Jialin Cui
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View article: Solvent‐Directed in Situ Stacking Modulation of 2D Covalent Organic Frameworks for Selective Separation of Xylene Isomers
Solvent‐Directed in Situ Stacking Modulation of 2D Covalent Organic Frameworks for Selective Separation of Xylene Isomers Open
The precise regularity of stacking modes in two‐dimensional covalent organic frameworks (2D COFs) remains insufficiently understood, and achieving precise control during synthesis is highly challenging. Here, we show that the interlayer st…
View article: Integrated Analysis of Phenotypic and Hepatic Transcriptomic Profiles Reveals Enhanced Cold Tolerance in Triploid Crucian Carp
Integrated Analysis of Phenotypic and Hepatic Transcriptomic Profiles Reveals Enhanced Cold Tolerance in Triploid Crucian Carp Open
Cold stress poses a critical threat to fish survival by triggering metabolic dysfunction, oxidative damage, immune suppression, and apoptosis. However, hybrid polyploid fish triploid crucian carp (3nRCR, 3n = 150) demonstrate superior stre…
View article: Water body size shapes body size evolution via subgenomic selection in allopolyploid fish
Water body size shapes body size evolution via subgenomic selection in allopolyploid fish Open
Allopolyploidization is a major force in species evolution, and studying allopolyploids in diverse environments provides insights into their genetic mechanisms. Here, we investigated how water body size variation influences body size in al…
View article: Blockade of TIGAR prevents CD8+ T cell dysfunction and elicits anti-AML immunity
Blockade of TIGAR prevents CD8+ T cell dysfunction and elicits anti-AML immunity Open
Acute myeloid leukemia (AML) cells and activated T cells rely on aerobic glycolysis for energy metabolism. The TP53-induced glycolysis and apoptosis regulator (TIGAR) inhibits glycolysis and protects AML cells from apoptosis. Preliminary s…
View article: Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the <scp>NLRP3</scp>/<scp>NF</scp>‐<scp>κB</scp> Signaling Pathway
Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the <span>NLRP3</span>/<span>NF</span>‐<span>κB</span> Signaling Pathway Open
Quercetin (QCT) shows great therapeutic potential for hyperuricemia (HUA) associated with gouty arthritis (GA). However, the underlying mechanism of QCT in inhibiting the progression of HUA and GA remains unclear. HUA mouse model was estab…
View article: Prediction of survival in acute myeloid leukemia patients by extracellular to intracellular water ratio and sarcopenia: development and validation of a novel nomogram
Prediction of survival in acute myeloid leukemia patients by extracellular to intracellular water ratio and sarcopenia: development and validation of a novel nomogram Open
Acute myeloid leukemia (AML) commonly affects the elderly with a poor prognosis. Body water composition analysis provides a new perspective for biomedical research. This study aims to develop and validate a simple nomogram for predicting o…
View article: The research progress of biologics in elderly-onset rheumatoid arthritis (EORA)
The research progress of biologics in elderly-onset rheumatoid arthritis (EORA) Open
Elderly-onset rheumatoid arthritis (EORA) is a distinct subtype of rheumatoid arthritis characterized by heightened treatment challenges due to immune aging and the complexity of comorbidities. This review systematically summarizes the def…
View article: <i>Buyang Huanwu</i> Decoction reduces mitochondrial autophagy in rheumatoid arthritis synovial fibroblasts in hypoxic culture by inhibiting the BNIP3-PI3K/Akt pathway.
<i>Buyang Huanwu</i> Decoction reduces mitochondrial autophagy in rheumatoid arthritis synovial fibroblasts in hypoxic culture by inhibiting the BNIP3-PI3K/Akt pathway. Open
BYHWT inhibits mitochondrial autophagy in IL-1β-induced FLS-RA with hypoxic exposure possibly by inhibiting BNIP3-mediated PI3K/AKT signaling pathway.
View article: Single-crystal chiral two-dimensional supramolecular organic frameworks for tunable circularly polarized luminescence
Single-crystal chiral two-dimensional supramolecular organic frameworks for tunable circularly polarized luminescence Open
Chiral two-dimensional supramolecular organic frameworks (SOFs) with tunable circularly polarized luminescence (CPL) are constructed through the host–guest interactions between a chiral host and luminescent guests.
View article: mtDNA copy number contributes to growth diversity in allopolyploid fish
mtDNA copy number contributes to growth diversity in allopolyploid fish Open
Phenotypic differences between diploid parents and their allotriploid offspring are common in aquaculture breeding. Some allotriploid populations exhibit rapid growth rates and increased body weight, which are significant for supporting fi…
View article: Stabilizing Cu<sup>+</sup> Species in Cu<sub>2</sub>O/CuO Catalyst via Carbon Intermediate Confinement for Selective CO<sub>2</sub>RR
Stabilizing Cu<sup>+</sup> Species in Cu<sub>2</sub>O/CuO Catalyst via Carbon Intermediate Confinement for Selective CO<sub>2</sub>RR Open
Copper oxide nanomaterials have been suggested to be efficient for highly selective multi‐carbon (C 2+ ) production in CO 2 reduction reaction (CO 2 RR), due to the introduction of surface Cu + species from oxide catalysts. However, the Cu…
View article: Tailoring Treatment for Elderly Lung Cancer Patients: Evaluating the Clinical Benefit of Surgery and Adjuvant Therapy
Tailoring Treatment for Elderly Lung Cancer Patients: Evaluating the Clinical Benefit of Surgery and Adjuvant Therapy Open
Background Surgery and adjuvant therapy are still the primary treatments for lung cancer,however, there is a lack of clear treatment guidelines specifically tailored for elderly patients with lung cancer. The objective of our study is to e…
View article: Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis
Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis Open
Objective. Deficiencies in klotho are implicated in various kidney dysfunctions including diabetic nephropathy (DN) related to inflammatory responses. Klotho is closely related to inflammatory responses and is a potential target for amelio…
View article: Peptides for diagnosis and treatment of ovarian cancer
Peptides for diagnosis and treatment of ovarian cancer Open
Ovarian cancer is the most deadly gynecologic malignancy, and its incidence is gradually increasing. Despite improvements after treatment, the results are unsatisfactory and survival rates are relatively low. Therefore, early diagnosis and…
View article: In Vitro Binding Effects of the Ecdysone Receptor−Binding Domain and PonA in Plutella xylostella
In Vitro Binding Effects of the Ecdysone Receptor−Binding Domain and PonA in Plutella xylostella Open
Both insect ecdysone receptors and ultraspiracle belong to the nuclear receptor family. They form a nanoscale self-assembling complex with ecdysteroids in cells, transit into the nucleus, bind with genes to initiate transcription, and perf…
View article: Dynamic Response Analysis of Floating Nuclear Power Plant Containment Under Marine Environment
Dynamic Response Analysis of Floating Nuclear Power Plant Containment Under Marine Environment Open
Floating nuclear containment is in a harsher environment than conventional onshore nuclear containment. In view of the Marine environment under the condition of floating nuclear power plant containment structure safety, combined water dyna…
View article: Network pharmacology study of the mechanism underlying the therapeutic effect of Zhujing pill and its main component oleanolic acid against diabetic retinopathy
Network pharmacology study of the mechanism underlying the therapeutic effect of Zhujing pill and its main component oleanolic acid against diabetic retinopathy Open
Diabetic retinopathy (DR) is the leading cause of blindness in the working population worldwide, with few effective drugs available for its treatment in the early stages. The Zhujing pill (ZJP) is well-established to enhance the early symp…
View article: Correlations of expression of nuclear and mitochondrial genes in triploid fish
Correlations of expression of nuclear and mitochondrial genes in triploid fish Open
The expression of nuclear and mitochondrial genes, as well as their coordinated control, regulates cell proliferation, individual development, and disease in animals. However, the potential coregulation between nuclear and mitochondrial ge…
View article: Improving problem detection in peer assessment through pseudo-labeling using semi-supervised learning
Improving problem detection in peer assessment through pseudo-labeling using semi-supervised learning Open
An online peer-assessment system typically allows students to give textual feedback to their peers, with the goal of helping the peers improve their work. The amount of help that students receive is highly dependent on the quality of the r…
View article: Insta-Reviewer: A Data-Driven Approach for Generating Instant Feedback on Students' Project Reports
Insta-Reviewer: A Data-Driven Approach for Generating Instant Feedback on Students' Project Reports Open
Providing timely feedback is crucial in promoting academic achievement and student success. However, for multifarious reasons (e.g., limited teaching resources), feedback often arrives too late for learners to act on the feedback and impro…
View article: The formation and biological characterization of two allotriploid fish derived from interploid crosses
The formation and biological characterization of two allotriploid fish derived from interploid crosses Open
Interploid cross is regularly observed in plants and often results in phenotypic changes, including reduced fertility and heterosis. Yet few triploids have been observed in animals due to the rare coexistence of diploid and allotetraploid …
View article: The Prognostic Value of Sarcopenia in Acute Myeloid Leukemia Patients and the Development and Validation of a Novel Nomogram for Predicting Survival
The Prognostic Value of Sarcopenia in Acute Myeloid Leukemia Patients and the Development and Validation of a Novel Nomogram for Predicting Survival Open
Background Acute myeloid leukemia (AML) occurs frequently in the elderly, of whom the prognosis is dismal. Sarcopenia is a progressive and generalized skeletal muscle disorder associated with an increased possibility of adverse outcomes. T…
View article: Interactions between mitochondrial and nuclear genomes and co-regulation of mitochondrial and nuclear gene expression in reciprocal intergeneric hybrids between Carassius auratus red var. × Cyprinus carpio L.
Interactions between mitochondrial and nuclear genomes and co-regulation of mitochondrial and nuclear gene expression in reciprocal intergeneric hybrids between Carassius auratus red var. × Cyprinus carpio L. Open
Genetic interactions between nuclear and mitochondrial genomes always play an important role in growth and development. However, it is not feasible to directly perform these studies in some animals. The reciprocal hybrid fishes obtained fr…
View article: Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway
Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway Open
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the a…