Horizon
Holographic Turbulence and the Fractal Dimension of the Turbulent Horizon Open
We study two-dimensional turbulence driven by a scalar operator within the framework of the AdS/CFT correspondence, where the external driving source is used to sustain a quasi-steady turbulent state. We numerically construct dynamical and…
View article: PLAGL1-IGF2 axis regulates osteogenesis of postnatal condyle development
PLAGL1-IGF2 axis regulates osteogenesis of postnatal condyle development Open
View article: Early Warning of Anthracnose on Illicium verum Through the Synergistic Integration of Environmental and Remote Sensing Time Series Data
Early Warning of Anthracnose on Illicium verum Through the Synergistic Integration of Environmental and Remote Sensing Time Series Data Open
Anthracnose on Illicium verum Hook.f (I. verum) significantly affects the yield and quality of I. verum, and timely detection methods are urgently needed for early control. However, early warning is difficult due to two major challenges, i…
View article: Well-Defined Cu Precatalysts Indicate Design Rules for Reactivity in Nitrate Electroreduction
Well-Defined Cu Precatalysts Indicate Design Rules for Reactivity in Nitrate Electroreduction Open
The electrochemical nitrate reduction reaction (NO3RR) to ammonia (NH3) is a promising route for sustainable NH3 synthesis. Cu-based materials are the most used and promising catalysts for this reaction. Ho…
View article: Advanced biomaterial-based strategies for craniofacial bone regeneration
Advanced biomaterial-based strategies for craniofacial bone regeneration Open
Craniofacial bone reconstruction presents unique anatomical and functional challenges that differ from those associated with systemic skeletal repair, necessitating specialized regenerative strategies. Despite considerable advancements in …
View article: Spotlight on USP30: structure, function, disease and target inhibition
Spotlight on USP30: structure, function, disease and target inhibition Open
This review comprehensively summarizes the current understanding of ubiquitin-specific protease 30 (USP30), covering its structural characteristics, functions in cellular processes, associations with diseases, diagnostic and therapeutic st…
View article: LncRNA SLC7A11AR promotes lung adenocarcinoma progression by inhibiting ferroptosis via promoting SLC7A11 expression
LncRNA SLC7A11AR promotes lung adenocarcinoma progression by inhibiting ferroptosis via promoting SLC7A11 expression Open
Non-small cell lung cancer (NSCLC) is a prevalent classification of human lung cancer with a variety of clinical pathological features. Several key factors and associated signaling pathways have played pivotal roles in the progression of N…
View article: Face-based machine learning diagnostics: applications, challenges and opportunities
Face-based machine learning diagnostics: applications, challenges and opportunities Open
View article: Cerebral infarction and hemorrhage caused by Streptococcus gordonii infective endocarditis: A case report
Cerebral infarction and hemorrhage caused by Streptococcus gordonii infective endocarditis: A case report Open
View article: “Confined Eutectic” Strategy for Visual Refrigeration Responsive Fluorescent Materials with Easy Preparation and Multi‐Color Tunability
“Confined Eutectic” Strategy for Visual Refrigeration Responsive Fluorescent Materials with Easy Preparation and Multi‐Color Tunability Open
The temperature response window is a very critical parameter for evaluating temperature sensing performance of thermofluorochromic materials, and its regulation has long been a key focus in this field. Especially, the indication of refrige…
View article: Unbiased Max-Min Embedding Classification for Transductive Few-Shot Learning: Clustering and Classification Are All You Need
Unbiased Max-Min Embedding Classification for Transductive Few-Shot Learning: Clustering and Classification Are All You Need Open
Convolutional neural networks and supervised learning have achieved remarkable success in various fields but are limited by the need for large annotated datasets. Few-shot learning (FSL) addresses this limitation by enabling models to gene…
View article: ERCC3 serves as a prognostic biomarker for hepatocellular carcinoma and positively regulates cell proliferation and migration
ERCC3 serves as a prognostic biomarker for hepatocellular carcinoma and positively regulates cell proliferation and migration Open
This study is the first to reveal the association between high ERCC3 expression and poor prognosis in HCC and to elucidate its immunomodulatory role in HCC. Unlike previous studies, we found that ERCC3 promotes HCC progression by regulatin…
View article: Machine learning-based bulk RNA analysis reveals a prognostic signature of 13 cell death patterns and potential therapeutic target of SMAD3 in acute myeloid leukemia
Machine learning-based bulk RNA analysis reveals a prognostic signature of 13 cell death patterns and potential therapeutic target of SMAD3 in acute myeloid leukemia Open
View article: Retraction Note: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6
Retraction Note: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6 Open
View article: Multiomics-Based Deep Learning Prediction of Prognosis and Therapeutic Response in Patients With Extensive-Stage Small Cell Lung Cancer Receiving Chemoimmunotherapy: A Retrospective Cohort Study
Multiomics-Based Deep Learning Prediction of Prognosis and Therapeutic Response in Patients With Extensive-Stage Small Cell Lung Cancer Receiving Chemoimmunotherapy: A Retrospective Cohort Study Open
We developed prediction model based on multi-omics demonstrated satisfactory performance in predicting chemoimmunotherapy response in patients with ES-SCLC. The random forest prediction model, in particular, provides accurate response and …
View article: Semi-Analytical Method For Sliding Adhesion Contact of One-Dimensional Hexagonal Piezoelectric Quasicrystals Coating
Semi-Analytical Method For Sliding Adhesion Contact of One-Dimensional Hexagonal Piezoelectric Quasicrystals Coating Open
View article: Constructing An S-Scheme Fe 2 O 3 /Mns Heterojunction For Efficient Photocatalytic H 2 Evolution In Visible Light
Constructing An S-Scheme Fe 2 O 3 /Mns Heterojunction For Efficient Photocatalytic H 2 Evolution In Visible Light Open
View article: Resistance mechanisms and prospects of trastuzumab
Resistance mechanisms and prospects of trastuzumab Open
Breast cancer that overexpresses Human Epidermal Growth Factor Receptor 2 (HER2+) due to gene amplification or overexpression constitutes 15-20% of all breast cancer cases. Trastuzumab, the first FDA-approved monoclonal antibody targeting …
View article: RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6
RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6 Open
Our findings have identified compelling molecular targets and distinctive diagnostic markers for the clinical management of breast cancer. This data will serve as crucial guidance for further research in the field.
View article: Programmed BRD9 Degradation and Hedgehog Signaling Activation via Silk‐Based Core‐Shell Microneedles Promote Diabetic Wound Healing
Programmed BRD9 Degradation and Hedgehog Signaling Activation via Silk‐Based Core‐Shell Microneedles Promote Diabetic Wound Healing Open
Wound healing impairment in diabetes mellitus is associated with an excessive inflammatory response and defective regeneration capability with suppressed Hedgehog (Hh) signaling. The bromodomain protein BRD9, a subunit of the non‐canonical…
View article: Constructing and identifying an eighteen-gene Tumor Microenvironment Prognostic Model for Non-Small Cell Lung Cancer
Constructing and identifying an eighteen-gene Tumor Microenvironment Prognostic Model for Non-Small Cell Lung Cancer Open
Background The tumor microenvironment (TME) plays a crucial role in tumorigenesis and tumor progression. This study aimed to identify novel TME-related biomarkers and develop a prognostic model for patients with non-small-cell lung cancer …
View article: ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis
ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis Open
View article: ERCC3 serves as a prognostic biomarker for hepatocellular carcinoma and positively regulates cell proliferation and migration
ERCC3 serves as a prognostic biomarker for hepatocellular carcinoma and positively regulates cell proliferation and migration Open
Background ERCC3 is an important member of the nucleotide excision repair (NER) pathway, and its overexpression is involved in the development of a variety of cancers and is a potential factor for poor tumor prognosis. Currently, the expre…
View article: Retraction Note: A novel positive feedback loop of linc02042 and c-Myc mediated by YBX1 promotes tumorigenesis and metastasis in esophageal squamous cell carcinoma
Retraction Note: A novel positive feedback loop of linc02042 and c-Myc mediated by YBX1 promotes tumorigenesis and metastasis in esophageal squamous cell carcinoma Open
View article: Retraction Note: The novel circular RNA circ-CAMK2A enhances lung adenocarcinoma metastasis by regulating the miR-615-5p/fibronectin 1 pathway
Retraction Note: The novel circular RNA circ-CAMK2A enhances lung adenocarcinoma metastasis by regulating the miR-615-5p/fibronectin 1 pathway Open
View article: ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling
ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling Open
ARID1B haploinsufficiency in humans causes Coffin-Siris syndrome, associated with developmental delay, facial dysmorphism, and intellectual disability. The role of ARID1B has been widely studied in neuronal development, but whether it also…
View article: Dilation and energy evolution mechanisms of sandstone under true-triaxial mining unloading conditions
Dilation and energy evolution mechanisms of sandstone under true-triaxial mining unloading conditions Open
The study of sandstone dilation characteristics under actual mining and excavation conditions promotes the safe and efficient development of underground engineering. Accordingly, this study employs true-triaxial testing to reveal the influ…
View article: Stereuins A–F: Isopentenyl Benzene Congeners with Antibacterial and Neurotrophic Activities from Stereum Hirsutum Hfg27
Stereuins A–F: Isopentenyl Benzene Congeners with Antibacterial and Neurotrophic Activities from Stereum Hirsutum Hfg27 Open
View article: Brittleness index evaluation of gas-bearing sandstone under triaxial compression conditions
Brittleness index evaluation of gas-bearing sandstone under triaxial compression conditions Open
Brittleness is a critical property in gas-bearing rock excavation and reservoir fracturing. This paper analyzes the three types of brittleness indices in detail, proposes new indices, and conducts relevant conventional triaxial tests for a…